drugset / Trial / NCT00271206

Effect of Progesterone on Smoking Behavior in Male and Female Smokers

NCT00271206

RandomizedParallel-groupDouble-blindTreatment

Summary

Past research on nicotine addiction has shown that changes in estradiol and progesterone hormone levels during menstruation may cause women to respond differently than men to nicotine. The purpose of this study is to examine the effects of progesterone on smoking behavior, nicotine withdrawal symptoms, and the reinforcing effects of smoking in men and women addicted to nicotine.

Timeline

Start
2004-09
Primary completion
2008-09
Completion
2008-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Progesterone Other / unclassified 200 mg Oral
Comparator Progesterone Other / unclassified 400 mg Oral

Indications