drugset / Trial / NCT00288444
Interaction of Docetaxel and Lonafarnib in Patients With Advanced Cancer
Phase 1
Terminated
38 enrolled
Emory University
Aventis Pharmaceuticals · collabSchering-Plough · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
To determine the molecular interaction in tumor samples between docetaxel and lonafarnib.
Timeline
- Start
- 2006-01
- Primary completion
- 2008-05
- Completion
- 2009-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Docetaxel | Small molecule | 30 mg/m2 | Intravenous |
| Comparator | Docetaxel | Small molecule | 36 mg/m2 | Intravenous |
| Comparator | Lonafarnib | Small molecule | 100 mg | Oral |
| Comparator | Lonafarnib | Small molecule | 150 mg | Oral |