drugset / Trial / NCT06530459
The MUSE Study for Menopausal Arthralgia
RandomizedFactorialOpen-labelTreatment
Summary
The investigators plan to conduct a pilot 4-arm, randomized study comprising the following interventions: muscle strengthening exercises (MSE) alone, estrogen therapy (ET) alone, and a combination of MSE and ET, compared to usual care in women with menopausal arthralgia. The aim of this pilot study is to assess the feasibility, patient acceptability, and patient perspectives and logistics of delivering interventions, and practicability of outcome assessment tools in this 4-arm study over a 12-week period.
Timeline
- Start
- 2024-08-01
- Primary completion
- 2027-04
- Completion
- 2028-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | 17-beta estradiol | Unknown | 1.25 g | Topical |
| Subject | 17-beta estradiol | Unknown | 2.5 g | Topical |
| Subject | Progesterone | Other / unclassified | 200 mg | Oral |