drugset / Trial / NCT00252798

ZD1839 (Iressa™) and Concurrent Chemo-Radiation in Patients With Locally Advanced Non Small Cell Lung Cancer

NCT00252798

Phase 1 Completed 44 enrolled AstraZeneca
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The primary objective of the trial is to determine the Maximum tolerated dose, if any, of the combination of daily ZD1839 250 mg with carboplatin AUC 2 and 60 Gray (Gy) irradiation and up to 45 mg/m2 paclitaxel.

Timeline

Start
2002-07
Primary completion
Completion
2005-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule
Subject Gefitinib Small molecule 250 mg
Subject Paclitaxel Small molecule 45 mg/m2