Efficacy of Simplified Two Drug Kaletra Regimen vs. Kaletra Triple Drug Standard of Care Regimen in Treatment naïve HIV Infected Patients

Phase 3 Completed 152 enrolled Abbott

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to obtain a preliminary assessment of the antiviral activity and tolerability of simplified Kaletra dual agent therapy as initial treatment for HIV infection, relative to a Kaletra three drug standard of care reference arm.

Timeline

Start: 2005-01
Primary completion: 2007-06
Completion: 2008-06

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Tenofovir	Small molecule	300 mg	—
Background	Lopinavir	Other / unclassified	400 mg	—
Background	Ritonavir	Other / unclassified	100 mg	—

Efficacy of Simplified Two Drug Kaletra Regimen vs. Kaletra Triple Drug Standard of Care Regimen in Treatment naïve HIV Infected Patients

Summary

Timeline

Drugs

Indications