drugset / Trial / NCT00254618

A Study of Asacol Absorption, Metabolism and Excretion in Children and Adolescents With Ulcerative Colitis.

NCT00254618

Phase 1 Terminated 34 enrolled Warner Chilcott
RandomizedParallel-groupOpen-label

Summary

The purpose of this randomized, open-label, parallel-group study is to determine how the body absorbs and eliminates mesalamine following administration of either 30 mg/kg/day, 60 mg/kg/day or 90 mg/kg/day as 400 mg delayed-release tablets given every 12 hours of 28 days to children and adolescents with active ulcerative colitis.

Timeline

Start
2005-10
Primary completion
2008-06
Completion
2008-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Mesalamine Small molecule 30 mg/kg Oral
Subject Mesalamine Small molecule 60 mg/kg Oral
Subject Mesalamine Small molecule 90 mg/kg Oral

Indications