drugset / Trial / NCT00001481

The Role of Hormones in Postpartum Mood Disorders

NCT00001481

Phase 2 Completed 74 enrolled National Institute of Mental Health (NIMH)
Non-randomizedParallel-groupDouble-blindBasic science

Summary

The present protocol is designed to create a "scaled-down" hormonal milieu of pregnancy and the puerperium in order to determine whether it is the abrupt withdrawal of gonadal steroids or the prolonged exposure to gonadal steroids that is associated with mood symptoms.

Timeline

Start
1996-04-26
Primary completion
2024-10-25
Completion
2024-10-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Estradiol Other / unclassified 2 mg Oral
Subject Progesterone Other / unclassified 200 mg Oral
Background Leuprolide Other / unclassified 3.75 mg Intramuscular

Indications