Efficacy of Losartan + Amlodipine Compared to Amlodipine Alone in the Treatment of Uncontrolled High Blood Pressure (MK-0954F-399)

Summary

This study will determine whether using losartan and amlodipine together will be non-inferior in lowering blood pressure than amlodipine alone.

Timeline

Start

2011-05-30

Primary completion

2013-04-22

Completion

2013-04-22

Outcome

Missed primary endpoint

registry analysis (unspecified test); Losartan/Amlodipine vs Amlodipine; p = 0.1339; Mean Difference (Final Values) -1.3 (95% CI -3.0 to 0.4); t-test, 2 sided NCT01277822 ↗

Drugs

Indications