drugset / Trial / NCT00496834
LAAS (Losartan Anti-Atherosclerosis Study)(0954-330)(COMPLETED)
RandomizedParallel-groupOpen-labelTreatment
Summary
The primary objective of this study is to evaluate efficacy, arterial stiffness measured by Pulse Wave Velocity (PWV) of Losartan potassium group compared to Carvedilol group after 24 weeks of treatment in patients with the essential hypertension.
Timeline
- Start
- 2008-02-01
- Primary completion
- 2009-09-01
- Completion
- 2009-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Carvedilol | Other / unclassified | 12.5 mg | — |
| Comparator | Carvedilol | Other / unclassified | 25 mg | — |
| Subject | Hydrochlorothiazide | Unknown | 12.5 mg | — |
| Subject | Hydrochlorothiazide | Unknown | 25 mg | — |
| Subject | Losartan | Other / unclassified | 50 mg | — |
| Subject | Losartan | Other / unclassified | 100 mg | — |