drugset / Trial / NCT00237718
Provision of Antioxidant Therapy in Hemodialysis (PATH) Study
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Studies have shown that end stage renal disease (ESRD) patients have higher levels of blood markers which their body makes in response to increased stress and injury. An increase in these markers have been shown to be related to cardiovascular disease and death in ESRD patients. This study will examine whether antioxidant therapy (Vitamin E and alpha lipoic acid) may decrease these markers.
Timeline
- Start
- 2006-04
- Primary completion
- 2010-09
- Completion
- 2010-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Alpha, gamma, beta, and delta (mixed) tocopherols | Unknown | 666 iu | Oral |
| Comparator | alpha-lipoic acid | Small molecule | 600 mg | — |