drugset / Trial / NCT03206788
Losartan and Inflammation in Cystic Fibrosis
Phase 2
Terminated
7 enrolled
University of Miami
Children's Hospital Medical Center, Cincinnati · collabCystic Fibrosis Foundation · collabUniversity of Alabama at Birmingham · collabUniversity of Kansas Medical Center · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of the study is to examine if a specific drug called losartan (Cozaar ®), generally used to treat high blood pressure and to protect kidneys from damage in patients suffering from Diabetes Mellitus, will have any effect on the nasal inflammation in patients with cystic fibrosis (CF). The study will be performed at the Pulmonary Division at the University of Miami, Cincinnati Children's Medical Hospital Center, University of Kansas Medical Center and University of Alabama-Birmingham.
Timeline
- Start
- 2017-11-11
- Primary completion
- 2019-10-24
- Completion
- 2019-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Losartan | Other / unclassified | 25 mg | Oral |
| Subject | Losartan | Other / unclassified | 50 mg | Oral |