drugset / Trial / NCT00271206
Effect of Progesterone on Smoking Behavior in Male and Female Smokers
RandomizedParallel-groupDouble-blindTreatment
Summary
Past research on nicotine addiction has shown that changes in estradiol and progesterone hormone levels during menstruation may cause women to respond differently than men to nicotine. The purpose of this study is to examine the effects of progesterone on smoking behavior, nicotine withdrawal symptoms, and the reinforcing effects of smoking in men and women addicted to nicotine.
Timeline
- Start
- 2004-09
- Primary completion
- 2008-09
- Completion
- 2008-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Progesterone | Other / unclassified | 200 mg | Oral |
| Comparator | Progesterone | Other / unclassified | 400 mg | Oral |