drugset / Trial / NCT03540225
Vaginal Progesterone for the Prevention of Preterm Birth in Twins
RandomizedFactorialTriple-blindPrevention
Summary
This trial is a randomised, multi-centre, 2 x 2 factorial designed pilot trial with two factors of 200mg vs. 400mg progesterone self-administered daily from 11-14 weeks' gestation vs. 20-24 weeks' gestation, to compare the median gestational age (in days) at delivery between the comparison groups.
Timeline
- Start
- 2020-04
- Primary completion
- 2022-04
- Completion
- 2022-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Progesterone | Other / unclassified | 200 mg | Intravenous |
| Subject | Progesterone | Other / unclassified | 400 mg | Intravenous |