drugset / Trial / NCT06530459

The MUSE Study for Menopausal Arthralgia

NCT06530459

Phase 2/3 Recruiting 100 enrolled National University Hospital, Singapore
RandomizedFactorialOpen-labelTreatment

Summary

The investigators plan to conduct a pilot 4-arm, randomized study comprising the following interventions: muscle strengthening exercises (MSE) alone, estrogen therapy (ET) alone, and a combination of MSE and ET, compared to usual care in women with menopausal arthralgia. The aim of this pilot study is to assess the feasibility, patient acceptability, and patient perspectives and logistics of delivering interventions, and practicability of outcome assessment tools in this 4-arm study over a 12-week period.

Timeline

Start
2024-08-01
Primary completion
2027-04
Completion
2028-04

Drugs

EvaluationDrugModalityDoseRoute
Subject 17-beta estradiol Unknown 1.25 g Topical
Subject 17-beta estradiol Unknown 2.5 g Topical
Subject Progesterone Other / unclassified 200 mg Oral