A Study of the Effectiveness and Safety of Topiramate for the Prevention of Migraine

Phase 3 Completed 211 enrolled Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Ortho-McNeil Neurologics, Inc. · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

The primary purpose of this study is to evaluate the effectiveness and safety of topiramate (an epilepsy medication) compared with placebo in the prevention of migraine.

Timeline

Start: 2000-10
Primary completion: —
Completion: 2001-12

Publications

Results Silberstein SD, Hulihan J, Karim MR, Wu SC, Jordan D, Karvois D, Kamin M. Efficacy and tolerability of topiramate 200 mg/d in the prevention of migraine with/without aura in adults: a randomized, placebo-controlled, double-blind, 12-week pilot study. Clin Ther. 2006 Jul;28(7):1002-11. doi: 10.1016/j.clinthera.2006.07.003.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Topiramate	Small molecule	200 mg	Oral

A Study of the Effectiveness and Safety of Topiramate for the Prevention of Migraine

Summary

Timeline

Publications

Drugs

Indications