drugset / Trial / NCT00281944

Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors

NCT00281944 ↗

Phase 1 Completed 42 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial is studying the side effects and best dose of oxaliplatin when given together with leucovorin and fluorouracil in treating young patients with advanced solid tumors. Drugs used in chemotherapy, such as oxaliplatin, leucovorin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells.

Timeline

Start
2005-09
Primary completion
2009-05
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxaliplatin Small molecule — Intravenous
Background Leucovorin Small molecule — Intravenous
Background fluorouracil Small molecule — Intravenous