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drugset / Trial / NCT00287300

Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women

NCT00287300 ↗

Completed 141 enrolled University of North Carolina Centers for Disease Control and Prevention · collab

RandomizedParallel-groupOpen-labelPrevention

Summary

The purpose of this study is to compare the efficacy and safety of three treatment regimens for the prevention of malaria during pregnancy.

Timeline

Start: 2003-09
Primary completion: —
Completion: 2005-08

Publications

Kalilani L, Mofolo I, Chaponda M, Rogerson SJ, Alker AP, Kwiek JJ, Meshnick SR. A randomized controlled pilot trial of azithromycin or artesunate added to sulfadoxine-pyrimethamine as treatment for malaria in pregnant women. PLoS One. 2007 Nov 14;2(11):e1166. doi: 10.1371/journal.pone.0001166.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Artesunate	Small molecule	200 mg	—
Subject	Azithromycin	Small molecule	1 g	Oral
Subject	Sulfadoxine-pyrimethamine	Small molecule	3 unknown	—

Indications