Drugs / Candesartan
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Candesartan

Developed for
hypertensive disorder · essential hypertension · cardiovascular disorder · COVID-19 · heart failure · obesity disorder · type 1 diabetes mellitus · type 2 diabetes mellitus
+39 more · atrial fibrillation · cognitive impairment with or without cerebellar ataxia · stroke disorder · alcoholic liver disease · Alzheimer disease · aortic valve stenosis · bipolar depression · cardio-renal syndrome · cocaine dependence · congestive heart failure · depressive disorder · diabetic kidney disease · diastolic heart failure · dilated cardiomyopathy · glucose intolerance · heart disorder · hypertensive heart disease · hypertrophic cardiomyopathy · migraine disorder · migraine with aura · migraine without aura · mitral valve insufficiency · peripheral arterial disease · peripheral neuropathy · pneumonia · symptomatic heart failure · acute coronary syndrome · acute myocardial infarction · Barrett esophagus · chemotherapy-induced toxicity · chronic kidney disease · coronary artery disorder · coronary atherosclerosis · fibrotic liver disease · hepatitis C virus infection · hypoglycemia · methamphetamine dependence · rheumatoid arthritis · tinnitus
Investigated by
AstraZeneca · Takeda · Chong Kun Dang Pharmaceutical · Ullevaal University Hospital · Alvogen Korea · EMS
+85 more · Mayo Clinic · National Heart, Lung, and Blood Institute (NHLBI) · National Institute on Aging (NIA) · Norwegian University of Science and Technology · Novartis · Saitama Medical University · St. Olavs Hospital · Technical University Dresden · University Hospital, Akershus · Yonsei University · Ahn-Gook Pharmaceuticals Co.,Ltd · Asker & Baerum Hospital · Assistance Publique - Hôpitaux de Paris · Augusta University · Australian and New Zealand Intensive Care Research Centre · Baylor College of Medicine · Berry Consultants · Canadian Institutes of Health Research (CIHR) · Charles University, Czech Republic · City Hospitals Sunderland NHS Foundation Trust · Cori Analyticals · Cristina Avendaño Solá · Emory University · Faculty of Pharmaceutical Sciences of Ribeirão Preto - Bioequivalence Center · Fundación Cardiovascular de Colombia · Gachon University Gil Medical Center · Global Coalition for Adaptive Research · Göteborg University · HK inno.N Corporation · Haukeland University Hospital · Hebrew SeniorLife · Helse Ost · Herlev Hospital · Hospital Hietzing · Hospital Sirio-Libanes · Intensive Care National Audit & Research Centre · Kaiser Franz Josef Hospital · Karolinska University Hospital · Kepler University Hospital · Kragerø Tablettproduksjon as, Norway · LabClin Laboratório Clínico · Laboratório de Patologia Clínica Dr. Franceschi Ltda. · Martin Huelsmann · Medical Research Institute of New Zealand · Medical University Innsbruck · Medical University of Graz · Medical University of Vienna · Midas Pharma GmbH · Molde Hospital · Montreal Heart Institute · Nat Intensive Care Surveillance - MORU · National Institute on Drug Abuse (NIDA) · National University Hospital, Singapore · Non-Profit Organaizaion "LINE" · Nordland Hospital · Norwegian Cancer Society · Odense University Hospital · Ottawa Heart Institute Research Corporation · Otto Wagner Hospital · Providence Health & Services · Rambam Health Care Campus · Rikshospitalet University Hospital · Rune Skovgaard Rasmussen · SMZ-Ost Donauspital · Scentryphar Clinical Research · Shin Poong Pharmaceutical Co. Ltd. · Slovak Academy of Sciences · Sorlandet Hospital HF · Southern-Eastern Norway Health Authorities RHF · St George's, University of London · St. Marianna University School of Medicine · Tartu University Hospital · The University of Texas Health Science Center, Houston · Third Military Medical University · all 91 on the full record

Trials 67 · started per year

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199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 02 trials
Phase 0 NCT04430959 Oct 2020 → Jul 2022 bipolar depression The University of Texas Health Science Center, Houston Withdrawn No outcome recorded
Phase 0 NCT03583866 May 2018 → Dec 2025 overdue hypertensive disorder Augusta University Active not recruiting No outcome recorded
Phase 18 trials
Phase 1 NCT04611932 Nov 2020 → Mar 2021 cardiovascular disorder Chong Kun Dang Pharmaceutical Unknown No outcome recorded
Phase 1 NCT04245046 Jan → Feb 2019 Midas Pharma GmbH Completed No outcome recorded
Phase 1 NCT02064621 Jun → Aug 2014 hypertensive disorder Chong Kun Dang Pharmaceutical Completed No outcome recorded
Phase 1 NCT02064556 May → Jul 2014 hypertensive disorder Chong Kun Dang Pharmaceutical Completed No outcome recorded
Phase 1 NCT02079506 Feb 2014 Alvogen Korea Completed No outcome recorded
Phase 1 NCT00905333 Oct → Nov 2008 AstraZeneca Completed No outcome recorded
Phase 1 NCT00310778 Mar 2006 → Mar 2007 Assistance Publique - Hôpitaux de Paris Completed No outcome recorded
Phase 1 NCT02614352 ? → Feb 2016 Ahn-Gook Pharmaceuticals Co.,Ltd Unknown No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT01678794 Feb 2012 → Jun 2016 cardio-renal syndrome Mayo Clinic Completed No outcome recorded
Phase 1/2 NCT00990639 Sep 2005 → Dec 2008 alcoholic liver disease Yonsei University Completed No outcome recorded
Phase 210 trials
Phase 2 NCT07135245 Jan 2026 → Sep 2030 expected Alzheimer disease Rune Skovgaard Rasmussen Not yet recruiting No outcome recorded
Phase 2 NCT06212648 Mar → Nov 2022 essential hypertension Shin Poong Pharmaceutical Co. Ltd. Completed No outcome recorded
Phase 2 NCT04574713 Apr 2021 → Apr 2024 migraine disorder St. Olavs Hospital Completed No outcome recorded
Phase 2 NCT03688633 May 2019 → May 2021 peripheral neuropathy University Hospital, Limoges Terminated No outcome recorded
Phase 2 NCT02646982 Jun 2016 → Aug 2020 cognitive impairment with or without cerebellar ataxia Emory University Completed No outcome recorded
Phase 2 NCT02206165 Mar 2014 → Apr 2015 essential hypertension Chong Kun Dang Pharmaceutical Unknown No outcome recorded
Phase 2 NCT01938664 Jan 2013 → Jul 2016 cocaine dependence Baylor College of Medicine Terminated No outcome recorded
Phase 2 NCT01434134 Sep 2011 → Sep 2014 breast cancer, heart failure University Hospital, Akershus Completed No outcome recorded
Phase 2 NCT00605072 Jan 2008 → Dec 2011 cognitive impairment with or without cerebellar ataxia, hypertensive disorder University of Southern California Completed No outcome recorded
Phase 2 NCT00430833 hypertrophic cardiomyopathy Charles University, Czech Republic Unknown No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT04351724 Apr 2020 → Dec 2021 COVID-19 Medical University of Vienna Unknown No outcome recorded
Phase 2/3 NCT00884663 Apr 2009 → Mar 2012 migraine with aura, migraine without aura Norwegian University of Science and Technology Completed No outcome recorded
Phase 319 trials
Phase 3 NCT05321875 Jun 2022 → Jun 2026 overdue dilated cardiomyopathy Cristina Avendaño Solá Recruiting No outcome recorded
Phase 3 NCT04591210 Jan 2021 → Dec 2024 COVID-19, cardiovascular disorder Ottawa Heart Institute Research Corporation Completed No outcome recorded
Phase 3 NCT04606563 Oct 2020 → Apr 2022 COVID-19 University of British Columbia Terminated No outcome recorded
Phase 3 NCT02969265 May 2017 → Jul 2018 hypertensive disorder Takeda Withdrawn No outcome recorded
Phase 3 NCT02521233 Nov 2016 → May 2017 essential hypertension EMS Withdrawn No outcome recorded
Phase 3 NCT02521246 Nov 2016 → May 2017 essential hypertension EMS Withdrawn No outcome recorded
Phase 3 NCT02735707 Apr 2016 → Feb 2026 overdue pneumonia UMC Utrecht Recruiting No outcome recorded
Phase 3 NCT02770261 Dec 2015 → Aug 2016 hyperlipidemia, hypertensive disorder Alvogen Korea Completed No outcome recorded
Phase 3 NCT02651870 Apr 2015 → Feb 2016 hypertensive disorder Chong Kun Dang Pharmaceutical Completed No outcome recorded
Phase 3 NCT00867490 Mar → Aug 2009 hypertensive disorder Novartis Completed No outcome recorded
Phase 417 trials
Phase 4 NCT05637853 Oct 2022 → Aug 2024 overdue symptomatic heart failure Göteborg University Active not recruiting No outcome recorded
Phase 4 NCT05535595 Nov 2019 → Aug 2021 hypertensive disorder Yonsei University Completed No outcome recorded
Phase 4 NCT03231982 Apr 2017 → Apr 2019 essential hypertension HK inno.N Corporation Unknown No outcome recorded
Phase 4 NCT02817360 Feb 2016 → Dec 2025 overdue heart disorder, type 2 diabetes mellitus Martin Huelsmann Recruiting No outcome recorded
Phase 4 NCT01794455 May 2013 → Mar 2015 depressive disorder, hypertensive disorder Vanderbilt University Terminated No outcome recorded
Phase 4 NCT01682564 Jan 2012 → Oct 2014 congestive heart failure, hypertensive disorder Chong Kun Dang Pharmaceutical Completed No outcome recorded
Phase 4 NCT00538486 Feb 2008 → Jun 2009 hypertensive disorder, obesity disorder Third Military Medical University Completed No outcome recorded
Phase 4 NCT00564057 Sep 2007 → Sep 2009 HIV infectious disease, hypertensive disorder University of Insubria Unknown No outcome recorded
Phase 4 NCT00400582 Nov 2006 → Apr 2010 heart failure Montreal Heart Institute Completed No outcome recorded
Phase 4 NCT00775814 Oct 2006 → Sep 2008 hypertensive disorder, obesity disorder Takeda Completed No outcome recorded
Phase not applicable7 trials
NCT01444833 Oct 2008 → Mar 2009 essential hypertension Slovak Academy of Sciences Unknown No outcome recorded
NCT00288717 Feb 2006 → Sep 2007 hypertensive disorder Saitama Medical University Unknown No outcome recorded
NCT00154037 Oct 2005 → Sep 2006 Technical University Dresden Completed No outcome recorded
NCT00154050 May 2004 → Jul 2006 peripheral arterial disease Technical University Dresden Completed No outcome recorded
NCT00141583 Apr 2004 → Oct 2006 essential hypertension St George's, University of London Terminated No outcome recorded
NCT00320970 Aug 2002 → Sep 2004 diabetic kidney disease, hypertensive disorder Providence Health & Services Completed No outcome recorded
NCT00530595 cardiovascular disorder Saitama Medical University Completed No outcome recorded
Also used as a comparator or background therapy in 46 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT02879721 Comparator Oct 2009 → Dec 2012 Barrett esophagus Göteborg University Completed No outcome recorded
Phase 13 trials
Phase 1 NCT01976572 Comparator Oct 2013 → Jan 2014 chronic kidney disease, hyperphosphatemia Tanabe Pharma Corporation Completed No outcome recorded
Phase 1 NCT01806311 Comparator Dec 2012 → Aug 2013 hypertensive disorder HanAll BioPharma Co., Ltd. Completed No outcome recorded
Phase 1 NCT01062451 Comparator May 2009 → Nov 2013 methamphetamine dependence, substance abuse Baylor College of Medicine Completed No outcome recorded
Phase 25 trials
Phase 2 NCT07064525 Comparator Dec 2024 → Dec 2025 overdue advanced heart failure, diabetes mellitus, essential hypertension, moderate heart failure Shin Poong Pharmaceutical Co. Ltd. Enrolling by invitation No outcome recorded
Phase 2 NCT03640312 Comparator Aug 2019 → May 2022 hypertensive disorder Washington University School of Medicine Completed No outcome recorded
Phase 2 NCT01984164 Comparator Aug 2014 → Dec 2018 cognitive impairment with or without cerebellar ataxia, hypertensive disorder Emory University Completed No outcome recorded
Phase 2 NCT00282178 Comparator Apr 2005 → Mar 2006 hypertensive disorder, obesity disorder Umeå University Completed No outcome recorded
Phase 2 NCT00930995 Comparator hepatitis C virus infection Kaiser Permanente Withdrawn No outcome recorded
Phase 311 trials
Phase 3 NCT06646354 Comparator Apr → May 2025 overdue essential hypertension, hyperlipoproteinemia Hyundai Pharm Enrolling by invitation No outcome recorded
Phase 3 NCT03770936 Comparator Oct 2018 → Oct 2026 expected fibrotic liver disease Tanta University Recruiting No outcome recorded
Phase 3 NCT03770702 Comparator Oct 2018 → Dec 2025 overdue rheumatoid arthritis Tanta University Recruiting No outcome recorded
Phase 3 NCT00699452 Comparator May 2009 → Dec 2012 aortic valve stenosis University of Helsinki Unknown No outcome recorded
Phase 3 NCT00644475 Comparator Mar 2008 essential hypertension University of Pavia Unknown No outcome recorded
Phase 422 trials
Phase 4 NCT07687160 Comparator Sep 2026 → Feb 2028 expected hypertensive disorder Ottawa Hospital Research Institute Not yet recruiting No outcome recorded
Phase 4 NCT07655440 Comparator Jul 2026 → Jul 2031 expected migraine disorder, tinnitus, vestibular disorder Stanford University Not yet recruiting No outcome recorded
Phase 4 NCT07513883 Background Mar 2026 → Sep 2028 expected heart failure Ziekenhuis Oost-Limburg Recruiting No outcome recorded
Phase 4 NCT05169021 Comparator Dec 2021 → Dec 2024 overdue stroke disorder Beijing Tiantan Hospital Not yet recruiting No outcome recorded
Phase 4 NCT04394117 Comparator Jun 2020 → Nov 2021 COVID-19 The George Institute Completed No outcome recorded
Phase not applicable4 trials
NCT04429633 Comparator Jul 2019 → Jul 2022 breast cancer, chemotherapy-induced toxicity Samsung Medical Center Unknown No outcome recorded
NCT01116180 Comparator Apr 2010 → Aug 2012 hypoglycemia, type 1 diabetes mellitus Louise Faerch Completed No outcome recorded
NCT00863980 Comparator Apr 2009 → Jul 2013 acute coronary syndrome, acute myocardial infarction, hypertensive disorder Kyoto Prefectural University of Medicine Terminated No outcome recorded
NCT00684489 Comparator Sep 2003 → Mar 2005 essential hypertension Medical University of South Carolina Completed No outcome recorded

Press releases naming this drug 3 releases

DateIssuerRelease
2014-05-16 Takeda Takeda and ASKA Sign Distribution Agreement of Candesartan "ASKA", Treatment for Hypertension takeda.com
2014-04-03 Takeda JPMA's Sanctions Against Takeda Regarding Promotional Activities for Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) takeda.com
2014-03-07 Takeda Takeda Announces the Appointment of Third-party Investigators Regarding Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) takeda.com

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 114 sources stand behind the page.

FieldValueCited text
Known as Candesartan “The dosages were SPC1001 High (4/2.5/1.25 mg), SPC1001 Mid1 (2.67/1.67/0.83 mg), SPC1001 Mid2 (4/1.25/1.25 mg), SPC1001 Low (2/1.25/0.625 mg), SPC3001 (candesartan 8 mg),...” PMID 41162308 Oct 2025
112

“To evaluate the efficacy and safety of amlodipine besylate and candesartan cilexetil administered in a fixed-dose combination tablet versus co-administered as their separate...” NCT03231982

“One of ARBs(Valsartan, Olmesartan, Candesartan, Telmisartan, Fimasartan, Losartan and Irbesartan) and one of statins(Rosuvastatin, Atorvastatin, Pitavastatin, Simvastatin,...” NCT04061824

“Administration of candesartan to patients with biomarker-confirmed initial-stage Alzheimer's disease will decrease levels of amyloid markers, improve cognitive function, and...” NCT07135245

“Efficacy and Safety of a Fixed-Dose Combination of Candesartan and Rosuvastatin on Blood Pressure and Cholesterol in Patients With Hypertension and Hypercholesterolemia” PMID 31307833 Jul 2019

“Angiotensin II receptor antagonists ,these medicines have names that end in "sartan".For examples:losartan,candesartan,irbesartan,olmesartan,telmisartan,valsartan” NCT01377285

“Participants received either a quadpill of candesartan 2 mg, amlodipine 1.25 mg, indapamide 0.625 mg, and bisoprolol 2.5 mg or candesartan 8 mg for 12 weeks.” PMID 38584159 Apr 2024

“If the patient is intolerant to either of these, an angiotensin receptor blocker (ARB)(Candesartan, Losartan, Valsartan) will be introduced.” NCT05637853

“The aim of this study was to compare the pharmacokinetics (PKs) of candesartan, amlodipine, and atorvastatin FDC versus separate tablets.” PMID 41970000 Mar 2026

Candesartan/Hydrochlorothiazide(Candemore Plus® Tab) Versus Candesartan/Amlodipine(Cantabell® Tab) in Hypertensive Patients” NCT04521023

“The study recommends physicians to select evidence-based ARBs such as candesartan or valsartan or losartan.” NCT04591210

“fixed-dose triple combination therapy (SPC1001 Low) of candesartan, amlodipine, and indapamide” NCT07064525

Candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, valsartan” NCT04330300

“ARB (second line alternative to ACEi): valsartan, losartan or candesartanNCT07513883

“trandolapril, candesartan, eprosartan, irbesartan, losartan” NCT00684489

“TCV-116CCB (Candesartan 8 mg Plus Amlodipine 5 mg)” NCT02969265

candesartan: 32 mg/d→16 mg/d→8 mg/d→4 m/d→stop” NCT02200822

candesartan 8 mg/d after genotyping” NCT05535595

candesartan (Atacand)” NCT00000620

“Add candesartan 4mg;” NCT05169021

Candesartan 32mg/d” NCT02817360

CandesartanNCT02735707

CandesartanNCT03770702

CandesartanNCT00741585

NCT00459771

NCT01827202

NCT03770936

NCT07655440

NCT00310778

NCT04574713

NCT00356395

NCT01444833

NCT01984164

NCT00319202

NCT04351724

NCT01794455

NCT01062451

NCT00150631

NCT00120003

NCT00320970

NCT02614352

NCT00634712

NCT00699452

NCT03583866

NCT01938664

NCT00530595

NCT00905333

NCT00930995

NCT00294775

NCT03688633

NCT00154037

NCT00154050

NCT00232882

NCT01629225

NCT01162902

NCT02206165

NCT02521246

NCT02521233

NCT04606563

NCT00400582

NCT00391846

NCT04430959

NCT00192803

NCT00430833

NCT01976572

NCT00282178

NCT00538486

NCT00990639

NCT00288717

NCT04429633

NCT07687160

NCT00884663

NCT00634400

NCT00139386

NCT00863980

NCT00141583

NCT00634309

NCT00867490

NCT02261116

NCT00541853

NCT00328302

NCT00252694

NCT01806311

NCT01434134

NCT00252720

NCT00235287

NCT00775814

NCT00468923

NCT02079506

NCT00775840

NCT00360178

NCT02651870

NCT02879721

NCT06646354

NCT00607672

NCT02064621

NCT00252733

NCT02646982

NCT00644475

NCT00564057

NCT04245046

NCT01116180

NCT00587470

NCT00348686

NCT05321875

NCT00605072

NCT01678794

NCT00130975

NCT04394117

NCT00843154

NCT00108706

NCT03640312

NCT02064556

Known as Atacand “treatment with candesartan (Atacand®) 8 mg daily is initiated” NCT00294775
Known as Blopress Blopress (Candesartan)” NCT00863980
Known as Candemore ClinicalTrials.gov intervention name — accepted as the source's own label NCT01682564
Known as candesartan (Atacand) candesartan (Atacand)NCT00000620
Known as candesartan cilexetil “Study to determine the potential pharmacokinetic interaction of candesartan cilexetil, atorvastatin as atorvastatin calcium trihydrate and amlodipine as amlodipine besilate at...” NCT04245046
2

“The subjects receive treatment with either the AT1-antagonist candesartan cilexetil, 16 mg daily or placebo for one year.” NCT00150631

“Effects of Candesartan Cilexetil (Candesartan) on Diabetic Retinopathy in Type 2 Diabetic Patients With Retinopathy.” NCT00252694

Known as Candesartan cilexitil Candesartan cilexitil tablets, 16 mg once daily” NCT00884663
Known as CND “The aim of this study was to evaluate the blood pressure-lowering and cholesterol-lowering effects of a fixed-dose combination therapy using candesartan (CND)/rosuvastatin...” PMID 31307833 Jul 2019
Known as SPC3001 “The dosages were SPC1001 High (4/2.5/1.25 mg), SPC1001 Mid1 (2.67/1.67/0.83 mg), SPC1001 Mid2 (4/1.25/1.25 mg), SPC1001 Low (2/1.25/0.625 mg), SPC3001 (candesartan 8 mg),...” PMID 41162308 Oct 2025
Action Inhibit “AT1 receptor blockade with candesartan in acute stroke” NCT00120003
Route Oral “Candesartan will be given orally (4 weeks 8mg/d, titrated to 16 mg/d for another 4 weeks)” NCT00154037