drugset
drugset / Trial / NCT01773772

Progesterone Suppression of Nocturnal LH Increases in Pubertal Girls

NCT01773772 ↗

Phase 1 Completed 14 enrolled University of Virginia Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · collab
RandomizedSingle-groupSingle-blindBasic science

Summary

The purpose of this study is to learn more about how gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) pulses are controlled during puberty. In this study, the investigators aim to discover whether or not giving 2 small doses of progesterone to early pubertal girls will prevent the nighttime increase of GnRH and LH pulses. From the information gathered in this study, the investigators may be able to learn more about how menstrual cycles are normally established in girls during puberty. Ultimately, if these normal processes can be understood, the investigators may be able to better understand abnormalities of puberty.

Timeline

Start
2005-02-08
Primary completion
2009-06-08
Completion
2009-06-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Progesterone Other / unclassified 25 mg Oral
Subject Progesterone Other / unclassified 50 mg Oral

Indications

No indication recorded.