drugset / Trial / NCT00294502
Antibiotic Lock Solutions in the Prevention of Catheter Related Bacteremia
RandomizedSingle-groupOpen-labelPrevention
Summary
To study the efficacy of an antibacterial/anticoagulant solution instilled into the hemodialysis (HD) catheters after each treatment ("antibiotic lock solution - ALS") to prevent catheter related bacteremia (CRB) and to salvage catheters with established CRB.
Timeline
- Start
- 2003-09
- Primary completion
- —
- Completion
- 2004-05
Publications
- Results Allon M. Dialysis catheter-related bacteremia: treatment and prophylaxis. Am J Kidney Dis. 2004 Nov;44(5):779-91.
- Results Dogra GK, Herson H, Hutchison B, Irish AB, Heath CH, Golledge C, Luxton G, Moody H. Prevention of tunneled hemodialysis catheter-related infections using catheter-restricted filling with gentamicin and citrate: a randomized controlled study. J Am Soc Nephrol. 2002 Aug;13(8):2133-9. doi: 10.1097/01.asn.0000022890.29656.22.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | EDTA | Unknown | — | Other |
| Subject | Gentamicin | Small molecule | — | Other |
| Subject | Minocycline | Small molecule | — | Other |
| Subject | citrate | Unknown | — | Other |