drugset

drugset / Trial / NCT01126255

Progesterone vs Clobetasol Propionate in Vulvar Lichen Sclerosus

NCT01126255 ↗

Phase 2 Terminated 37 enrolled Insel Gruppe AG, University Hospital Bern University of Bern · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a randomized trial comparing progesterone with conventional clobetasol propionate in patients with vulvar lichen sclerosus.

Timeline

Start: 2011-03
Primary completion: 2014-07
Completion: 2014-07

Publications

Results Gunthert AR, Limacher A, Beltraminelli H, Krause E, Mueller MD, Trelle S, Bobos P, Juni P. Efficacy of topical progesterone versus topical clobetasol propionate in patients with vulvar Lichen sclerosus - A double-blind randomized phase II pilot study. Eur J Obstet Gynecol Reprod Biol. 2022 May;272:88-95. doi: 10.1016/j.ejogrb.2022.03.020. Epub 2022 Mar 10.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Progesterone	Other / unclassified	8 %	Topical
Subject	Progesterone	Other / unclassified	2 g	Topical
Comparator	clobetasol propionate	Small molecule	0.05 %	Topical
Comparator	clobetasol propionate	Small molecule	2 g	Topical

Indications