Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV

Summary

The purpose of this study is to find out why patients with post-traumatic stress disorder (PTSD) have an increased risk for heart disease and high blood pressure later in life. A second purpose is to find out what causes PTSD patients to have high adrenaline levels during stress. This study will also test if a medicine called losartan improves high adrenaline levels in patients with PTSD and if a certain gene that has to do with high blood pressure might be associated with high adrenaline levels.

Timeline

Start

2015-10

Primary completion

2027-03-30

Completion

2027-03-30

Drugs

Indications