Drugs / Progesterone
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Progesterone

Other / unclassified

Developed for
infertility disorder · female infertility · polycystic ovary syndrome · pregnancy disorder · menstrual disorder · long QT syndrome · nicotine dependence · osteoporosis
+72 more · premature menopause · primary ovarian failure · progesterone resistance · cocaine dependence · coronary artery disorder · COVID-19 · endometrial cancer · endometrial disorder · endometrial endometrioid adenocarcinoma · insomnia · male infertility · postmenopausal atrophic vaginitis · preeclampsia · pregnancy disorder with abortive outcome · premenstrual tension · traumatic brain injury · alcohol dependence · Alzheimer disease · arthropathy · atherosclerosis · bulimia nervosa · cerebrovascular disorder · cervical intraepithelial neoplasia · chronic graft versus host disease · cocaine abuse · cognitive impairment with or without cerebellar ataxia · congenital heart disease · coronary atherosclerosis · depressive disorder · developmental disability · dry eye syndrome · dysmenorrhea · endometrial hyperplasia without atypia · endometrial polyp · endometriosis · epilepsy · female breast carcinoma · fetal growth restriction · functional hypothalamic amenorrhea · HIV infectious disease · hormone receptor-positive breast cancer · major depressive disorder · obstetric disorder · periventricular leukomalacia · post-traumatic stress disorder · pregnancy loss, recurrent, 4 · preterm premature rupture of the membranes · secondary amenorrhea · stroke disorder · substance-related disorder · traumatic encephalopathy · type 2 diabetes mellitus · urolithiasis · vulvar lichen sclerosus · amenorrhea · arteriosclerosis disorder · brain edema · brain injury · breast disorder · cannabis dependence · cervix disorder · glioblastoma · habitual spontaneous abortion · low implantation of placenta · manic bipolar affective disorder · methamphetamine dependence · placenta praevia · schizoaffective disorder · substance withdrawal syndrome · Turner syndrome · twin to twin transfusion syndrome · uterine carcinoma
Investigated by
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · National Institute of Mental Health (NIMH) · IBSA Institut Biochimique SA · University of Virginia · Ferring Pharmaceuticals · National Heart, Lung, and Blood Institute (NHLBI)
+255 more · National Institute on Drug Abuse (NIDA) · Peking Union Medical College Hospital · University of North Carolina, Chapel Hill · Yale University · Indiana University · Insel Gruppe AG, University Hospital Bern · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · University Hospital Brussels · Abbott · American Heart Association · Assiut University · Emory University · Fundacion Dexeus · Medical University of South Carolina · Mount Sinai Hospital, Canada · National Cancer Institute (NCI) · National Institutes of Health (NIH) · Purdue University · Thomas Jefferson University · University of British Columbia · University of Minnesota · ART Fertility Clinics LLC · CRG UZ Brussel · Daré Bioscience, Inc. · David Wright · Fundacion Dexeus · Grünenthal GmbH · HaEmek Medical Center, Israel · Instituto Bernabeu · Instituto Valenciano de Infertilidad, IVI VALENCIA · Massachusetts General Hospital · Mayo Clinic · Medical University of Vienna · Nanjing University · National Institute on Aging (NIA) · Ohio State University · Productos Científicos S. A. de C. V. · Rabin Medical Center · TherapeuticsMD · University Hospital, Montpellier · University Magna Graecia · University of Illinois at Chicago · University of Pennsylvania · Wake Forest University Health Sciences · Washington University School of Medicine · Alexandria University · American Medical Society for Sports Medicine · American University of Beirut Medical Center · BHR Pharma, LLC · Bac Ninh 1 Obstetrics and Pediatrics Hospital, Bac Ninh, Vietnam · Bac Ninh 2 Obstetrics and Pediatrics Hospital, Bac Ninh, Vietnam · Basel Women's University Hospital · Baystate Medical Center · Beijing Chao Yang Hospital · Beijing Tiantan Hospital · Ben-Gurion University of the Negev · Besins Laboratory, Belgium · Beth Israel Deaconess Medical Center · Bezmialem Vakif University · Brain & Behavior Research Foundation · Brigham and Women's Hospital · CEMIC Buenos Aires · CIHR Canadian HIV Trials Network · Caixia Liu · Canadian Institutes of Health Research (CIHR) · Cantonal Hospital of St. Gallen · Carolinas Medical Center · Cedars-Sinai Medical Center · Centre Hospitalier Universitaire Vaudois · Centro A.F. de Estudios Tecnologicos, S.A. · Chiang Mai University · Children's Hospital of Philadelphia · Chiu Yee Liona Poon · Chongqing Medical University · all 261 on the full record

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansion US (FDA) PROGESTERONE 2001-09-17 fda.gov
Approved US (FDA) PROGESTERONE 1974-11-01 fda.gov

Trials 210 · started per year

today
US approved 1974
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 07 trials
Phase 0 NCT06616077 Jun 2022 → Apr 2023 endometrial disorder, progesterone resistance Reproductive Health Research Insritute, Chile Completed No outcome recorded
Phase 0 NCT05091866 Apr 2022 → Dec 2024 gliosarcoma Emory University Terminated No outcome recorded
Phase 0 NCT04104984 Feb 2020 → Sep 2021 Assiut University Unknown No outcome recorded
Phase 0 NCT03687021 Oct 2018 Peking Union Medical College Hospital Unknown No outcome recorded
Phase 0 NCT02486757 Apr 2015 → Mar 2016 menstrual disorder Massachusetts General Hospital Completed No outcome recorded
Phase 0 NCT01483365 Dec 2011 → Dec 2014 menstrual disorder Wolfson Medical Center Unknown No outcome recorded
Phase 0 NCT00929006 Jun 2008 → Oct 2025 overdue University of Virginia Recruiting No outcome recorded
Phase 119 trials
Phase 1 NCT06668896 Sep 2026 → Nov 2027 expected Daré Bioscience, Inc. Not yet recruiting No outcome recorded
Phase 1 NCT07173361 Jan → May 2026 McMaster University Completed No outcome recorded
Phase 1 NCT05980091 Sep 2023 → Dec 2026 female infertility ART Fertility Clinics LLC Suspended No outcome recorded
Phase 1 NCT05969795 Sep 2023 → Apr 2026 overdue female infertility, pregnancy disorder ART Fertility Clinics LLC Recruiting No outcome recorded
Phase 1 NCT05678192 Dec 2021 → Mar 2023 Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare Completed No outcome recorded
Phase 1 NCT05418426 Aug 2020 → Apr 2021 postmenopausal atrophic vaginitis Daré Bioscience, Inc. Completed No outcome recorded
Phase 1 NCT04365127 Apr → Aug 2020 COVID-19 Sara Ghandehari Completed No outcome recorded
Phase 1 NCT03737656 Nov 2018 → May 2019 Grünenthal GmbH Completed No outcome recorded
Phase 1 NCT03340701 Nov 2017 → Jun 2018 Thomas Jefferson University Completed No outcome recorded
Phase 1 NCT02272647 Dec 2014 → Dec 2016 Mayo Clinic Completed No outcome recorded
Phase 1/25 trials
Phase 1/2 NCT03774745 Feb → Jul 2019 University of California, Davis Terminated No outcome recorded
Phase 1/2 NCT01057511 Dec 2009 → Aug 2011 Peking Union Medical College Hospital Completed No outcome recorded
Phase 1/2 NCT01147770 Sep 2008 → Jan 2010 infertility disorder University Hospital Brussels Completed No outcome recorded
Phase 1/2 NCT00048646 May 2002 → Sep 2005 traumatic brain injury David Wright Completed No outcome recorded
Phase 1/2 NCT00001322 Jun 1994 → Mar 2020 National Institute of Mental Health (NIMH) Completed No outcome recorded
Phase 232 trials
Phase 2 NCT07436793 Jun 2026 → Jun 2030 expected endometrial disorder, endometrial endometrioid adenocarcinoma New Mexico Cancer Research Alliance Recruiting No outcome recorded
Phase 2 NCT06807580 May 2025 → Feb 2027 expected Emory University Recruiting No outcome recorded
Phase 2 NCT05982470 Aug 2023 → Jun 2025 cerebrovascular disorder, cognitive impairment with or without cerebellar ataxia Beijing Tiantan Hospital Unknown No outcome recorded
Phase 2 NCT04865029 Jul 2021 → Jan 2022 COVID-19 Tulane University Terminated No outcome recorded
Phase 2 NCT04938011 Jul 2021 → Jun 2023 infertility disorder Nanjing University Unknown No outcome recorded
Phase 2 NCT04645446 Feb 2021 → Oct 2022 dry eye syndrome SIFI SpA Completed No outcome recorded
Phase 2 NCT04225221 Feb 2020 → Apr 2022 bulimia nervosa University of North Carolina, Chapel Hill Completed No outcome recorded
Phase 2 NCT04051320 Jan 2020 → Jul 2022 postpartum depression University of North Carolina, Chapel Hill Completed No outcome recorded
Phase 2 NCT03990051 Oct 2019 → Oct 2021 chronic graft versus host disease Glia, LLC Completed No outcome recorded
Phase 2 NCT03701490 Mar 2019 → Sep 2022 infertility disorder IBSA Institut Biochimique SA Completed No outcome recorded
Phase 2/36 trials
Phase 2/3 NCT06530459 Aug 2024 → Apr 2027 expected arthropathy, menstrual disorder National University Hospital, Singapore Recruiting No outcome recorded
Phase 2/3 NCT02187224 Sep 2016 → Sep 2021 alcohol dependence, post-traumatic stress disorder Yale University Completed No outcome recorded
Phase 2/3 NCT01308814 Oct 2010 → Mar 2016 depressive disorder University of North Carolina, Chapel Hill Completed No outcome recorded
Phase 2/3 NCT00928213 Aug 2009 → Dec 2010 preeclampsia Ben-Gurion University of the Negev Unknown No outcome recorded
Phase 2/3 NCT00632099 Feb 2008 → Sep 2012 cocaine dependence New York State Psychiatric Institute Completed No outcome recorded
Phase 2/3 NCT00775242 Apr 2007 → Nov 2008 Centro A.F. de Estudios Tecnologicos, S.A. Completed No outcome recorded
Phase 335 trials
Phase 3 NCT07613528 Mar 2027 → Sep 2029 expected pregnancy disorder University Hospital, Montpellier Not yet recruiting No outcome recorded
Phase 3 NCT06851754 Jul 2025 → Dec 2031 expected primary ovarian failure Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Recruiting No outcome recorded
Phase 3 NCT06644794 Mar 2025 → Sep 2027 expected female infertility Shandong University of Traditional Chinese Medicine Recruiting No outcome recorded
Phase 3 NCT05899010 Jul 2023 → Jun 2027 expected infertility disorder Fundacion Dexeus Recruiting No outcome recorded
Phase 3 NCT04549116 Oct 2022 → Jan 2026 overdue infertility disorder IBSA Institut Biochimique SA Active not recruiting No outcome recorded
Phase 3 NCT04806919 Apr 2021 → Feb 2025 pregnancy loss, recurrent, 4 University Hospital, Ghent Completed No outcome recorded
Phase 3 NCT03540225 Apr 2020 → Apr 2022 pregnancy disorder Chiu Yee Liona Poon Withdrawn No outcome recorded
Phase 3 NCT03565211 Jul 2018 → Jul 2019 Ferring Pharmaceuticals Completed No outcome recorded
Phase 3 NCT02633878 Oct 2017 → Oct 2025 Heilongjiang University of Chinese Medicine Completed No outcome recorded
Phase 3 NCT03309709 Oct 2017 → Oct 2019 endometrial polyp University Magna Graecia Unknown No outcome recorded
Phase 461 trials
Phase 4 NCT07448597 Aug 2026 → May 2028 expected preeclampsia Medical University of South Carolina Not yet recruiting No outcome recorded
Phase 4 NCT07466199 Jul → Aug 2026 overdue ovarian dysfunction Instituto Valenciano de Infertilidade de Lisboa Not yet recruiting No outcome recorded
Phase 4 NCT07508657 Apr 2026 → Jun 2029 expected infertility disorder Kirstine Kirkegaard Not yet recruiting No outcome recorded
Phase 4 NCT06497894 Jan → Jul 2026 overdue insomnia Insel Gruppe AG, University Hospital Bern Recruiting No outcome recorded
Phase 4 NCT07350317 Jan → Dec 2026 expected Trust Fertility Clinic Not yet recruiting No outcome recorded
Phase 4 NCT07649668 Nov 2025 → May 2026 Dr Mudassar Saeed Pansota Completed No outcome recorded
Phase 4 NCT06306404 Oct 2025 → Oct 2029 expected insomnia VU University of Amsterdam Not yet recruiting No outcome recorded
Phase 4 NCT07523295 May → Nov 2025 Medicare Hospital (Pvt) Limited Completed No outcome recorded
Phase 4 NCT06610305 Sep 2024 → Jun 2028 expected major depressive disorder University of North Carolina, Chapel Hill Recruiting No outcome recorded
Phase 4 NCT05954962 Dec 2023 → Apr 2025 Instituto Bernabeu Completed No outcome recorded
Phase not applicable45 trials
NCT07620587 Jun 2026 → Aug 2028 expected Wilfrid Laurier University Recruiting No outcome recorded
NCT07372495 Apr 2026 → Dec 2028 expected preterm premature rupture of the membranes National Hospital of Obstetrics and Gynecology Recruiting No outcome recorded
NCT07496294 Apr 2026 → Oct 2027 expected Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital Not yet recruiting No outcome recorded
NCT07568574 Mar 2026 → May 2028 expected Enhanced Emirates Limited Enrolling by invitation No outcome recorded
NCT07003373 Jul 2025 → Jul 2026 overdue Malihe Mahmoudinia Not yet recruiting No outcome recorded
NCT06928844 Apr → Aug 2025 overdue The General Authority for Teaching Hospitals and Institutes Recruiting No outcome recorded
NCT06715514 Feb 2025 → Dec 2026 expected type 2 diabetes mellitus Lia Bally Recruiting No outcome recorded
NCT06005207 Aug 2023 → Dec 2024 female infertility Nanjing University Unknown No outcome recorded
NCT05232344 Apr 2022 → Feb 2024 infertility disorder University Hospital, Montpellier Completed No outcome recorded
NCT05276531 Apr → Jun 2022 Bezmialem Vakif University Completed No outcome recorded
Also used as a comparator or background therapy in 203 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 07 trials
Phase 0 NCT06870266 Comparator Mar 2025 → Mar 2027 expected Shaare Zedek Medical Center Not yet recruiting No outcome recorded
Phase 0 NCT04597099 Background Oct 2022 → Oct 2025 polycystic ovary syndrome University of Virginia Unknown No outcome recorded
Phase 0 NCT05128071 Comparator Feb 2022 → May 2024 methamphetamine dependence University of Utah Completed No outcome recorded
Phase 0 NCT04426487 Comparator Jun → Sep 2020 traumatic brain injury Minia University Unknown No outcome recorded
Phase 0 NCT04046185 Comparator Oct 2019 → Oct 2021 uterine carcinoma Shanghai First Maternity and Infant Hospital Unknown No outcome recorded
Phase 19 trials
Phase 1 NCT07136922 Comparator Apr → Aug 2026 overdue Calla Lily Clinical Care Ltd Recruiting No outcome recorded
Phase 1 NCT06631547 Comparator Dec 2025 → Jan 2027 expected brain injury Assiut University Not yet recruiting No outcome recorded
Phase 1 NCT06045351 Background Jan 2024 → Jun 2026 overdue anovulation Aga Khan University Recruiting No outcome recorded
Phase 1 NCT04753957 Comparator Jan → Feb 2022 pregnancy disorder Thomas Jefferson University Terminated No outcome recorded
Phase 1 NCT04414020 Comparator Jun → Aug 2020 brain edema Minia University Unknown No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT05737329 Background Mar 2019 → Apr 2023 primary ovarian failure Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare Unknown No outcome recorded
Phase 1/2 NCT00455962 Comparator Jan 2005 → Dec 2011 Massachusetts General Hospital Completed No outcome recorded
Phase 1/2 NCT00455741 Comparator Nov 2000 → Feb 2007 Massachusetts General Hospital Completed No outcome recorded
Phase 223 trials
Phase 2 NCT07010146 Background Oct 2025 → Dec 2029 expected bone remodeling disease, functional hypothalamic amenorrhea University of Virginia Recruiting No outcome recorded
Phase 2 NCT07319715 Comparator Jan 2023 → Aug 2024 pregnancy disorder Benha University Completed No outcome recorded
Phase 2 NCT05555121 Comparator Dec 2022 → Apr 2028 infertility disorder, low implantation of placenta Clinique Ovo Suspended No outcome recorded
Phase 2 NCT05365464 Comparator May 2022 → Dec 2025 pregnancy loss, recurrent, 4 Wake Forest University Health Sciences Withdrawn No outcome recorded
Phase 2 NCT04534881 Comparator Oct 2020 → Jan 2023 St. Louis University Terminated No outcome recorded
Phase 2/310 trials
Phase 2/3 NCT05758064 Comparator Jan → Dec 2023 El Shatby University Hospital for Obstetrics and Gynecology Unknown No outcome recorded
Phase 2/3 NCT04558268 Background Dec 2020 → Jul 2021 pregnancy loss, recurrent, 4 Soroka University Medical Center Unknown No outcome recorded
Phase 2/3 NCT03077633 Comparator Oct 2017 → Jan 2018 cervical incompetence Pediatrix Withdrawn No outcome recorded
Phase 2/3 NCT03058536 Comparator Feb 2017 → Mar 2019 pregnancy disorder Mario Henrique Burlacchini de Carvalho Unknown No outcome recorded
Phase 2/3 NCT02470676 Comparator Jul 2015 → Jul 2018 cervix disorder Hillel Yaffe Medical Center Unknown No outcome recorded
Phase 335 trials
Phase 3 NCT06572761 Background Sep 2026 → May 2030 expected cervical incompetence Assistance Publique - Hôpitaux de Paris Not yet recruiting No outcome recorded
Phase 3 NCT07340827 Background Feb 2026 → Jul 2028 expected infertility disorder Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany Recruiting No outcome recorded
Phase 3 NCT07162961 Background Sep 2025 → Jun 2026 overdue adenomyosis Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 3 NCT06150703 Comparator Jun 2024 → Sep 2027 expected Assistance Publique - Hôpitaux de Paris Recruiting No outcome recorded
Phase 3 NCT05894954 Background Jul 2023 → Oct 2025 cognitive impairment with or without cerebellar ataxia, dementia Alzheimer's Prevention and Reversal Project, Inc. Completed No outcome recorded
Phase 460 trials
Phase 4 NCT06856174 Comparator Apr 2026 → Sep 2027 expected HIV infectious disease Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections Recruiting No outcome recorded
Phase 4 NCT06834594 Comparator Jul 2025 → Jul 2026 overdue Turner syndrome Children's Mercy Hospital Kansas City Recruiting No outcome recorded
Phase 4 NCT06875752 Comparator Apr 2025 → Apr 2026 overdue Dunamenti REK Istenhegyi IVF Center Recruiting No outcome recorded
Phase 4 NCT06896617 Comparator Feb 2025 → Nov 2026 expected infertility disorder Fundacion Clinic per a la Recerca Biomédica Recruiting No outcome recorded
Phase 4 NCT05997563 Comparator Aug 2023 → Aug 2025 Chulalongkorn University Unknown No outcome recorded
Phase not applicable56 trials
NCT07305519 Background Apr 2026 → Apr 2027 expected University of Roma La Sapienza Recruiting No outcome recorded
NCT07415070 Background Mar 2026 → Dec 2027 expected Ningbo University Not yet recruiting No outcome recorded
NCT07409792 Background Feb 2026 → Jan 2027 expected anxiety, depressive disorder, female infertility, sleep disorder Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University Enrolling by invitation No outcome recorded
NCT07425990 Background Feb 2026 → Feb 2027 expected female infertility University of Novi Sad Not yet recruiting No outcome recorded
NCT03637062 Comparator Dec 2024 → Dec 2026 expected QH Medical Technology Ltd. Not yet recruiting No outcome recorded

Press releases naming this drug 5 releases

DateIssuerRelease
2017-09-25 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Reintroduction of Generic Depo-Provera® in the United States tevapharm.com
2017-05-08 Pfizer Collaboration Helps Broaden Access to Pfizer’s Contraceptive, Sayana® Press (medroxyprogesterone acetate), for Women in Some of the World’s Poorest Countries pfizer.com
2012-03-02 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Launch of Generic Prometrium® Capsules in the United States tevapharm.com
2004-10-27 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Approval Of Medroxyprogesterone Acetate Pre-Filled Syringe tevapharm.com
2004-07-29 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Approval Of Medroxyprogesterone Acetate Injectable Suspension tevapharm.com

Evidence & citations 47 cited values

Every value below carries the sentence it was read from. 423 sources stand behind the page.

FieldValueCited text
Known as progesterone “The aim of the study protocol will be to compare the efficacy of subcutaneous progesterone (25 mg / day; Pleyris, IBSA Institut Biochimique SA) with vaginal progesterone (90 mg...” NCT02793908
361

“PURPOSE: To verify sufficient progesterone supplementation during the luteal phase and to determine the efficacy and safety of a natural micronized progesterone vaginal tablet...” PMID 26457065 Jun 2015

“Patients with low serum progesterone will be randomized to receive extra progesterone supplementation in the form of either: * Group A: oral 10 mg dydrogesterone (Duphaston®,...” NCT05758064

“In the present analysis, the subjects received daily in the right and left forearm a transdermal nanostructured formulation of Estriol (0.1%) + Estradiol (0.25%) and...” NCT02033512

“Randomized Controlled Trial Comparing Micronized Progesterone (Amelgen ®) 400 mg BID Versus 400 mg TID for Luteal Support in Artificial Vitrified/Warmed Single Blastocyst...” NCT04806919

Progesterone-50 mg intramuscularly once a day beginning the day after oocyte retrieval continuing until the pregnancy test is negative or if positive, switching to Crinone 8%...” NCT00656201

“Patients in the control group will receive artificial cycle therapy post-IVF-ET: progesterone injection 40 mg/day, or oral dydrogesterone tablets (Duphaston) 20 mg/day, or...” NCT07409792

“Standard-dose continuously-combined bio-identical HRT containing transdermal estradiol 1.5 mg/d (= 2 strokes of Oestrogel® Dispenser) and oral micronized progesterone (= 1...” NCT06497894

“This is combined with 200 mg progesterone (Utrogestan tablets for 2 weeks) adjusted to the menstrual cycle to prevent endometrium carcinoma according to the international MHT...” NCT06306404

“for luteal phase support 600 mg progesterone tablets (Utrogestan; Laboratoires Besins- Iscovesco, Paris, France) or gel 8% intravaginally (Vasclor; Verisfield Ltd, UK) will be applied” NCT01590173

“100 mg progesterone vaginal insert 2 or 3 times daily (BID or TID) (start on the day after oocyte retrieval) until 10 weeks gestation or confirmation of negative pregnancy test.” NCT00802360

“Luteal support was provided as Crinone 8%(®) vaginal progesterone gel (90mg) administered daily, or oral dydrogesterone Duphaston(®) (2× 10mg) administered two times daily.” PMID 25622239 Nov 2014

“The prophylactic use of progesterone during the early phase of pregnancy in women with a history of preterm birth and those with a short cervix can prevent preterm birth.” NCT02511574

progesterone supplementation is started (400 mg vaginal suppositories twice daily and 50 mg intramuscular injections daily) for 5 days before blastocyst transfer.” NCT07003373

“Forehead application of 1% progesterone gel provides corneal antinociception in preclinical models, suggesting it may be useful in alleviating ocular irritations.” PMID 33942724 Feb 2021

Progesterone is a natural neurosteroid that we are trying to use to impede both direct neuronal injury cauesd by and indirectly by surgical trauma.” NCT04414020

“Atrophic subtype support may include: estradiol, progesterone, testosterone, DHEA, pregnenolone, levothyroxine, liothyronine, hydrocortisone.” NCT05894954

“including progesterone alone, human chorionic gonadotropin (hCG) alone, and the combination of progesterone with hCG, in these patients.” PMID 39827385 Jan 2025

“Luteal support will be provided with vaginal progesterone, either Endometrin 100 mg twice daily or Utrogestan 200 mg twice daily.” NCT06870266

Progesterone vaginal ring versus vaginal gel for luteal support with in vitro fertilization: a randomized comparative study.” PMID 23465817 Mar 2013

“one of three doses of a compounded estrogen cream (Bi-est (80:20); 2.0, 2.5, or 3.0 mg)+compounded oral progesterone 100 mg” PMID 23384975 Feb 2013

“Estrogen 100 mcg patch twice weekly with 10 days of oral progesterone monthly for 12 months versus no medication” NCT00827151

“Multidose formulation despensing unit doses of 0.07 g of topical gel containing 0.7 mg of progesteroneNCT04645446

“natural progesterone in a novel subcutaneous formulation (Prolutex) may offer a viable alternative.” NCT07350317

“maintenance treatment ("Mirena", "Progesterone", "Dydrogesterone", or combined oral contraceptive)” NCT05945407

“Also, every 2 months, oral micronized progesterone (200 mg/day x 12 days) will be administered.” NCT01308814

“oral micronized progesterone suspension, 100 mg oral dose at 0800 during each study admission” NCT04597099

“Substituted FET GnRH-a 2 bolus two days before Estradiol 6 mg Progesterone (Crinone) 180 mg” NCT01943812

“inject able progesterone is prescribed and the patient is a candidate for FET transfer.” NCT05189873

progesterone (Prometrium) 200 mg per day for first 12 calendar days of each month” NCT02922348

“All cases received luteal support in the form of progesterone 400 mg twice daily.” NCT03784404

“micronized Progesterone 200mg tablets to be taken orally for 12 days each month” NCT06530459

“Estradiol 1,5 mg + Progesterone 200 mg/Estradiol 1,5 mg + Progesterone 100 mg” NCT05678192

Progesterone 1mmol/L; Estradiol 1mmol/L; Estrone 3mmol/L; Estriol 3mmol/L” NCT00873262

“oral micronized progesterone (Utrogestan) as acute tocolysis agent” NCT01985594

“Estradiol gel 0.1% 1.5mg/ daily + Micronized Progesterone 200mg” NCT05737329

“micronized progesterone (Endometrin, Ferring Pharmaceuticals)” NCT01465373

“29 days (estradiol 1mg/progesterone 100 mg oral capsule)” NCT05418426

“Luteal support with daily progesterone gel = Crinone 8%” NCT02048891

“Vaginal Micronized Progesterone Tablet (Endometrin®)” NCT00296478

“routine luteal phase support with progesterone gel” NCT00750451

“standard vaginal progesterone (200 mg once daily)” NCT07305519

“micronized progesterone 200 mg 3id (Utrogestan®)” NCT04983173

Progesterone 20mg/ i.m./ Qd, 7 days totally.” NCT01057511

“using once daily natural progesterone agent” NCT00329316

Progesterone: Hormone replacement therapy.” NCT02618148

progesterone supplementation (Prometrium)” NCT03504345

“Vaginal Micronized ProgesteroneNCT03832699

“1. Progesterone 1mmol/L” NCT00866437

Progesterone Group” NCT02690129

NCT01428089

NCT00455741

NCT03948022

NCT01810601

NCT06463652

NCT04499131

NCT02913495

NCT00828191

NCT04209543

NCT04549116

NCT00536003

NCT04534881

NCT04190927

NCT05365464

NCT01500863

NCT00632099

NCT00708539

NCT02970552

NCT03457233

NCT00000466

NCT03267771

NCT07136922

NCT02470676

NCT05189145

NCT02601898

NCT01602679

NCT04997525

NCT02350231

NCT05969795

NCT01225835

NCT01942668

NCT01812239

NCT00271206

NCT01269450

NCT06928844

NCT02430233

NCT05276531

NCT01356524

NCT07508657

NCT01798394

NCT04938011

NCT00805207

NCT03540225

NCT01286246

NCT01796522

NCT01147770

NCT05555121

NCT04846218

NCT01046643

NCT00530582

NCT01546454

NCT01010048

NCT00455962

NCT06091436

NCT04837768

NCT04300322

NCT01599494

NCT00206544

NCT02633878

NCT04753957

NCT02460302

NCT04248309

NCT00827983

NCT01428193

NCT03729869

NCT02133573

NCT02316626

NCT01980680

NCT07340827

NCT00946192

NCT07649668

NCT05704036

NCT00732693

NCT02187224

NCT01940653

NCT02467673

NCT00480402

NCT06644794

NCT01954966

NCT03633175

NCT04161989

NCT01237535

NCT01081652

NCT03023514

NCT00001322

NCT01972464

NCT01643980

NCT01589068

NCT01123538

NCT04087408

NCT00775242

NCT00946088

NCT03340701

NCT03701490

NCT02019589

NCT03565211

NCT04507022

NCT07319715

NCT03619707

NCT01959464

NCT01744574

NCT01589081

NCT06036446

NCT01178788

NCT04426487

NCT02673359

NCT02491437

NCT00809939

NCT00579553

NCT02846909

NCT02032797

NCT02697331

NCT01888744

NCT07415070

NCT00361075

NCT05080569

NCT02623881

NCT00954811

NCT02225353

NCT04558268

NCT02145767

NCT03687021

NCT01428245

NCT00000555

NCT02114645

NCT00928213

NCT01927029

NCT07448597

NCT01206998

NCT01464697

NCT00117468

NCT05899010

NCT01432028

NCT06631547

NCT02492451

NCT01762943

NCT03181685

NCT00929006

NCT07613528

NCT04124913

NCT01826747

NCT04675788

NCT00000295

NCT05838105

NCT03120715

NCT05282277

NCT00006399

NCT00001481

NCT03058536

NCT06975943

NCT01031017

NCT00086177

NCT00152438

NCT01941875

NCT07162961

NCT01293747

NCT00646802

NCT04008966

NCT01741376

NCT01840228

NCT02224313

NCT03018366

NCT03498313

NCT00719537

NCT05112692

NCT01790282

NCT03088046

NCT06610305

NCT03343795

NCT04537078

NCT00001259

NCT00696878

NCT00843570

NCT03003949

NCT07436793

NCT02513940

NCT02841137

NCT00919919

NCT00343265

NCT01143064

NCT00702845

NCT00218257

NCT00700492

NCT01126255

NCT03930212

NCT03863613

NCT02304237

NCT02486757

NCT06851754

NCT02338830

NCT03484611

NCT00830765

NCT07523295

NCT01381016

NCT03152942

NCT02969590

NCT03202186

NCT05232344

NCT03202836

NCT04865029

NCT04112368

NCT06572761

NCT03834883

NCT02254577

NCT00565916

NCT05484193

NCT01153581

NCT01112358

NCT03740568

NCT04046185

NCT01023178

NCT01353846

NCT04104984

NCT07568574

NCT06005207

NCT04143880

NCT05980091

NCT00585520

NCT06616077

NCT05312190

NCT04748562

NCT01425541

NCT01773772

NCT03251729

NCT06807580

NCT01176175

NCT05903820

NCT03537287

NCT00247169

NCT01406197

NCT06668896

NCT02363127

NCT00696800

NCT03637062

NCT01809639

NCT00079248

NCT00108238

NCT01504139

NCT05128071

NCT07466199

NCT03720847

NCT01180296

NCT07425990

NCT03440359

NCT00594217

NCT00377923

NCT02779582

NCT03992937

NCT02255175

NCT03211338

NCT05061641

NCT04783857

NCT02685072

NCT02736032

NCT06896617

NCT00302731

NCT03040830

NCT02950935

NCT01698164

NCT01249274

NCT02078869

NCT07620587

NCT02772120

NCT03781466

NCT06856174

NCT05388656

NCT02567552

NCT03737656

NCT02518594

NCT01523483

NCT03781674

NCT00822900

NCT02655146

NCT06875752

NCT00029536

NCT05091866

NCT03740204

NCT03774745

NCT00048646

NCT01441635

NCT00000176

NCT05982470

NCT02579421

NCT04365127

NCT03309709

NCT01670929

NCT04453332

NCT01427595

NCT01811225

NCT00563472

NCT06150703

NCT03734770

NCT00676026

NCT05954962

NCT07372495

NCT04342585

NCT05286554

NCT04278508

NCT04725864

NCT03430050

NCT00005108

NCT01608451

NCT00615550

NCT01780610

NCT01929083

NCT00329914

NCT05062135

NCT02272647

NCT01780558

NCT02950948

NCT02372942

NCT05787509

Known as 17P ClinicalTrials.gov intervention name — accepted as the source's own label NCT03297216
Known as Amelgen “Randomized Controlled Trial Comparing Micronized Progesterone (Amelgen ®) 400 mg BID Versus 400 mg TID for Luteal Support in Artificial Vitrified/Warmed Single Blastocyst...” NCT04806919
Known as BHR401 “The primary objective of the clinical trial is to demonstrate superiority of BHR401 (oral micronized progesterone) versus placebo as a monotherapy for moderate to severe VMS in...” NCT03202186
Known as Callavid “400mg progesterone Callavid, 2 hour wear, twice daily for 7 days” NCT07136922
Known as Crinone “The aim of the study protocol will be to compare the efficacy of subcutaneous progesterone (25 mg / day; Pleyris, IBSA Institut Biochimique SA) with vaginal progesterone (90 mg...” NCT02793908
10

“To compare the safety, efficacy, and tolerability of subcutaneous progesterone (Prolutex, 25 mg; IBSA Institut Biochimique SA) with vaginal progesterone gel (Crinone, 8%; Merck...” PMID 24140033 Oct 2013

“vaginal progesterone(Crinone; Merck-Serono, Hellerup, Denmark) and estradiol(Estrofem; Novo Nordisk, Copenhagen, Denmark) in the luteal phase” NCT01504139

“Luteal support with progesterone only (they will received vaginal P gel (Crinone 8% vaginal gel; Serono, Israel)” NCT01237535

“Substituted FET GnRH-a 2 bolus two days before Estradiol 6 mg Progesterone (Crinone) 180 mg” NCT01943812

“luteal phase support with progesterone (Crinone® %8 vaginal progesterone gel) in IUI cycle” NCT02492451

“Luteal support with daily progesterone gel = Crinone 8%” NCT02048891

crinone (progesterone 8%, vaginal application)” NCT01826747

“Progesterone Vaginal Gel [Crinone]” NCT04124913

NCT03858049

NCT00296478

Known as Crinone 8% “micronized progesterone 90 mg (Crinone 8% ® - Merck)” NCT04719000
Known as Cyclogest “Vaginal progesterone (Cyclogest) 400 mg administered twice daily starting the day after insemination.” NCT07508657
1

Cyclogest 400 mg pessary, twice daily for 7 days” NCT07136922

Known as Cyclogest 400mg “400 mg vaginal progesterone, purchased from the manufacturer (Cyclogest® 400mg, Actavis, United Kingdom), will be applied once daily at bedtime, within two days after cerclage...” NCT03863613
Known as Endometrin Endometrin® (vaginal micronized progesterone tablets) supplemented by intramuscular injection of progesterone in oil (PIO) work as well as PIO alone for women undergoing...” NCT02254577
9

“Artificial Endometrial Preparation for Frozen Thawed Embryo Transfer Applying Either Endometrin or Utrogestan” NCT00345306

“Participants receive 100 mg vaginal progesterone inserts (e.g., Endometrin) administered twice daily.” NCT07319715

“vaginal progesterone - 100 mg Endometrin twice daily until week 8 of pregnancy.” NCT05838105

“micronized progesterone (Endometrin, Ferring Pharmaceuticals)” NCT01465373

“Luteal support: Endometrin 100mg vaginally three times daily” NCT01204840

“Vaginal Micronized Progesterone Tablet (Endometrin®)” NCT00296478

NCT01483365

NCT02510534

NCT03540979

Known as FE 999913 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01710514
Known as m-P “0.45 mg/d oral conjugated equine estrogens (o-CEE) plus 200 mg/d micronized progesterone (m-P) for the first 12 d of each month” PMID 26035291 Jun 2015
Known as medroxyprogesterone acetate “Possible side effects of progesterone (medroxyprogesterone acetate) include; nausea, breast tenderness, changes to liver enzymes, blood clotting profile changes, acne and...” NCT00206544
Known as Medroxyprogesterone Acetate (MPA) ClinicalTrials.gov intervention name — accepted as the source's own label NCT00997893
Known as micronised progesterone “Data suggest that micronised progesterone (mP) in menopausal hormone therapy is safer for the breast than synthetic progestins” PMID 39448218 Oct 2024
1

“Oestradiol cypionate intramuscular (IM) and micronised progesterone oral (PO), in addition to SOC” PMID 34848523 Nov 2021

Known as Micronized natural progesterone ClinicalTrials.gov intervention name — accepted as the source's own label NCT02118051
Known as micronized progesterone “Participants are randomized into three groups, the CEE 0.3 mg/micronized progesterone (MP) 100 mg group; CEE 0.625 mg/MP 100 mg group; CEE 0.625 mg/dydrogesterone 10 mg...” NCT03436303
39

Micronized progesterone 400 mg suppository administered rectally once daily from 16 to 36 weeks of gestation following cervical cerclage. Intended to provide sustained...” NCT07307092

“In the initial comparison of this rotating umbrella trial, megestrol acetate, a progestin, will be compared to micronized progesterone, a form of natural progesterone that is a...” NCT07436793

“We will evaluate the efficacy and safety of Chinese herbal medicine (New "Shoutai Wan", NSTW) and/or oral micronized progesterone (OP) for treating threatened miscarriage in this trial.” NCT02633878

“Oral micronized progesterone will be added (100 mg/day for 12 days/month) in the event of spontaneous vaginal bleeding and/or at 12 months over the 2-year protocol.” NCT06851754

“Prometrium (micronized progesterone USP encapsulated with peanut oil) 200 mg daily for the first 12 days of each month at bedtime” NCT02524561

“Administration of 200 mg of vaginal Micronized Progesterone (100 mg every 12 hours) for a 7-day course” NCT03088046

“Also, every 2 months, oral micronized progesterone (200 mg/day x 12 days) will be administered.” NCT01308814

micronized progesterone 200 mg (Utrogestan, company) as an intra-vaginal tablet once daily” NCT01269450

“estradiol plus micronized progesterone 200 mg daily for women with an intact uterus” NCT00005108

“cyclic micronized progesterone (MP), 200 milligrams per day for 12 days a month” NCT00000466

“with 200 mg micronized progesterone given for 12 days of every month” NCT07010146

“Utrogestan®*: once daily 200mg of micronized progesteroneNCT06715514

micronized progesterone 90 mg (Crinone 8% ® - Merck)” NCT04719000

Micronized progesterone 200mg (Utrogestan®)” NCT04992468

“Drug: Micronized ProgesteroneNCT06856174

NCT06834594

NCT07173361

NCT03642665

NCT05586724

NCT01046708

NCT03068910

NCT02329535

NCT02677259

NCT00755963

NCT04758871

NCT04051320

NCT02086032

NCT03677336

NCT04597099

NCT02989519

NCT01850030

NCT03976544

NCT04225221

NCT03998761

NCT07496294

NCT00154180

NCT02571296

NCT04108039

NCT05997563

Known as MVP “micronized vaginal progesterone (MVP) 600 mg daily” PMID 28333318 May 2017
Known as Natural micronized progesterone Natural micronized progesterone, 400 mg/12 hours vaginal administration” NCT01353846
Known as natural progesterone “Twenty-five women will be randomized to self-administer natural progesterone (Prometrium, 200 mg) vaginally every night starting between gestational week 16 and 24 until week 36” PMID 27965866 Aug 2016
1

NCT02511574

Known as OHP17 “Progesterone (OHP17)” NCT00830765
Known as OMP “vaginal micronized progesterone (OMP), administered for the induction of withdrawal bleeding” NCT03088046
Known as Oral micronized progesterone Oral micronized progesterone is molecularly identical to human progesterone, a steroid hormone.” NCT01464697
Known as Oral micronized progesterone: Prometrium, Uteroestan “Oral micronized progesterone: Prometrium®, Uteroestan®” NCT00152438
Known as Oral Progesterone “Chinese Herbal Medicine (New "Shoutai Wan", one pack twice daily) + Oral Progesterone (100 mg thrice daily)” NCT02633878