drugset / Trial / NCT03583866
Adiposity and Endothelin Receptor Function
Phase 0
Active not recruiting
25 enrolled
Augusta University
National Heart, Lung, and Blood Institute (NHLBI) · collab
RandomizedCrossoverDouble-blindTreatment
Summary
Elevated levels of ET-1 have been implicated in cardiovascular disease and some forms of hypertension. Due to the strong, positive correlation between obesity and hypertension, the present study will explore the contribution of adiposity in ETB receptor function and aim to elucidate if ETB receptor dysfunction is a major contributor to hypertension in obesity.
Timeline
- Start
- 2018-05-21
- Primary completion
- 2025-12
- Completion
- 2026-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Candesartan | Unknown | 16 mg | — |