drugset / Trial / NCT00239278
Budesonide / Formoterol in Treatment of Exacerbations of COPD
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine whether the budesonide+formoterol combination is effective in the treatment of exacerbations of COPD with a main emphasis on investigating the effects on inflammation and a secondary emphasis on clinical efficacy
Timeline
- Start
- 2001-01
- Primary completion
- —
- Completion
- 2005-01
Publications
- Bathoorn E, Liesker JJ, Postma DS, Boorsma M, Bondesson E, Koeter GH, Kauffman HF, van Oosterhout AJ, Kerstjens HA. Anti-inflammatory effects of combined budesonide/formoterol in COPD exacerbations. COPD. 2008 Oct;5(5):282-90. doi: 10.1080/15412550802363360.
- Bathoorn E, Liesker J, Postma D, Koeter G, van Oosterhout AJ, Kerstjens HA. Safety of sputum induction during exacerbations of COPD. Chest. 2007 Feb;131(2):432-8. doi: 10.1378/chest.06-2216.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Budesonide | Small molecule | 400 ug | Inhaled |
| Subject | Formoterol | Other / unclassified | 12 ug | Inhaled |
| Subject | Prednisolone | Other / unclassified | 30 mg | Oral |