drugset / Trial / NCT05321875

Early Treatment With Candesartan vs Placebo in Genetic Carriers of Dilated Cardiomyopathy (EARLY-GENE Trial)

NCT05321875

Phase 3 Recruiting 320 enrolled Cristina Avendaño Solá
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Prospective, multicenter, randomized, placebo-controlled, double-blind clinical trial to evaluate safety and efficacy of candesartan in the prevention of the development of Dilated Cardiomyopathy (DCM) in genetic carriers of a DCM-causing variant without disease expression (asymptomatic)

Timeline

Start
2022-06-02
Primary completion
2026-06-02
Completion
2026-06-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Candesartan Unknown 32 mg Oral