drugset / Trial / NCT00234871
Tarka® vs. Lotrel® in Hypertensive, Diabetic Subjects With Renal Disease (TANDEM)
RandomizedParallel-groupOpen-labelTreatment
Summary
The primary objective of this study is to determine if trandolapril/verapamil (Tarka®) is superior to amlodipine/benazepril (Lotrel®) in reduction of albuminuria in hypertensive subjects with Type 2 diabetes mellitus (DM) and diabetic nephropathy
Timeline
- Start
- 2004-01
- Primary completion
- 2005-03
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amlodipine | Other / unclassified | 10 mg | — |
| Comparator | Benazepril | Unknown | 20 mg | — |
| Comparator | Verapamil | Other / unclassified | 240 mg | — |
| Comparator | trandolapril | Small molecule | 4 mg | — |