Pharmacokinetic Interaction Between HGP0904, HGP0608 and HGP1405

Phase 1 Completed 33 enrolled Hanmi Pharmaceutical Company Limited Seoul National University Bundang Hospital · collab

RandomizedCrossoverOpen-labelBasic science

Summary

The purpose of this study is to investigate the pharmacokinetic interaction and safety between HGP0904, HGP0608 and HGP1405 when administered alone and in combination in healthy male volunteers

Timeline

Start: 2014-08
Primary completion: 2014-10
Completion: 2014-10

Publications

Moon SJ, Hong SH, Lim Y, Chung JY. Pharmacokinetic Interaction Among Amlodipine, Losartan, and Chlorthalidone after a Single Oral Administration in Healthy Male Subjects. Clin Pharmacol Drug Dev. 2026 Jan;15(1):e70024. doi: 10.1002/cpdd.70024.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Amlodipine	Other / unclassified	5 mg	Oral
Subject	HGP0608	Unknown	100 mg	Oral
Subject	Losartan	Other / unclassified	25 mg	Oral

Pharmacokinetic Interaction Between HGP0904, HGP0608 and HGP1405

Summary

Timeline

Publications

Drugs

Indications