drugset / Trial / NCT00720226
Efficacy of Losartan in Preventing Progression of COPD
Phase 4
Completed
106 enrolled
Johns Hopkins University
Merck Sharp & Dohme LLC · collabNational Heart, Lung, and Blood Institute (NHLBI) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Evidence in animals shows that losartan can prevent or reverse inflammation and lung damage due to smoking. The goal of this study is to determine whether this drug which is also used to treat hypertension can stabilize or improve lung function in people who have from chronic obstructive pulmonary disease (COPD).
Timeline
- Start
- 2008-07
- Primary completion
- 2014-08
- Completion
- 2016-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Losartan | Other / unclassified | 100 mg | — |