drugset / Trial / NCT00290537
Phase II Study of ZD6474 in Advanced NSCLC
RandomizedParallel-groupOpen-labelTreatment
Summary
The goal of this clinical research study is to learn how the drug ZD6474 affects the amount of tumor cell death in the body and the amount of blood that can be supplied to the tumor. The safety of ZD6474 alone and when given with chemotherapy will be studied. In addition, the side effects and response to this treatment will also be studied.
Timeline
- Start
- 2006-01
- Primary completion
- 2008-04
- Completion
- 2008-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carboplatin | Small molecule | 6 unknown | — |
| Subject | Paclitaxel | Small molecule | 200 mg/m2 | Intravenous |
| Subject | Vandetanib | Small molecule | 100 mg | Oral |
| Subject | Vandetanib | Small molecule | 300 mg | Oral |