Effects of Losartan on Insulin Sensitivity and Secretion in Type 2 Diabetes and Nephropathy

Summary

Angiotensin type-1 receptor (AT1R) blockers (ARBs) have been recognized recently as regulators of glucose and lipid metabolism in adipocytes and adipose tissue.Moreover telmisartan and irbesartan have been recognized recently as regulators of glucose metabolism. For ARB losartan, the results were controversial. To confirm its effect on glucose metabolism, we designed and performed a prospective, randomized and controlled study in subjects with type 2 diabetes and nephropathy.

Timeline

Start

2006-01

Primary completion

—

Completion

2006-07

Drugs

Indications