drugset / Trial / NCT00282178
Double-Blind Randomized Cross-Over Trial Comparing Metabolic Effects of Candesartan, Hydrochlorothiazide and Placebo
Phase 2
Completed
26 enrolled
Umeå University
AstraZeneca · collabSahlgrenska University Hospital · collab
RandomizedCrossoverQuadruple-blindTreatment
Summary
The purpose of this study is to investigate the effect of a 12-week candesartan treatment compared with hydrochlorothiazide on insulin sensitivity assessed with hyperinsulinemic euglycemic clamp.
Timeline
- Start
- 2005-04
- Primary completion
- 2006-03
- Completion
- 2006-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Candesartan | Unknown | 16 mg | — |
| Comparator | Candesartan | Unknown | 32 mg | — |
| Comparator | Hydrochlorothiazide | Unknown | 25 mg | — |
| Comparator | Hydrochlorothiazide | Unknown | 50 mg | — |