drugset / Trial / NCT00284128
AVE7688 in Patients With Mild to Moderate Blood Pressure
RandomizedParallel-groupDouble-blindTreatment
Summary
The primary objective is to assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change from baseline in trough diastolic blood pressure at the end of week 12. The secondary objectives are: * To assess the antihypertensive efficacy of 4 different AVE 7688 doses on the change from baseline in trough systolic blood pressure at the end of week 12 * To compare the percentages of responders after 12 week of treatment * To evaluate the long term safety and tolerability of AVE 7688 with particular attention to angioedema
Timeline
- Start
- 2005-12
- Primary completion
- 2008-03
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ILEPATRIL | Small molecule | 2.5 mg | Oral |
| Subject | ILEPATRIL | Small molecule | 10 mg | Oral |
| Subject | ILEPATRIL | Small molecule | 35 mg | Oral |
| Subject | ILEPATRIL | Small molecule | 50 mg | Oral |
| Subject | Losartan | Other / unclassified | 100 mg | Oral |