drugset / Trial / NCT00237718

Provision of Antioxidant Therapy in Hemodialysis (PATH) Study

NCT00237718

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Studies have shown that end stage renal disease (ESRD) patients have higher levels of blood markers which their body makes in response to increased stress and injury. An increase in these markers have been shown to be related to cardiovascular disease and death in ESRD patients. This study will examine whether antioxidant therapy (Vitamin E and alpha lipoic acid) may decrease these markers.

Timeline

Start
2006-04
Primary completion
2010-09
Completion
2010-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Alpha, gamma, beta, and delta (mixed) tocopherols Unknown 666 iu Oral
Comparator alpha-lipoic acid Small molecule 600 mg