drugset / Trial / NCT00279903
Is Botox Effective in Relieving Pain From Knee Osteoarthritis?
RandomizedParallel-groupDouble-blindTreatment
Summary
Patients with painful knee osteoarthritis will be randomly allocated to one of three groups. Each group will receive a knee injection of: 1) cortisone, 2) low dose Botox, or 3) high dose Botox. Patients will then be followed for 6 months to see if they have significant pain relief or improvement in their activity level after the injection.
Timeline
- Start
- 2005-11
- Primary completion
- 2008-08
- Completion
- 2008-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 100 iu | Other |
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 200 iu | Other |
| Comparator | Methylprednisolone | Other / unclassified | 40 mg | Other |