drugset / Trial / NCT01237535
Luteal Phase Support With Progesterone Versus Estrogen and Progesterone on Pregnancy Rates
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a single center, 3 arms, prospective randomized controlled open study to determine the impact of luteal phase support on pregnancy rates in ovarian stimulation and IUI cycles with recombinant FSH in patients with unexplained infertility and mild male factor. Patients will be randomized into 3 groups: 1. Luteal support with progesterone only (they will received vaginal P gel (Crinone 8% vaginal gel; Serono, Israel) 2. Luteal support with estrogen + progesterone \[(Crinone 8% vaginal gel; Serono, Israel) and Estrofem 4mg\]. 3. No luteal support
Timeline
- Start
- 2011-11
- Primary completion
- 2013-11
- Completion
- 2013-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Estradiol | Other / unclassified | 4 mg | — |
| Subject | Progesterone | Other / unclassified | 8 % | Other |