Drugs / Losartan
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Losartan

Other / unclassified targets AGTR1, TGFB1 via inhibition

Developed for
hypertensive disorder · essential hypertension · diabetic kidney disease · type 2 diabetes mellitus · COVID-19 · proteinuria · Marfan syndrome · chronic kidney disease
+97 more · diabetes mellitus · IgA glomerulonephritis · malignant pancreatic neoplasm · sickle cell disease · acute respiratory distress syndrome · cardiovascular disorder · cystic fibrosis · hyperlipidemia · obesity disorder · pancreatic adenocarcinoma · post-traumatic stress disorder · symptomatic heart failure · aortic valve insufficiency · atherosclerosis · breast cancer · chronic bronchitis · congestive heart failure · eosinophilic esophagitis · glucose intolerance · heart disorder · heart failure · HIV infectious disease · ischemic stroke · osteoarthritis, knee · pancreatic ductal adenocarcinoma · pneumonia · prediabetes syndrome · pulmonary fibrosis · radiation-induced disorder · refractory malignant neoplasm · acute urate nephropathy · alcoholic liver cirrhosis · ankylosis · aorta coarctation · aortic valve disorder · arthropathy · articular cartilage disorder · atrial fibrillation · central sleep apnea syndrome · chemotherapy-induced neuropathy · chemotherapy-induced oral mucositis · chronic hepatitis C virus infection · diabetic macular edema · early onset hypertension · fatty liver disease · fibrotic liver disease · frozen shoulder · gastrointestinal mucositis · glioblastoma · glomerulonephritis · head and neck squamous cell carcinoma · hepatocellular carcinoma · hypertensive heart disease · hypertensive nephropathy · hypertrophic cardiomyopathy · idiopathic pulmonary fibrosis · impaired renal function disease · keloid · kidney disorder · metabolic dysfunction-associated steatohepatitis · metabolic syndrome X · metastatic malignant neoplasm in the brain · NAFLD1 · nonobstructive coronary artery disease · obstructive sleep apnea syndrome · Orthocoronavirinae infectious disease · osteoarthritis, hip · osteosarcoma · postinflammatory pulmonary fibrosis · precancerous condition · preeclampsia · primary pulmonary vein stenosis · pulmonary emphysema · pure autonomic failure · resistant hypertension · stroke disorder · thoracic aortic aneurysm · type 1 diabetes mellitus · acute kidney injury · acute pancreatitis · cardiomyopathy · cerebrovascular disorder · corneal disorder · hyperglycemia · inflammation of heart layer · long COVID-19 · mucopolysaccharidosis type 4A · mucopolysaccharidosis type 6 · muscular atrophy · nephrolithiasis · peripheral arterial disease · postoperative ventricular dysfunction · postural orthostatic tachycardia syndrome · primary hyperoxaluria · pulmonary hypertension · tetralogy of fallot · urinary tract obstruction
Investigated by
Organon and Co · Merck Sharp & Dohme LLC · Hanmi Pharmaceutical Company Limited · University of Electronic Science and Technology of China · University of Oxford · Massachusetts General Hospital
+265 more · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Children's Hospital Medical Center, Cincinnati · National Cancer Institute (NCI) · National Heart, Lung, and Blood Institute (NHLBI) · University of Kansas Medical Center · Seoul National University Hospital · Shanghai Jiao Tong University School of Medicine · Steadman Philippon Research Institute · University of Minnesota · Boehringer Ingelheim · NYU Langone Health · National Institute for Health Research, United Kingdom · University of British Columbia · University of California, San Francisco · Vanderbilt University · Washington University School of Medicine · Anna Stanhewicz, PhD · Assaf-Harofeh Medical Center · Bristol-Myers Squibb · Canadian Institutes of Health Research (CIHR) · Centre for Chronic Disease Control, India · Chonbuk National University Hospital · Emory University · Fifth Affiliated Hospital, Sun Yat-Sen University · Flight Attendant Medical Research Institute · Göteborg University · Johns Hopkins University · Lustgarten Foundation · Mayo Clinic · Mclean Hospital · Merck Frosst Canada Ltd. · Michigan State University · Ministry of Food and Drug Safety, Korea · National Center for Advancing Translational Sciences (NCATS) · National Center for Complementary and Integrative Health (NCCIH) · National Institute of Allergy and Infectious Diseases (NIAID) · National Institute on Aging (NIA) · National Taiwan University Hospital · OHSU Knight Cancer Institute · Oregon Health and Science University · Pfizer · RemediumOne · Sankyo Pharma Gmbh · Seoul National University Bundang Hospital · São Paulo Research Foundation · Teva Pharmaceuticals USA · Texas Health Resources · The George Institute · United States Department of Defense · University of Alabama at Birmingham · University of Florida · University of Miami · University of Pavia · University of South Florida · University of Southern Denmark · University of Texas Southwestern Medical Center · Washington State University · AHEPA University Hospital · Aarhus University Hospital · Abbott · Academy of Finland · Actuate Therapeutics Inc. · Affiliated Hospital of Qinghai University · Agentschap voor Innovatie door Wetenschap en Technologie · Ain Shams University · Ajou University School of Medicine · Aleksi Tornio · Alicia Gerke · Alnylam Pharmaceuticals · American Cancer Society, Inc. · American Heart Association · Amsterdam UMC, location VUmc · Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi · Arthroscopy Association of North America · all 271 on the full record

Regulatory milestones approvals, filings & regulatory actions · 5 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (4) US (FDA) COZAAR 1995-12-29 – 2004-03-11 fda.gov
Approved US (FDA) COZAAR 1995-04-14 fda.gov

Trials 250 · started per year

today
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 015 trials
Phase 0 NCT07017023 Jul 2025 → Dec 2026 expected University of Oxford Recruiting No outcome recorded
Phase 0 NCT06693960 Sep 2024 → Dec 2026 expected Washington State University Recruiting No outcome recorded
Phase 0 NCT06624904 Aug 2024 → Oct 2025 overdue CGF1 University of Oxford Recruiting No outcome recorded
Phase 0 NCT06628154 Aug 2024 → Jul 2025 overdue University of Oxford Recruiting No outcome recorded
Phase 0 NCT06636812 Mar 2024 → Dec 2025 overdue University of Oxford Recruiting No outcome recorded
Phase 0 NCT05607017 Sep 2023 → Oct 2025 breast cancer, radiation-induced disorder Massachusetts General Hospital Completed No outcome recorded
Phase 0 NCT05576155 Oct 2022 → Feb 2023 Anna Stanhewicz, PhD Completed No outcome recorded
Phase 0 NCT03435939 Feb 2022 → Sep 2025 cystic fibrosis University of Kansas Medical Center Completed No outcome recorded
Phase 0 NCT05365893 Oct 2021 → Dec 2025 overdue pancreatic ductal adenocarcinoma Fox Chase Cancer Center Active not recruiting No outcome recorded
Phase 0 NCT05132712 Oct 2021 → Sep 2022 Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi Unknown No outcome recorded
Phase 133 trials
Phase 1 NCT07300670 Mar → May 2026 overdue Aleksi Tornio Recruiting No outcome recorded
Phase 1 NCT06930872 Jun → Oct 2025 Harmony Biosciences Management, Inc. Completed No outcome recorded
Phase 1 NCT06831864 Feb → May 2025 symptomatic heart failure Washington University School of Medicine Completed No outcome recorded
Phase 1 NCT06211335 Dec 2023 → Dec 2026 expected head and neck squamous cell carcinoma University of California, Davis Recruiting No outcome recorded
Phase 1 NCT04201197 Nov 2020 → Mar 2022 Johns Hopkins University Completed No outcome recorded
Phase 1 NCT04504045 Sep 2020 → May 2022 type 2 diabetes mellitus University of Southern Denmark Terminated No outcome recorded
Phase 1 NCT04335123 Apr → Jun 2020 COVID-19 University of Kansas Medical Center Completed No outcome recorded
Phase 1 NCT03878524 Apr → Dec 2020 acute myeloid leukemia, atypical chronic myeloid leukemia, BCR-ABL1 negative, blast phase chronic myelogenous leukemia, BCR-ABL1 positive, castration-resistant prostate carcinoma +14 OHSU Knight Cancer Institute Terminated No outcome recorded
Phase 1 NCT03900793 Aug 2019 → Aug 2027 expected osteosarcoma University of Colorado, Denver Recruiting No outcome recorded
Phase 1 NCT04106856 Aug 2019 → Dec 2024 pancreatic ductal adenocarcinoma University of Utah Completed No outcome recorded
Phase 1/29 trials
Phase 1/2 NCT05893108 Mar → Sep 2024 keloid Yuni Eka Anggraini Unknown No outcome recorded
Phase 1/2 NCT06143566 Mar 2024 → Sep 2027 expected hypertensive disorder, type 2 diabetes mellitus University of Texas Southwestern Medical Center Recruiting No outcome recorded
Phase 1/2 NCT06108063 Mar 2024 → Jun 2027 expected osteoarthritis, knee Steadman Philippon Research Institute Recruiting No outcome recorded
Phase 1/2 NCT04815902 May 2021 → Feb 2025 osteoarthritis, knee Steadman Philippon Research Institute Unknown No outcome recorded
Phase 1/2 NCT04212650 Aug → Dec 2020 articular cartilage disorder, osteoarthritis, hip Steadman Philippon Research Institute Terminated No outcome recorded
Phase 1/2 NCT02769130 May 2016 → May 2021 primary pulmonary vein stenosis The Hospital for Sick Children Suspended No outcome recorded
Phase 1/2 NCT01384591 Jul 2011 → May 2015 The University of Texas Medical Branch, Galveston Completed No outcome recorded
Phase 1/2 NCT01086722 Feb 2010 → Feb 2013 morbid obesity Hospital del Mar Medical Research Institute (IMIM) Completed No outcome recorded
Phase 1/2 NCT00467831 Apr 2007 → Nov 2012 Hermansky-Pudlak syndrome, oculocutaneous albinism, platelet storage pool deficiency, pulmonary fibrosis National Human Genome Research Institute (NHGRI) Terminated No outcome recorded
Phase 245 trials
Phase 2 NCT07265739 Aug 2026 → Dec 2027 expected refractory malignant neoplasm Massachusetts General Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06933706 Oct 2025 → Sep 2029 expected Brigham and Women's Hospital Recruiting No outcome recorded
Phase 2 NCT06364176 Jun 2024 → May 2027 expected cystic fibrosis University of Kansas Medical Center Recruiting No outcome recorded
Phase 2 NCT06135493 Dec 2023 → Mar 2025 chemotherapy-induced neuropathy Future University in Egypt Completed No outcome recorded
Phase 2 NCT05637216 Aug 2023 → Aug 2027 expected radiation-induced disorder Shaw Cancer Center Active not recruiting No outcome recorded
Phase 2 NCT05871333 Jul 2023 → Jun 2024 chemotherapy-induced oral mucositis, colorectal cancer, gastrointestinal mucositis Ain Shams University Unknown No outcome recorded
Phase 2 NCT05861336 Jun 2023 → Dec 2024 malignant pancreatic neoplasm Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS Withdrawn No outcome recorded
Phase 2 NCT05331144 Oct 2022 → Jun 2027 expected hereditary dementia, hypertensive disorder, subjective cognitive decline Rong Zhang Recruiting No outcome recorded
Phase 2 NCT05370599 Apr 2022 → Jan 2026 hypertensive disorder University of California, San Francisco Terminated No outcome recorded
Phase 2 NCT05077800 Mar 2022 → Dec 2026 expected pancreatic adenocarcinoma Colin D. Weekes, M.D., PhD Active not recruiting No outcome recorded
Phase 2/36 trials
Phase 2/3 NCT04349410 Apr → Sep 2020 COVID-19 The Camelot Foundation Completed No outcome recorded
Phase 2/3 NCT04328012 Apr 2020 → Jul 2021 Orthocoronavirinae infectious disease Bassett Healthcare Terminated No outcome recorded
Phase 2/3 NCT02913664 Feb 2017 → Nov 2021 hypertensive disorder, subjective cognitive decline University of Texas Southwestern Medical Center Completed No outcome recorded
Phase 2/3 NCT02410005 Oct 2014 → Sep 2015 diabetic kidney disease Weill Cornell Medical College in Qatar Terminated No outcome recorded
Phase 2/3 NCT00981747 Sep 2009 → Dec 2016 idiopathic pulmonary fibrosis, pulmonary fibrosis Alicia Gerke Terminated No outcome recorded
Phase 2/3 NCT00284128 Dec 2005 → Mar 2008 hypertensive disorder Sanofi Completed No outcome recorded
Phase 345 trials
Phase 3 NCT07569640 Jun 2026 → Dec 2028 expected symptomatic heart failure Washington University School of Medicine Not yet recruiting No outcome recorded
Phase 3 NCT06150560 Apr 2024 → Jun 2028 expected aorta coarctation, hypertensive disorder Mayo Clinic Recruiting No outcome recorded
Phase 3 NCT04927299 Jun 2022 → Aug 2023 essential hypertension Laboratorios Silanes S.A. de C.V. Completed No outcome recorded
Phase 3 NCT04591210 Jan 2021 → Dec 2024 COVID-19, cardiovascular disorder Ottawa Heart Institute Research Corporation Completed No outcome recorded
Phase 3 NCT04606563 Oct 2020 → Apr 2022 COVID-19 University of British Columbia Terminated No outcome recorded
Phase 3 NCT04343001 Oct 2020 → Apr 2021 COVID-19 London School of Hygiene and Tropical Medicine Withdrawn No outcome recorded
Phase 3 NCT01620788 Nov 2019 → Jul 2023 hypertensive disorder EMS Suspended No outcome recorded
Phase 3 NCT03357653 Jan 2018 → Dec 2021 IgA glomerulonephritis Ewha Womans University Unknown No outcome recorded
Phase 3 NCT02735707 Apr 2016 → Feb 2026 overdue pneumonia UMC Utrecht Recruiting No outcome recorded
Phase 3 NCT02232776 Oct 2014 → Dec 2016 IgA glomerulonephritis Seoul National University Hospital Completed No outcome recorded
Phase 460 trials
Phase 4 NCT07135687 Aug 2026 → Oct 2028 expected Rush University Medical Center Not yet recruiting No outcome recorded
Phase 4 NCT07704658 Jun 2026 → Jul 2027 expected non-small cell lung carcinoma, thyroid cancer Rigel Pharmaceuticals Recruiting No outcome recorded
Phase 4 NCT07160361 Oct 2025 → Dec 2028 expected hepatocellular carcinoma Second Affiliated Hospital of Xi'an Jiaotong University Not yet recruiting No outcome recorded
Phase 4 NCT07099859 Jul 2025 → Jul 2029 expected aortic valve insufficiency, congestive heart failure Vitor Emer Egypto Rosa Recruiting No outcome recorded
Phase 4 NCT06333522 Jul 2024 → Jan 2026 arthropathy NYU Langone Health Withdrawn No outcome recorded
Phase 4 NCT05157464 Sep 2023 → Dec 2024 ankylosis NYU Langone Health Withdrawn No outcome recorded
Phase 4 NCT05637853 Oct 2022 → Aug 2024 overdue symptomatic heart failure Göteborg University Active not recruiting No outcome recorded
Phase 4 NCT05402397 Jul 2022 → Dec 2023 acute urate nephropathy Hospital General de Niños Pedro de Elizalde Completed No outcome recorded
Phase 4 NCT04715568 Mar 2021 → Dec 2026 expected hypertensive disorder University of California, San Francisco Recruiting No outcome recorded
Phase 4 NCT04238702 Nov 2020 → Sep 2021 diabetic kidney disease, type 2 diabetes mellitus Amsterdam UMC, location VUmc Completed No outcome recorded
Phase not applicable37 trials
NCT07513350 Jan → Nov 2026 expected frozen shoulder Istanbul University Recruiting No outcome recorded
NCT06491940 Aug 2024 → Jul 2025 overdue proteinuria RESnTEC, Institute of Research Not yet recruiting No outcome recorded
NCT06329076 Mar 2024 → Jun 2025 University of Electronic Science and Technology of China Unknown No outcome recorded
NCT06329050 Mar 2024 → Jun 2025 University of Electronic Science and Technology of China Unknown No outcome recorded
NCT04604756 Oct 2020 → Dec 2021 University of Electronic Science and Technology of China Unknown No outcome recorded
NCT04606225 Oct 2020 → Dec 2021 University of Electronic Science and Technology of China Unknown No outcome recorded
NCT04604938 Oct 2020 → Dec 2021 University of Electronic Science and Technology of China Unknown No outcome recorded
NCT04606212 Oct 2020 → Dec 2021 University of Electronic Science and Technology of China Unknown No outcome recorded
NCT05828940 Oct 2019 → Mar 2022 post-traumatic stress disorder University of Oxford Completed No outcome recorded
NCT03604003 Nov 2018 → Jun 2021 chronic kidney disease Fifth Affiliated Hospital, Sun Yat-Sen University Unknown No outcome recorded
Also used as a comparator or background therapy in 138 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 04 trials
Phase 0 NCT06796660 Background Sep 2025 → Dec 2027 expected chronic kidney disease Liu Zhanghong Not yet recruiting No outcome recorded
Phase 0 NCT02704494 Background Mar 2016 → Feb 2017 diabetic kidney disease Shiraz University of Medical Sciences Completed No outcome recorded
Phase 0 NCT01210430 Comparator Jul 2010 → Jun 2015 postural orthostatic tachycardia syndrome New York Medical College Completed No outcome recorded
Phase 0 NCT00720577 Comparator Dec 2005 → Jul 2007 peripheral arterial disease Medtronic Endovascular Completed No outcome recorded
Phase 110 trials
Phase 1 NCT05090449 Comparator May 2019 → Apr 2020 Laboratorios Silanes S.A. de C.V. Completed No outcome recorded
Phase 1 NCT04049734 Comparator Jan 2015 → Jan 2017 acute pancreatitis Ain Shams University Completed No outcome recorded
Phase 1 NCT02166398 Comparator Jun → Oct 2014 Korea United Pharm. Inc. Completed No outcome recorded
Phase 1 NCT01570569 Comparator Jan → Mar 2011 Inje University Completed No outcome recorded
Phase 1 NCT01187862 Background Jul 2010 → Feb 2011 University Hospital, Basel, Switzerland Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02263729 Comparator Aug 2016 → Dec 2022 James J. Irrgang Terminated No outcome recorded
Phase 216 trials
Phase 2 NCT05212597 Comparator Jan 2022 → Dec 2023 aortic valve insufficiency Samsung Medical Center Unknown No outcome recorded
Phase 2 NCT03897868 Comparator Mar 2019 → Feb 2020 essential hypertension Hanmi Pharmaceutical Company Limited Completed No outcome recorded
Phase 2 NCT03632213 Comparator Nov 2018 → May 2023 mucopolysaccharidosis type 4A, mucopolysaccharidosis type 6 Hospital de Clinicas de Porto Alegre Unknown No outcome recorded
Phase 2 NCT03467217 Comparator Oct 2018 → Jun 2020 NAFLD1 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Terminated No outcome recorded
Phase 2 NCT03295734 Comparator May 2018 → Sep 2024 hypertensive disorder University of Alabama at Birmingham Completed No outcome recorded
Phase 2/33 trials
Phase 2/3 NCT07586371 Comparator Apr → Jul 2026 overdue diabetes mellitus, proteinuria Dr Mudassar Saeed Pansota Active not recruiting No outcome recorded
Phase 2/3 NCT04078711 Background Sep 2019 → Jun 2021 essential hypertension Jiangsu Province Hospital of Traditional Chinese Medicine Unknown No outcome recorded
Phase 2/3 NCT00152633 Comparator Sep 2005 → Jan 2006 hypertensive disorder University of Erlangen-Nürnberg Medical School Withdrawn No outcome recorded
Phase 333 trials
Phase 3 NCT05619653 Comparator Dec 2022 → Aug 2025 overdue inflammation of heart layer, long COVID-19 Valentina Puentmann Active not recruiting No outcome recorded
Phase 3 NCT04074551 Comparator Jul 2019 → Mar 2020 hyperlipidemia, hypertensive disorder Hanmi Pharmaceutical Company Limited Completed No outcome recorded
Phase 3 NCT03082014 Comparator Feb 2018 → Jul 2022 cerebrovascular disorder Ludwig-Maximilians - University of Munich Terminated No outcome recorded
Phase 3 NCT02521233 Comparator Nov 2016 → May 2017 essential hypertension EMS Withdrawn No outcome recorded
Phase 3 NCT02521246 Comparator Nov 2016 → May 2017 essential hypertension EMS Withdrawn No outcome recorded
Phase 449 trials
Phase 4 NCT07547878 Comparator Apr 2026 → Mar 2029 expected chronic kidney disease, type 2 diabetes mellitus Baylor Research Institute Not yet recruiting No outcome recorded
Phase 4 NCT07513883 Background Mar 2026 → Sep 2028 expected heart failure Ziekenhuis Oost-Limburg Recruiting No outcome recorded
Phase 4 NCT05843162 Comparator Jun → Dec 2023 essential hypertension, metabolic syndrome X Chong Kun Dang Pharmaceutical Unknown No outcome recorded
Phase 4 NCT04662723 Background May 2023 → Jun 2026 overdue IgA glomerulonephritis Schena Foundation Recruiting No outcome recorded
Phase 4 NCT06431477 Comparator Apr 2023 → Oct 2025 diabetic kidney disease, essential hypertension Chong Kun Dang Pharmaceutical Unknown No outcome recorded
Phase not applicable22 trials
NCT07683585 Comparator Apr → Jul 2026 overdue coronary artery disorder, hypertensive disorder National Medical Research Center for Therapy and Preventive Medicine Recruiting No outcome recorded
NCT07568574 Background Mar 2026 → May 2028 expected Enhanced Emirates Limited Enrolling by invitation No outcome recorded
NCT07449000 Comparator Feb 2026 → Feb 2027 expected corneal disorder Autonomous University of Nuevo León Recruiting No outcome recorded
NCT06539806 Comparator Jul 2024 → Aug 2026 overdue malignant pancreatic neoplasm Tanta University Recruiting No outcome recorded
NCT06344247 Background Sep 2023 → Sep 2025 chronic kidney disease, obesity disorder RenJi Hospital Unknown No outcome recorded

Press releases naming this drug 4 releases

DateIssuerRelease
2010-04-07 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Final Approval of Generic Hyzaar® and Cozaar® tevapharm.com
2010-03-02 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Favorable Court Ruling in Generic Hyzaar® and Cozaar® Litigation tevapharm.com
2006-06-14 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Tentative Approval of Losartan Potassium & Hydrochlorothiazide Tablets tevapharm.com
2006-05-28 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Tentative Approval for Generic Cozaar® Tablets tevapharm.com

Evidence & citations 44 cited values

Every value below carries the sentence it was read from. 393 sources stand behind the page.

FieldValueCited text
Known as Losartán “The pharmacological treatment intended to enhance reverse remodeling includes 4 drugs initiated immediately after weaning of inotropic support once achieving adequate end-organ...” NCT01774656
371

“The study intervention will be a heart failure with reduced ejection fraction (HFrEF) polypill consisting of bisoprolol (beta-blocker), losartan (ARB), eplerenone (MRA), and...” NCT07569640

“HFrEF polypill strength 1: bisoprolol 2.5 mg + losartan 25 mg + eplerenone 25 mg + dapagliflozin 10 mg; HFrEF polypill strength 2: bisoprolol 5 mg + losartan 50 mg + eplerenone...” NCT06831864

“Two equally loaded capsules containing: Melatonin (2.0 mg) Nicotine (1.0 mg) Bupropion (37.5 mg) Repaglinide (0.25 mg) Losartan (12.5 mg) Omeprazole (10 mg) Chlorzoxazone...” NCT03563287

“Oral losartan given in the dose of 50 mg one hour before ERCP was studied in the prevention of post ERCP pancreatitis in 50 patients indicated for ERCP in comparison with...” NCT04049734

“One of ARBs(Valsartan, Olmesartan, Candesartan, Telmisartan, Fimasartan, Losartan and Irbesartan) and one of statins(Rosuvastatin, Atorvastatin, Pitavastatin, Simvastatin,...” NCT04061824

“Midazolam, repaglinide, and losartan (CYP probe substrates) and, for female participants, estradiol/norethisterone acetate (hormonal probe substrate), administered orally (PO)...” NCT07704658

“Pharmacokinetics of a Fixed-Dose Combination Product of Amlodipine, Losartan, Ezetimibe, and Rosuvastatin and Its Comparison with Co-administration of Four Individual...” PMID 38775910 May 2024

Losartán dosage: 12.5 mg /day for patients \< 50 Kg or 25 mg/day for patients \> 50 Kg (14 days). 50 mg/day from day 15 to the end of the study. Half of dose (25 mg/day) for...” NCT01145612

“The objective of this study was to evaluate the efficacy and tolerability of a triple combination of amlodipine/losartan/rosuvastatin in patients with hypertension and...” PMID 29150250 Nov 2017

“Two randomized studies were designed to assess the safety, tolerability and efficacy of losartan 100 mg (L100) plus hydrochlorothiazide 12.5 mg (H12.5) in a single fixed-dose...” PMID 24990091 Jul 2014

“probe drugs for simultaneous phenotyping of CYP1A2 (caffeine), CYP2B6 (efavirenz), CYP2C9 (losartan), 2C19 (omeprazole), CYP2D6 (metoprolol), and CYP3A4 (midazolam)” PMID 26123704 Jan 2016

“Blood Pressure Control: Antihypertensive drugs such as amlodipine tablets (5 mg qd), nifedipine tablets (30 mg qd), or losartan tablets (100 mg qd) can be selected.” NCT06796660

“Angiotensin II receptor antagonists ,these medicines have names that end in "sartan".For examples:losartan,candesartan,irbesartan,olmesartan,telmisartan,valsartan” NCT01377285

“ZYN002 (transdermal), midazolam (oral), omeprazole (oral), losartan (oral), dextromethorphan (oral), caffeine (oral), repaglinide (oral), bupropion (oral)” NCT06930872

“Japanese patients with uncontrolled essential hypertension received single-blind losartan 50 mg/hydrochlorothiazide 12.5 mg (L50/H12.5) for 8 weeks.” PMID 25271811 Oct 2014

“A Randomized, Double-Blind, Two Arm, Parallel Group Health Assessment Study of Losartan or Atenolol in Patients With Mild to Moderate Hypertension” NCT00541684

“RAAS (Lisinopril, Enalapril, Perindopril, Losartan, and Valsartan taken each day at maximum tolerated dose that will different for each subject)” NCT03502031

“Oral drug cocktail consisting of caffeine (100 mg), dextromethorphan (30 mg), losartan (25 mg), midazolam syrup (2 mg), and omeprazole (20 mg).” NCT06693960

“If the patient is intolerant to either of these, an angiotensin receptor blocker (ARB)(Candesartan, Losartan, Valsartan) will be introduced.” NCT05637853

“They will receive Losartan (Cozaar 50 mg) Dosage: One tablet 2 hours before ESWL Then one tablet every day after ESWL for one week” NCT01675362

“Single oral administration of caffeine (100mg), omeprazole (20mg), losartan (25mg), dextromethorphan (30mg), and midazolam (1mg)” NCT04201197

“modified "karolinska cocktail" (dextromethorphan, caffeine, losartan, omeprazole and paracetamol) before bariatric surgery” NCT01086722

“INV-144 is a combination drug product consisting of losartan potassium (50mg) and alpha lipoic acid (600 mg)” NCT01398423

“A combination of finerenone 10 mg, empagliflozin 12.5 mg, and losartan 50 mg or 100 mg within a polycapsule.” NCT06143566

“The study recommends physicians to select evidence-based ARBs such as candesartan or valsartan or losartan.” NCT04591210

“Cozzar tablet: Losartan potassium 50mg, 100mg/cap, orally, 1 capsule once a day during 16 weeks” NCT01766505

“Candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, valsartan” NCT04330300

“Losartan is an ANG II receptor antagonist which attenuates ET-1 production.” NCT03371823

“prescription of antihypertensives (amlodipine and/or losartan OR enalapril)” NCT05479097

“ARB (second line alternative to ACEi): valsartan, losartan or candesartan” NCT07513883

“includes midazolam, caffeine, losartan, omeprazole, and dextromethorphan” NCT03505853

“40-80 mg benazepril plus 25-100 mg losartan orally once or twice daily” NCT00907374

“Group A patients will be prescribed ARBs (losartan 50 mg/day)” NCT07586371

“eprosartan, irbesartan, losartan, olmesartan, telmisartan” NCT00684489

“MICARDIS® (Telmisartan) and COZAAR® / LORZAAR® (Losartan)” NCT02200653

“spironolactone 25 mg once daily added to losartan” NCT01667614

“equal to Losartan 50mg or Captopril 25mg bid” NCT05064904

“amlodipine, Losartan, Chlorthalidone FDC” NCT02916602

“losartan 50 mg daily in adult patients” NCT00280215

“use losartan to control blood pressure” NCT01230216

“PO Losartan 25mg every 24 hours.” NCT04428268

“Amlodipine 5mg /Losartan 100mg” NCT01828359

“Losartan 50 mg : 1cp de 50mg” NCT01443039

“the drug Cozaar (losartan)” NCT00275639

“Losartan 100mg(Cozaar)” NCT04081844

“Losartan 50 mg daily” NCT03357653

“COZAAR® (Losartan)” NCT02200640

“Losartan 150mg/d” NCT02817360

“Losartan 50mg” NCT02056743

“Losartan” NCT04222686

“losartan” NCT04662723

“losartan” NCT01015937

“Losartan” NCT05232370

“Losartan” NCT02735707

NCT01180413

NCT04312009

NCT00223717

NCT00922480

NCT00340678

NCT06636812

NCT07568574

NCT00720577

NCT05097248

NCT04328012

NCT03467217

NCT03276598

NCT03951142

NCT03006952

NCT00813722

NCT04447235

NCT00492128

NCT00795847

NCT01199978

NCT00931710

NCT01292694

NCT05713396

NCT01124162

NCT01210430

NCT00774904

NCT03335904

NCT01124175

NCT07017023

NCT01051219

NCT00732407

NCT01277822

NCT06333522

NCT05871333

NCT00647257

NCT04643691

NCT01087749

NCT01431508

NCT01805453

NCT00467831

NCT02620306

NCT00659451

NCT00090259

NCT05861336

NCT00168857

NCT01041963

NCT00001741

NCT05157464

NCT00981929

NCT01854814

NCT07160361

NCT00723801

NCT01648231

NCT05619653

NCT03604003

NCT01127217

NCT03461003

NCT06933706

NCT00162474

NCT00882440

NCT00561704

NCT00994617

NCT05893108

NCT03435939

NCT02521246

NCT00239096

NCT03897868

NCT01806324

NCT00354991

NCT01934569

NCT00219141

NCT00338091

NCT00739674

NCT04078711

NCT04927299

NCT07099859

NCT04394117

NCT03978884

NCT00670787

NCT01305850

NCT00402194

NCT00732966

NCT06344247

NCT00565396

NCT01964079

NCT06628154

NCT06135493

NCT01276613

NCT01989078

NCT02416102

NCT01845688

NCT05607017

NCT05365893

NCT00419835

NCT03029091

NCT02121041

NCT00602004

NCT04343001

NCT01529749

NCT04349410

NCT04504045

NCT06150560

NCT01479439

NCT01857999

NCT02704494

NCT05843162

NCT04212650

NCT00361023

NCT03396523

NCT01033318

NCT00940667

NCT04335123

NCT05753696

NCT00940680

NCT00151827

NCT02663141

NCT02232776

NCT05212597

NCT00943852

NCT00533858

NCT00716950

NCT03763409

NCT00630708

NCT02049307

NCT01321021

NCT00274638

NCT03692013

NCT03632213

NCT00308347

NCT01176032

NCT05077800

NCT00546052

NCT03082014

NCT01371747

NCT00298714

NCT04715568

NCT03147092

NCT03666351

NCT02560805

NCT04074551

NCT00140985

NCT02235909

NCT03417388

NCT00683124

NCT04815902

NCT03953950

NCT04311177

NCT01150461

NCT01324752

NCT03626259

NCT00369538

NCT05827484

NCT00198562

NCT02263729

NCT00673790

NCT03578042

NCT03563248

NCT00307060

NCT00157963

NCT02172586

NCT02744456

NCT02269176

NCT03295734

NCT05637216

NCT03526042

NCT00388388

NCT01150201

NCT00407862

NCT02521233

NCT00699036

NCT02768948

NCT00234858

NCT00756938

NCT03217825

NCT00496834

NCT06624904

NCT02913664

NCT06211335

NCT01637623

NCT01913470

NCT00381134

NCT00152633

NCT00879879

NCT05370599

NCT01541943

NCT02958631

NCT07300670

NCT03946514

NCT02183701

NCT01224860

NCT00593710

NCT00067990

NCT00289887

NCT01320397

NCT06718062

NCT03206788

NCT00140907

NCT04106856

NCT00092209

NCT00456963

NCT02769130

NCT02231125

NCT05090449

NCT00981747

NCT00971165

NCT04604938

NCT04632589

NCT04340557

NCT00751751

NCT00887250

NCT02446548

NCT03912285

NCT05132712

NCT02248961

NCT00447603

NCT00237588

NCT01447654

NCT01603940

NCT04606563

NCT02278471

NCT00555217

NCT01234922

NCT00651235

NCT00649311

NCT00617877

NCT02166398

NCT01766050

NCT01989793

NCT06539806

NCT02410005

NCT00449111

NCT06491940

NCT00140959

NCT00429364

NCT01145612

NCT02709018

NCT00720226

NCT01384591

NCT00519870

NCT00663377

NCT01852942

NCT07135687

NCT07683585

NCT04606225

NCT00133185

NCT04238702

NCT06364176

NCT00398541

NCT02238457

NCT01570569

NCT00364988

NCT01982695

NCT04954560

NCT05576155

NCT01620788

NCT04604756

NCT07449000

NCT01821729

NCT05402397

NCT00568178

NCT01149486

NCT00675987

NCT02373241

NCT02188121

NCT04539808

NCT00942344

NCT04222686

NCT01011062

NCT00155064

NCT01830517

NCT01808196

NCT02232763

NCT02190318

NCT07265739

NCT01198496

NCT05331144

NCT01149473

NCT00880386

NCT02294539

NCT05012631

NCT01307046

NCT06431477

NCT02010905

NCT01198249

NCT02212769

NCT03878524

NCT00805311

NCT05828940

NCT02696564

NCT07513350

NCT00701428

NCT00814255

NCT00669435

NCT02676466

NCT00362960

NCT01692717

NCT01115426

NCT01271374

NCT02760615

NCT00754429

NCT00185094

NCT03900793

NCT00446563

NCT03434054

NCT04606212

NCT00530595

NCT01858623

NCT00782327

NCT06108063

NCT03864042

NCT00763893

NCT01281787

NCT06329050

NCT04278495

NCT06329076

NCT00143949

NCT00856960

NCT01187862

Known as Allisartan ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as Angizaar ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as Aradois ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as Cozaar “The purpose of this research study is to determine if after one year of treatment telmisartan (MICARDIS, GLIOSARTAN, KINZAL, KINZALMONO, PREDXAL, PRITOR, SAMERTAN, TELMISARTAN)...” NCT00168857
20

“This study was conducted to evaluate and compare the effectiveness of Amodipin® (amlodipine camsylate) with that of Cozaar® (losartan potassium) in hypertensive patients with...” NCT01830517

“in addition to local PRP injection, 50 mg / day of LOSARTAN (Cozaar® 50 mg film-coated tablets) were administrated to the study group orally every morning from day 5 and till...” NCT05827484

“They will receive Losartan (Cozaar 50 mg) Dosage: One tablet 2 hours before ESWL Then one tablet every day after ESWL for one week” NCT01675362

“The commonly prescribed antihypertensive drug losartan (brand name: Cozaar; UK licensed for 20 years)” NCT03763409

COZAAR (losartan potassium) is an angiotensin II receptor (type AT1) antagonist.” NCT03217825

“single-dose losartan potassium (Cozaar; weight-adjusted 25mg or 50mg)” NCT06636812

“MICARDIS® (Telmisartan) and COZAAR® / LORZAAR® (Losartan)” NCT02200653

“losartan 100 mg tablets (test) versus Cozaar® (reference)” NCT01124162

“7-day losartan (Cozaar, 50mg; oral tablet) with 7-day BA” NCT07017023

“oral single-dose losartan potassium (Cozaar; 50mg)” NCT06628154

“the drug Cozaar (losartan)” NCT00275639

Cozaar® (losartan) 50 mg” NCT00496834

“50mg losartan (Cozaar)” NCT05828940

“Losartan 100mg(Cozaar)” NCT04081844

COZAAR® (Losartan)” NCT02200640

NCT01124162

NCT07547878

NCT01390181

NCT00378443

NCT01233635

Known as Cozaar Tab. Cozaar Tab.(Losartan) 50mg(100mg) + Anydipine-S(S-amlodipine) Tab. 2.5mg” NCT05843162
Known as Cozaar: losartan Cozaar: losartanNCT00981747
Known as COZZAR “Losartan (COZZAR®)” NCT05090449
Known as Cozzar tablet Cozzar tablet: Losartan potassium 50mg, 100mg/cap, orally, 1 capsule once a day during 16 weeks” NCT01766505
Known as DU PONT-753 ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as DUP 753 ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as Dup-89 ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as E-3340 ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as HGP1405 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02387554
1

NCT04252872

Known as L-158086 ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as L50 “50 mg losartan potassium (L50), 12.5 mg hydrochlorothiazide (H12.5), and 5 mg amlodipine besylate (A5)” NCT01302691
Known as LORZAAR “MICARDIS® (Telmisartan) and COZAAR® / LORZAAR® (Losartan)” NCT02200653
Known as LOS “olmesartan medoxomil (OM) versus losartan potassium (LOS)” PMID 22763801 Jul 2012
Known as Losacar ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as Losaprex ChEMBL registry synonym — accepted as the source's own label CHEMBL191
Known as losartan (Cozaar) losartan (Cozaar)NCT02238457
Known as losartan (Cozaar, Merck Sharp & Dohme, Wilmington, DE, USA) losartan (Cozaar, Merck Sharp & Dohme, Wilmington, DE, USA)NCT00519870
Known as Losartan (generic name) Losartan (generic name)NCT01124175
Known as Losartan also known as Cozaar Losartan also known as CozaarNCT01051219
Known as Losartan monopotassium salt ChEMBL registry synonym — accepted as the source's own label CHEMBL191