Gentamicin

also known as gentamycin · Gentamicin Sulfate · Garamycin · gentamicin-collagen sponge · Hexamycin · AppliGel-G · Garamycin Sponge · Gentamicin (gentamicin) · +6 more

Small molecule targets CFTR via restoration

Developed for: cutaneous leishmaniasis · urinary tract infection · infectious disease · ulcer of lower limbs · appendicitis · acoustic neuroma · bacterial infectious disease · gonorrhea
+64 more
· infectious disease with sepsis · recessive dystrophic epidermolysis bullosa · abscess · atopic eczema · chronic rhinosinusitis · Duchenne muscular dystrophy · infective endocarditis · junctional epidermolysis bullosa Herlitz type · peritonitis · pneumonia · respiratory tract infectious disorder · sinusitis · skin infection · acute cholangitis · acute intestinal ischemia · alcoholic hepatitis · bacterial infectious disease with sepsis · bacterial meningitis · bacterial pneumonia · Becker muscular dystrophy · benign prostatic hyperplasia · breast disorder · bronchiectasis · bubonic plague · cat-scratch disease · cholangitis · chronic ulcer of skin · colon carcinoma · Crohn's colitis · cystic fibrosis · endophthalmitis · epidermolysis bullosa · esophagitis · ichthyosis · infectious peritonitis · interstitial cystitis · Klebsiella pneumonia · periapical periodontitis · plague · pneumonic plague · prosthesis-related infectious disease · rectal cancer · staphylococcus aureus infection · stomatitis · tracheobronchitis · ulcerative colitis · vestibular disorder · bacterial urinary tract infection · bullous pemphigoid · chorioamnionitis · cystitis · dermatitis · endometritis · HIV infectious disease · hypotrichosis simplex · infectious meningitis · keratitis · Klebsiella infectious disease · Meniere disease · neonatal sepsis · pemphigus vulgaris · periprosthetic joint infection · preterm premature rupture of the membranes · protein-energy malnutrition
Investigated by: U.S. Army Medical Research and Development Command · Innocoll · Assistance Publique - Hôpitaux de Paris · Premier Research · University of Southern California · Hospital General Universitario Elche
+129 more
· Academic Medical Center - University of Amsterdam · University of Florida · Walter Reed Army Institute of Research (WRAIR) · ZonMw: The Netherlands Organisation for Health Research and Development · Assiut University · Duke University · HaEmek Medical Center, Israel · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Lund University · Muhimbili Orthopaedic Institute · National Institute of Allergy and Infectious Diseases (NIAID) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · National Institute of Neurological Disorders and Stroke (NINDS) · Phramongkutklao College of Medicine and Hospital · Silpakorn University · Stony Brook University · University Hospital, Toulouse · University of California, San Francisco · University of Copenhagen · University of Oxford · Aalborg University Hospital · Aarhus University Hospital · Aga Khan University · Al-Rasheed University College · Alice Ho Miu Ling Nethersole Hospital · Amsterdam UMC, location VUmc · Balgrist University Hospital · Baylor College of Medicine · Centers for Disease Control and Prevention · Chulalongkorn University · Combined Military Hospital Quetta · Dallas VA Medical Center · Department for International Development, United Kingdom · Department of Health and Human Services · Esbjerg Hospital - University Hospital of Southern Denmark · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · Flevoziekenhuis · Food and Drug Administration (FDA) · Foreign, Commonwealth and Development Office and Wellcome (216273.Z.19.Z) · Gillette Children's Specialty Healthcare · Henry Ford Health System · Herlev and Gentofte Hospital · Hitit University · Hoth Therapeutics, Inc. · Hôpital Universitaire Joseph Raseta Befelatanana CHU d'Antananarivo · Indiana University · Institut Pasteur · Institut Pasteur de Madagascar · Istanbul Medipol University Hospital · Johns Hopkins Bloomberg School of Public Health · Julie Wei, MD · Kamuzu University of Health Sciences · Kenya Ministry of Health · Kwong Wah Hospital · Lahey Clinic · Lahore General Hospital · London School of Hygiene and Tropical Medicine · MEDSI Clinical Hospital 1, ICU · Mansoura University · Medical Research Council · Medical University of Vienna · Medstar Health Research Institute · Memorial Sloan Kettering Cancer Center · Merck & Co., Inc. · Michael E. DeBakey VA Medical Center · Mikkel Herly · Ministry of Health, Madagascar · Ministry of Health, Uganda · Murdoch Childrens Research Institute · National Institute for Health Research, United Kingdom · National Institutes of Health (NIH) · National University of Malaysia · Nationwide Children's Hospital · Nektar Therapeutics · all 135 on the full record

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	GARAMYCIN	—	1966-03-15	fda.gov ↗

Trials 120 · started per year

today

US approved 1966

19651966196719681969197019711972197319741975197619771978197919801981198219831984198519861987198819891990199119921993199419951996199719981999200020012002200320042005200620072008200920102011201220132014201520162017201820192020202120222023202420252026202720282029

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 03 trials
Phase 0	NCT07643974	Jun 2026 → Sep 2027 expected	multiple sclerosis, spina bifida, spinal cord injury, urinary bladder disorder +1	Medstar Health Research Institute	Not yet recruiting	No outcome recorded
Phase 0	NCT01633762	Apr 2012 → Apr 2013	diabetes mellitus, obesity disorder, osteoporosis	University Hospital, Gentofte, Copenhagen	Completed	No outcome recorded
Phase 0	NCT01878643	Dec 2001 → Dec 2002	primary bacterial infectious disease, respiratory failure, respiratory tract infectious disorder	Stony Brook University	Completed	No outcome recorded
Phase 15 trials
Phase 1	NCT04544943	May 2021 → Sep 2022	atopic eczema	Hoth Therapeutics, Inc.	Completed	No outcome recorded
Phase 1	NCT04967859	Jul 2018 → Nov 2019	—	São Paulo State University	Completed	No outcome recorded
Phase 1	NCT02515448	Oct 2015 → Nov 2016	—	Poitiers University Hospital	Completed	No outcome recorded
Phase 1	NCT00451074	Mar 2007 → Jul 2009	Duchenne muscular dystrophy	Nationwide Children's Hospital	Completed	No outcome recorded
Phase 1	NCT00005574	Feb 2000 → Jan 2001	Becker muscular dystrophy, Duchenne muscular dystrophy	National Institute of Neurological Disorders and Stroke (NINDS)	Completed	No outcome recorded
Phase 1/27 trials
Phase 1/2	NCT04644627	Dec 2020 → Jan 2022	epidermolysis bullosa	Oslo University Hospital	Completed	No outcome recorded
Phase 1/2	NCT04140786	Oct 2019 → Nov 2023	junctional epidermolysis bullosa Herlitz type	University of Southern California	Unknown	No outcome recorded
Phase 1/2	NCT03392909	Jul 2018 → Dec 2023	recessive dystrophic epidermolysis bullosa	University of Southern California	Unknown	No outcome recorded
Phase 1/2	NCT03526159	Jun 2018 → Jul 2020 overdue	junctional epidermolysis bullosa Herlitz type	University of Southern California	Recruiting	No outcome recorded
Phase 1/2	NCT03012191	Feb 2017 → May 2018	recessive dystrophic epidermolysis bullosa	University of Southern California	Completed	No outcome recorded
Phase 1/2	NCT02698735	Feb 2016 → Mar 2017	recessive dystrophic epidermolysis bullosa	University of Southern California	Completed	No outcome recorded
Phase 1/2	NCT02036528	Jan → Dec 2014	ulcer of lower limbs	Royer Biomedical, Inc.	Terminated	No outcome recorded
Phase 224 trials
Phase 2	NCT06007352	Oct 2024 → Oct 2025	infectious disease with sepsis, urinary tract infection	Yale University	Withdrawn	No outcome recorded
Phase 2	NCT06362447	Sep 2024 → Apr 2026 overdue	ichthyosis	University Hospital, Toulouse	Not yet recruiting	No outcome recorded
Phase 2	NCT07407491	Jul 2024 → Jul 2026 overdue	acute cholangitis, biliary tract cancer, choledocholithiasis	National University of Malaysia	Recruiting	No outcome recorded
Phase 2	NCT05303909	May 2022 → May 2024	—	Singapore General Hospital	Terminated	No outcome recorded
Phase 2	NCT05287425	Aug 2019 → Aug 2023	—	Medical University of Vienna	Completed	No outcome recorded
Phase 2	NCT04039750	Jul 2019 → Dec 2026 expected	appendicitis	Prisma Health-Upstate	Active not recruiting	No outcome recorded
Phase 2	NCT03476941	Apr 2019 → May 2021 overdue	abscess	University of Iowa	Recruiting	No outcome recorded
Phase 2	NCT03931408	Feb 2019 → Jul 2020	spinal cord injury	University of Louisville	Completed	No outcome recorded
Phase 2	NCT03778008	Dec 2018 → Dec 2019	stomatitis	Second Affiliated Hospital of Nanchang University	Unknown	No outcome recorded
Phase 2	NCT02784821	Jan 2017 → Sep 2019	bacterial infectious disease, bronchopulmonary dysplasia, intestinal perforation, intracerebral hemorrhage +3	University of Florida	Completed	No outcome recorded
Phase 2	NCT02577393	Apr 2015 → Jun 2022	esophagitis, lung neoplasm	Shandong Cancer Hospital and Institute	Unknown	No outcome recorded
Phase 2	NCT01988909	Sep 2013 → Dec 2015	cutaneous leishmaniasis	Assistance Publique - Hôpitaux de Paris	Completed	No outcome recorded
Phase 2	NCT01140191	Sep → Dec 2013	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Terminated	No outcome recorded
Phase 2	NCT01494350	Dec 2011 → Jun 2012	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Terminated	No outcome recorded
Phase 2	NCT01570192	Sep 2010 → Apr 2015	bacterial pneumonia	University of Florida	Terminated	No outcome recorded
Phase 2	NCT00659646	Apr 2008 → May 2009	ulcer of lower limbs	Innocoll	Completed	No outcome recorded
Phase 2	NCT00658957	Apr 2008 → Oct 2009	ulcer of lower limbs	Innocoll	Terminated	No outcome recorded
Phase 2	NCT00593567	Dec 2007 → May 2009	ulcer of lower limbs	Innocoll	Completed	No outcome recorded
Phase 2	NCT00657917	Dec 2006 → Jun 2007	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Terminated	No outcome recorded
Phase 2	NCT00317070	Apr 2006 → Feb 2009	interstitial cystitis	Nova Scotia Health Authority	Terminated	No outcome recorded
Phase 2	NCT01536795	Oct 2005 → Feb 2007	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Completed	No outcome recorded
Phase 2	NCT00396578	Aug 2003 → Sep 2004	respiratory tract infectious disorder, tracheobronchitis	Stony Brook University	Completed	No outcome recorded
Phase 2	NCT00703924	Mar 2003 → Nov 2004	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Completed	No outcome recorded
Phase 2	NCT00376428	Jan 2003 → Jun 2005	cystic fibrosis	Assistance Publique - Hôpitaux de Paris	Terminated	No outcome recorded

Phase 2/34 trials
Phase 2/3	NCT04238923	May 2020 → May 2021	peripheral vascular disease	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's	Unknown	No outcome recorded
Phase 2/3	NCT03632109	Sep 2018 → Mar 2019	gonorrhea	University of Washington	Terminated	No outcome recorded
Phase 2/3	NCT03503513	Aug 2018 → Sep 2023	spinal cord injury, urinary tract infection	University of Michigan	Completed	No outcome recorded
Phase 2/3	NCT00128466	Aug 2004 → Feb 2007	plague	Centers for Disease Control and Prevention	Completed	No outcome recorded
Phase 324 trials
Phase 3	NCT06841003	Feb 2025 → Mar 2027 expected	abscess, appendicitis	Spaarne Gasthuis	Not yet recruiting	No outcome recorded
Phase 3	NCT06387147	Jan 2025 → Nov 2027 expected	acute intestinal ischemia	Assistance Publique - Hôpitaux de Paris	Recruiting	No outcome recorded
Phase 3	NCT05766670	Apr 2024 → Jan 2027 expected	osteomyelitis	Wake Forest University Health Sciences	Recruiting	No outcome recorded
Phase 3	NCT05502380	Sep 2022 → Dec 2024 overdue	bacterial infectious disease	Balgrist University Hospital	Recruiting	No outcome recorded
Phase 3	NCT04731025	Jan 2021 → Feb 2027 expected	breast disorder, poisoning, prosthesis-related infectious disease	Mikkel Herly	Recruiting	No outcome recorded
Phase 3	NCT04110340	Feb 2020 → Apr 2024	bubonic plague, pneumonic plague	University of Oxford	Completed	No outcome recorded
Phase 3	NCT04041791	Aug 2019 → Apr 2024	pneumonia	University of Oxford	Completed	No outcome recorded
Phase 3	NCT03491540	Sep 2018 → Oct 2023	rectal cancer	Assistance Publique - Hôpitaux de Paris	Completed	No outcome recorded
Phase 3	NCT03475680	Aug 2018 → Aug 2021	colon carcinoma	Assistance Publique - Hôpitaux de Paris	Terminated	No outcome recorded
Phase 3	NCT03303677	Apr → Nov 2018	chronic rhinosinusitis	University of Florida	Withdrawn	No outcome recorded
Phase 3	NCT03294395	Sep 2017 → Jun 2020	gonorrhea	Public Health Service of Amsterdam	Completed	No outcome recorded
Phase 3	NCT03132116	May 2017 → Aug 2025	cat-scratch disease	University Hospital, Toulouse	Completed	No outcome recorded
Phase 3	NCT03081962	Feb → Aug 2017	—	Hospital General Universitario Elche	Unknown	No outcome recorded
Phase 3	NCT02447172	Jun 2015 → Sep 2016	infectious disease, ulcer of lower limbs	Innocoll	Completed	No outcome recorded
Phase 3	NCT02427802	May 2015 → Oct 2016	chronic ulcer of skin, skin infection	Innocoll	Completed	No outcome recorded
Phase 3	NCT02479971	Jan 2014 → Jun 2015	—	Hospital General Universitario Elche	Completed	No outcome recorded
Phase 3	NCT01790659	May 2013 → Jan 2016	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Completed	No outcome recorded
Phase 3	NCT01667874	Jan 2013 → Sep 2016	infectious disease	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's	Terminated	No outcome recorded
Phase 3	NCT02314806	Jan 2013 → Dec 2014	breast cancer	Hospital General Universitario Elche	Completed	No outcome recorded
Phase 3	NCT01700504	May 2011 → Sep 2012	—	Hospital General Universitario Elche	Completed	No outcome recorded
Phase 3	NCT00606580	Jan 2008 → Jul 2011	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Completed	No outcome recorded
Phase 3	NCT00600925	Jan 2008 → Mar 2009	—	Innocoll	Completed	No outcome recorded
Phase 3	NCT00600483	Dec 2007 → Sep 2010	—	Innocoll	Completed	No outcome recorded
Phase 3	NCT00189384	Nov 2003 → Dec 2005	bacterial infectious disease with sepsis	Aga Khan University	Unknown	No outcome recorded

Phase 432 trials
Phase 4	NCT07563504	Jul 2026 → Jan 2027 expected	—	Sarawak General Hospital	Not yet recruiting	No outcome recorded
Phase 4	NCT07220967	Oct 2025 → Oct 2027 expected	breast cancer	Memorial Sloan Kettering Cancer Center	Recruiting	No outcome recorded
Phase 4	NCT06332781	Apr → Sep 2025	urinary tract infection	Women and Infants Hospital of Rhode Island	Completed	No outcome recorded
Phase 4	NCT06209047	Oct 2023 → May 2026 overdue	bronchiectasis	Assiut University	Recruiting	No outcome recorded
Phase 4	NCT06332040	Oct 2023 → Oct 2026 expected	urinary tract infection	St. Joseph's Hospital and Medical Center, Phoenix	Recruiting	No outcome recorded
Phase 4	NCT05862402	May 2023 → May 2024	Klebsiella pneumonia	Phramongkutklao College of Medicine and Hospital	Unknown	No outcome recorded
Phase 4	NCT05157126	Sep 2022 → Apr 2028 expected	—	University of California, San Francisco	Recruiting	No outcome recorded
Phase 4	NCT04876131	May 2022 → May 2028 expected	urinary tract infection	Murdoch Childrens Research Institute	Recruiting	No outcome recorded
Phase 4	NCT04753723	Feb → Nov 2021	skin infection	The Metis Foundation	Completed	No outcome recorded
Phase 4	NCT03483363	Oct 2018 → Jan 2022	—	The University of Texas Health Science Center, Houston	Terminated	No outcome recorded
Phase 4	NCT02848820	Dec 2016 → Dec 2024	appendicitis	Ramon Gorter	Unknown	No outcome recorded
Phase 4	NCT02415257	Apr 2015 → Sep 2020	acoustic neuroma	Lund University	Withdrawn	No outcome recorded
Phase 4	NCT02423759	Apr 2015 → Jan 2017	benign prostatic hyperplasia	Mansoura University	Completed	No outcome recorded
Phase 4	NCT02379754	Jan 2015 → Jun 2019	acoustic neuroma	Lund University	Withdrawn	No outcome recorded
Phase 4	NCT02898961	Oct 2014 → Dec 2016	infectious disease with sepsis	Nîmes University Hospital	Completed	No outcome recorded
Phase 4	NCT02926846	Mar 2014 → Nov 2017	kidney failure, peritonitis	Alice Ho Miu Ling Nethersole Hospital	Completed	No outcome recorded
Phase 4	NCT01982864	Oct 2013 → Jan 2016	end stage renal failure	University Hospital, Limoges	Terminated	No outcome recorded
Phase 4	NCT01951768	Sep 2013 → Jun 2016	ulcer of lower limbs	University Hospital, Geneva	Completed	No outcome recorded
Phase 4	NCT01884467	May 2013 → Dec 2015	urinary tract infection	Gillette Children's Specialty Healthcare	Unknown	No outcome recorded
Phase 4	NCT01585129	Sep 2010 → Jul 2014	—	Washington University School of Medicine	Terminated	No outcome recorded
Phase 4	NCT00926796	Jun 2010 → Dec 2012	gonorrhea	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 4	NCT01247909	Apr 2010 → Feb 2015	bacterial meningitis	Kamuzu University of Health Sciences	Completed	No outcome recorded
Phase 4	NCT00671528	Jul 2009 → May 2010	atopic eczema	Organon and Co	Terminated	No outcome recorded
Phase 4	NCT00638157	Feb 2009 → Nov 2011	infective endocarditis	Merck & Co., Inc.	Terminated	No outcome recorded
Phase 4	NCT00751374	Sep 2008 → Oct 2014	mycobacterial infectious disease	Kwong Wah Hospital	Unknown	No outcome recorded
Phase 4	NCT01678365	Jul 2008 → Oct 2009	appendicitis	HaEmek Medical Center, Israel	Completed	No outcome recorded
Phase 4	NCT00480376	Jun 2007 → Mar 2008	infectious disease	HaEmek Medical Center, Israel	Unknown	No outcome recorded
Phase 4	NCT00671541	Mar 2006 → Feb 2012	chronic rhinosinusitis	Lahey Clinic	Withdrawn	No outcome recorded
Phase 4	NCT00304811	Jan 2006 → Jan 2007	staphylococcus aureus infection	Michael E. DeBakey VA Medical Center	Completed	No outcome recorded
Phase 4	NCT00294502	Sep 2003 → May 2004	end stage renal failure	Henry Ford Health System	Completed	No outcome recorded
Phase 4	NCT00198601	Aug 2003 → Jul 2005	infectious disease	Johns Hopkins Bloomberg School of Public Health	Completed	No outcome recorded
Phase 4	NCT00398658	Mar 2002 → Dec 2004	endophthalmitis	Shahid Beheshti University of Medical Sciences	Completed	No outcome recorded

Phase not applicable21 trials
—	NCT07655050	Jun 2026 → Feb 2027 expected	nephrolithiasis, urinary tract infection	Hitit University	Recruiting	No outcome recorded
—	NCT07311395	Dec 2025 → Jan 2027 expected	—	Western Galilee Hospital-Nahariya	Recruiting	No outcome recorded
—	NCT07478874	Jul → Dec 2025	—	Lahore General Hospital	Completed	No outcome recorded
—	NCT07704398	Oct 2023 → Apr 2026	periapical periodontitis	Istanbul Medipol University Hospital	Completed	No outcome recorded
—	NCT05750966	Jul 2023 → Apr 2026	cholangitis	Academic Medical Center - University of Amsterdam	Completed	No outcome recorded
—	NCT05251584	Dec 2021 → Mar 2023	infectious peritonitis	Phramongkutklao College of Medicine and Hospital	Unknown	No outcome recorded
—	NCT04839653	May 2021 → Apr 2022	acute respiratory distress syndrome, bacterial infectious disease, infectious disease with sepsis, pneumonia	MEDSI Clinical Hospital 1, ICU	Unknown	No outcome recorded
—	NCT05355610	Apr 2021 → Apr 2022	vestibular disorder	Combined Military Hospital Quetta	Unknown	No outcome recorded
—	NCT06454643	Jan 2020 → Jan 2021	—	Al-Rasheed University College	Completed	No outcome recorded
—	NCT03559400	Nov 2019 → Sep 2021	—	University of California, San Francisco	Completed	No outcome recorded
—	NCT03688659	Jan 2019 → Jan 2021	infective endocarditis	Assiut University	Unknown	No outcome recorded
—	NCT03157388	Jun 2017 → Jun 2018	alcoholic hepatitis	University of Aarhus	Completed	No outcome recorded
—	NCT02033408	Jan 2014 → Dec 2018	Crohn's colitis, ulcerative colitis	Shaare Zedek Medical Center	Completed	No outcome recorded
—	NCT02963896	Jan 2014 → Dec 2015	acoustic neuroma	University Hospital, Motol	Completed	No outcome recorded
—	NCT01785641	Dec 2012 → Dec 2013	peritonitis	Chulalongkorn University	Completed	No outcome recorded
—	NCT01356641	Sep 2012 → Jan 2017	appendicitis	Ramon R. Gorter	Completed	No outcome recorded
—	NCT01153191	Aug 2010 → Sep 2012	infectious disease	Dallas VA Medical Center	Unknown	No outcome recorded
—	NCT00669799	Mar 2008 → Jan 2010	sinusitis	University of South Florida	Withdrawn	No outcome recorded
—	NCT00596167	Sep 2007 → Apr 2009	end stage renal failure, infectious disease	Indiana University	Completed	No outcome recorded
—	NCT00490230	Apr → Jun 2007	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Completed	No outcome recorded
—	NCT00465530	Mar 2007 → Mar 2010	sinusitis	Julie Wei, MD	Completed	No outcome recorded

Also used as a comparator or background therapy in 66 trials

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 01 trial
Phase 0	NCT02099240 Comparator	Mar 2014 → Nov 2018	osteomyelitis	University of Louisville	Terminated	No outcome recorded
Phase 11 trial
Phase 1	NCT03213249 Comparator	Jul 2017 → Sep 2018	breast disorder	Washington University School of Medicine	Completed	No outcome recorded
Phase 28 trials
Phase 2	NCT06428448 Background	Feb 2026 → Aug 2027 expected	periprosthetic joint infection	OsteoRemedies, LLC	Recruiting	No outcome recorded
Phase 2	NCT05702762 Comparator	Oct 2022 → Jun 2023	cystitis	Mercy Health Ohio	Unknown	No outcome recorded
Phase 2	NCT04246996 Comparator	Jan 2020 → Dec 2021	female stress incontinence, pelvic organ prolapse, urinary tract infection	Kaiser Permanente	Completed	No outcome recorded
Phase 2	NCT03492866 Comparator	Apr 2018 → Feb 2019	hypotrichosis simplex	Tel-Aviv Sourasky Medical Center	Unknown	No outcome recorded
Phase 2	NCT03453177 Background	Mar 2018 → Mar 2019	neonatal sepsis	Drugs for Neglected Diseases	Completed	No outcome recorded
Phase 2	NCT02735317 Comparator	Apr 2016 → Jun 2017	nasopharyngeal neoplasm, stomatitis	Yun-fei Xia	Unknown	No outcome recorded
Phase 2	NCT01083576 Comparator	Mar 2010 → Jun 2011	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Completed	No outcome recorded
Phase 2	NCT01032382 Comparator	Jan 2010 → Mar 2011	cutaneous leishmaniasis	U.S. Army Medical Research and Development Command	Completed	No outcome recorded

Phase 2/38 trials
Phase 2/3	NCT05051163 Comparator	Jun 2021 → Jun 2024	HIV infectious disease, protein-energy malnutrition	Makerere University	Unknown	No outcome recorded
Phase 2/3	NCT03622450 Comparator	Jan 2016 → Jan 2018	—	Nourhan Hassan Osama Thuraya Mohamed	Completed	No outcome recorded
Phase 2/3	NCT01931592 Comparator	Jan 2014 → Oct 2016	cancer	Maria J.G.T. Vehreschild	Terminated	No outcome recorded
Phase 2/3	NCT01994993 Comparator	Dec 2013 → Jan 2017	—	Michael Cohen-Wolkowiez	Completed	No outcome recorded
Phase 2/3	NCT00879190 Comparator	May 2009 → Jun 2012	chorioamnionitis	Stanford University	Completed	No outcome recorded
Phase 2/3	NCT00802529 Comparator	Apr 2009 → May 2015	Meniere disease	Imperial College London	Completed	No outcome recorded
Phase 2/3	NCT01633294 Comparator	Oct 2008 → Jan 2011	chorioamnionitis, endometritis, infectious meningitis, neonatal sepsis	Hospital de Santa Maria, Portugal	Completed	No outcome recorded
Phase 2/3	NCT01244256 Background	Apr → Aug 2007	folliculitis	Azidus Brasil	Suspended	No outcome recorded

Phase 313 trials
Phase 3	NCT07107477 Comparator	May 2025 → Sep 2027 expected	preterm premature rupture of the membranes	The Central and Eastern European Gynecologic Oncology Group	Recruiting	No outcome recorded
Phase 3	NCT05977400 Comparator	Apr 2024 → Mar 2029 expected	neurodevelopmental disorder	Sharp HealthCare	Not yet recruiting	No outcome recorded
Phase 3	NCT06489431 Comparator	Dec 2023 → May 2026 overdue	erectile dysfunction, prosthesis-related infectious disease	Rush University Medical Center	Active not recruiting	No outcome recorded
Phase 3	NCT05658874 Background	Dec 2022 → Dec 2024	interstitial cystitis, levator syndrome	Jocelyn Fitzgerald	Terminated	No outcome recorded
Phase 3	NCT05594472 Comparator	Nov 2022 → Apr 2023	bullous pemphigoid, pemphigus vulgaris	Cairo University	Unknown	No outcome recorded
Phase 3	NCT05429671 Comparator	Jun 2022 → Nov 2023	—	Rothman Institute Orthopaedics	Completed	No outcome recorded
Phase 3	NCT05164081 Background	Jan 2022 → Jan 2026 overdue	periprosthetic joint infection	Umeå University	Active not recruiting	No outcome recorded
Phase 3	NCT03174236 Comparator	Sep 2017 → Jan 2020	poisoning, protein-energy malnutrition	University of Oxford	Unknown	No outcome recorded
Phase 3	NCT02717871 Comparator	Mar 2016 → Oct 2020	keratitis	University Hospital, Geneva	Completed	No outcome recorded
Phase 3	NCT02579161 Comparator	Sep 2014 → Mar 2018	urolithiasis	Northwell Health	Completed	No outcome recorded
Phase 3	NCT01551394 Comparator	Sep 2012 → Dec 2014	infectious disease with sepsis	PENTA Foundation	Completed	No outcome recorded
Phase 3	NCT01429701 Comparator	May → Jun 2012	dermatitis	EMS	Completed	No outcome recorded
Phase 3	NCT01027429 Comparator	Dec 2009 → Dec 2013	neonatal sepsis	Aga Khan University	Completed	No outcome recorded

Phase 417 trials
Phase 4	NCT06712641 Comparator	Apr 2026 → Jun 2028 expected	infectious disease with sepsis	University Hospital, Akershus	Recruiting	No outcome recorded
Phase 4	NCT07236944 Comparator	Dec 2025 → Mar 2029 expected	bacterial urinary tract infection	Uppsala University	Recruiting	No outcome recorded
Phase 4	NCT06814223 Comparator	Oct 2024 → Dec 2027 expected	prosthesis-related infectious disease	Western Galilee Hospital-Nahariya	Recruiting	No outcome recorded
Phase 4	NCT05971537 Comparator	Jun 2023 → Oct 2026 expected	infectious peritonitis	Alice Ho Miu Ling Nethersole Hospital	Recruiting	No outcome recorded
Phase 4	NCT05421741 Comparator	May 2023 → Dec 2026 expected	osteomyelitis	Wake Forest University Health Sciences	Recruiting	No outcome recorded
Phase 4	NCT04285320 Comparator	Mar 2021 → Apr 2023	urinary tract infection	Atlantic Health System	Unknown	No outcome recorded
Phase 4	NCT03997266 Comparator	Aug 2020 → Jan 2026	neonatal sepsis, perinatal necrotizing enterocolitis	Michael Morowitz	Completed	No outcome recorded
Phase 4	NCT03560232 Comparator	Jul 2018 → Feb 2020	—	Mercy Health Ohio	Terminated	No outcome recorded
Phase 4	NCT03299387 Comparator	Jun 2017 → Jul 2018	urinary tract infection	Mayo Clinic	Withdrawn	No outcome recorded
Phase 4	NCT02582099 Comparator	Jan 2017 → Jun 2019	sinusitis	Mahidol University	Unknown	No outcome recorded
Phase 4	NCT03007225 Comparator	Jul 2015 → Aug 2016	hepatocellular carcinoma	Ain Shams University	Completed	No outcome recorded
Phase 4	NCT02384200 Background	Mar 2015 → Feb 2017	nephrolithiasis, urinary tract infection	University of California, San Diego	Completed	No outcome recorded
Phase 4	NCT02309346 Background	Dec 2014 → Dec 2023	uterine disorder	Hospital de Clinicas de Porto Alegre	Completed	No outcome recorded
Phase 4	NCT01659866 Comparator	Aug 2012 → Aug 2015	infectious disease	Northwestern University	Completed	No outcome recorded
Phase 4	NCT01273818 Comparator	Jan 2011 → Feb 2013	—	Diskapi Teaching and Research Hospital	Completed	No outcome recorded
Phase 4	NCT00749866 Comparator	May 2007 → Aug 2009	bronchiectasis	University of Edinburgh	Completed	No outcome recorded
Phase 4	NCT00571259 Comparator	Sep 2003 → Jan 2010	bacterial infectious disease	Satellite Healthcare	Completed	No outcome recorded

Phase not applicable18 trials
—	NCT06168708 Comparator	Dec 2023 → Jun 2024	—	Tanta University	Unknown	No outcome recorded
—	NCT05469984 Comparator	Nov 2022 → Sep 2025 overdue	preterm premature rupture of the membranes	Western Galilee Hospital-Nahariya	Recruiting	No outcome recorded
—	NCT05143164 Comparator	Mar 2022 → Jul 2025	—	Singapore General Hospital	Completed	No outcome recorded
—	NCT04438655 Background	May 2019 → Nov 2021	—	University of Turin, Italy	Completed	No outcome recorded
—	NCT02865564 Comparator	Nov 2016 → Mar 2020	digestive system disorder	University Medical Centre Ljubljana	Completed	No outcome recorded
—	NCT02829060 Comparator	Jan 2016 → Jan 2025	infectious disease with sepsis, nephrolithiasis, urinary tract infection	University of California, San Diego	Completed	No outcome recorded
—	NCT02395614 Comparator	Dec 2015 → Dec 2020	breast cancer	Vanderbilt University Medical Center	Completed	No outcome recorded
—	NCT02477423 Comparator	Jul 2015 → Jun 2019	perinatal necrotizing enterocolitis, pulmonary immaturity	University of Chicago	Completed	No outcome recorded
—	NCT02288923 Comparator	Mar 2015 → Jul 2018	osteoarthritis, knee	Royal Devon and Exeter NHS Foundation Trust	Completed	No outcome recorded
—	NCT01945450 Comparator	Jan 2014 → Sep 2016	endometritis	Hadassah Medical Organization	Unknown	No outcome recorded
—	NCT01372371 Comparator	Jun 2011 → Jun 2012	infectious disease	Ganga Hospital	Unknown	No outcome recorded
—	NCT01148693 Comparator	Dec 2009 → Dec 2010	cholangitis	Tehran University of Medical Sciences	Completed	No outcome recorded
—	NCT01266499 Comparator	Jul 2009 → Jan 2011	Klebsiella infectious disease	Rambam Health Care Campus	Completed	No outcome recorded
—	NCT00844337 Comparator	Mar 2009 → Sep 2013	infectious disease with sepsis	Johns Hopkins Bloomberg School of Public Health	Completed	No outcome recorded
—	NCT00814905 Comparator	Nov 2008 → Jan 2012	chorioamnionitis	United States Naval Medical Center, Portsmouth	Withdrawn	No outcome recorded
—	NCT00753558 Comparator	Nov 2008 → Jun 2010	—	Soroka University Medical Center	Completed	No outcome recorded
—	NCT00484055 Comparator	Jan 2007 → Aug 2008	drug-resistant tuberculosis, periprosthetic joint infection	Region Örebro County	Completed	No outcome recorded
—	NCT00185991 Comparator	Jun 2004 → Oct 2006	chorioamnionitis	Stanford University	Completed	No outcome recorded

Evidence & citations 19 cited values

Every value below carries the sentence it was read from. 187 sources stand behind the page.

Field	Value	Cited text
Known as	Gentamicin	“Each subject will receive a single dose of 15 mg/kg vancomycin; 2 mg/kg gentamicin and 250 mg levofloxacin administered intravenously over a one-hour infusion period through...” NCT00596167 ↗ 163 “Some commonly used antibiotics for the treatment of PD peritonitis with their suggested concentrations in the antibiotic-lock are quoted as below: Cefazolin 10mg/mL...” NCT05971537 ↗ “Assessment of Cutaneous Leishmaniasis Scar (Caused by Leishmania Major) for Cosmetic Outcome After Treatment With WR279396 (Paromomycin/Gentamicin Cream in Vehicle) Versus a No...” NCT00490230 ↗ “A sample of 802 ELBW preterm infants will undergo web-based stratified block randomization to receive empiric antibiotics (EA; ampicillin and gentamicin) or placebo during...” PMID 35606829 ↗ May 2022 “Antibiotics: Ceftazidime-Avibactam or Combination antibiotics (eg. Meropenem-Colistin, Imipenem-Colistin, Tigecycline-Amikacin, Tigecycline-Gentamicin, Tigecycline-Meropenem or...” NCT05862402 ↗ “Participants were randomly assigned into two groups: a standard root canal treatment group (n = 40) and an adjunctive treatment group receiving submucosal betamethasone and...” NCT07704398 ↗ “WR 279,396 is a topical antibiotic cream containing paromomycin and gentamicin that will be applied to each lesion once a day for 20 days and covered with a sterile gauze and...” NCT01494350 ↗ “OBJECTIVE: To evaluate the efficacy of intraocular gentamicin sulfate and clindamycin in the prevention of acute posttraumatic bacterial endophthalmitis following penetrating...” PMID 17420365 ↗ Apr 2007 “WR 279,396 is a topical antibiotic cream containing 15% paromomycin and 0.5% gentamicin that will be applied to each lesion once a day and covered with a steril” NCT00606580 ↗ “Prevention of tunneled hemodialysis catheter-related infections using catheter-restricted filling with gentamicin and citrate: a randomized controlled study.” PMID 12138146 ↗ Aug 2002 “ampicillin 50mg/kg twice daily and gentamicin \[3mg/kg for babies \<2kg or 5mg/kg for babies \>2kg\] once daily for 7 days, as per Kenyan guidelines).” NCT03453177 ↗ “Patients randomized into this arm will receive one additional dose of gentamicin (1.5 mg/kg) and clindamycin (900mg) in the postpartum setting.” NCT01585129 ↗ “As previous studies have shown promising results for a combination of colistin and gentamicin, the latter was added to the eradication regimen.” NCT01931592 ↗ “The active ingredients of WR279396 are two aminoglycosides - paromomycin sulphate (15%) and gentamicin sulphate (0.5%) - in a base (AQIC).” NCT01536795 ↗ “The antibiotic would be selected from Levaquin, Vancomycin, Gentamicin, Ciprofloxacin, Mupirocin, and Trimethoprim/Sulfamethoxazole” NCT03303677 ↗ “Gentamicin 5 mg/kg IV (\<60 kg 240 mg, 61-80 kg 320 mg, \>80 kg 400 mg) every 24h for 5-7 days according to the clinical state.” NCT07107477 ↗ “Antibiotic prophylaxis is as per the hospital protocol (currently 6mg/kg Teicoplanin IV and 3mg/kg gentamicin pre induction).” NCT02288923 ↗ “broad-spectrum prophylaxis of a combined single-shot of vancomycin 1 g and gentamicin 5 mg/kg parenterally” PMID 38243311 ↗ Jan 2024 “Dudley described the use of topical gentamicin in a case report of a patient with atrophic rhinitis.” NCT00669799 ↗ “The first 10 patients will be treated with the PWD + gentamicin and will serve as a safety subset.” NCT04753723 ↗ “Topical application of WR 279,396 cream (15% paromomycin + 0.5% gentamicin)once daily for 20 days” NCT01140191 ↗ “delivers a consistent dose of fast-release antibiotics called Gentamicin Sulphate (2.0 mg/cm2).” NCT01667874 ↗ “standard chemoprophylaxis plus gentamicin 160mg intramuscular once just before the biopsy” NCT02423759 ↗ “The PMMA of the REMEDY SPECTRUM IM Spacer Nail is laden with gentamicin and vancomycin.” NCT06428448 ↗ “intraperitoneal irrigation with clindamycin (600mg) and gentamicin (240 mg) solution” NCT03081962 ↗ “antibiotic irrigation using gentamicin, clindamycin and suction during the surgery” NCT04039750 ↗ “WR 279,396 is a topical antibiotic cream containing paromomycin and gentamicin” NCT00703924 ↗ “WR 279,396 is a topical cream of paromomycin 15% and gentamicin 0.5%” NCT01790659 ↗ “Intravesical lidocaine, heparin, sodium bicarb, Kenalog, gentamicin” NCT05658874 ↗ “tienam,meropenem,levofloxacin,ciprofloxacin,amikacin,gentamicin” NCT03622450 ↗ “antibiotic powder (Vancomycin 2gm) and 560mg gentamicin liquid.” NCT05421741 ↗ “aminoglycosides; amikacin, gentamicin, tobramycin, 6) other” NCT07236944 ↗ “The first vial of SF will contain 240 mg of gentamicin.” NCT02309346 ↗ “Paromomycin + Gentamicin Topical Cream” NCT01988909 ↗ “Ampicillin or Gentamicin or Cefotaxime” NCT02784821 ↗ “80 mg of gentamicin in 500 mL of NS.” NCT02395614 ↗ “Gentamicin 7 mg/kg once daily” NCT01356641 ↗ “Gentamycin-Gentamicin®” NCT02033408 ↗ “* Gentamicin 80 mg” NCT00317070 ↗ “Gentamicin” NCT02099240 ↗ NCT00593567 ↗ NCT06362447 ↗ NCT06209047 ↗ NCT01148693 ↗ NCT06332781 ↗ NCT01032382 ↗ NCT05157126 ↗ NCT00879190 ↗ NCT02898961 ↗ NCT05251584 ↗ NCT03476941 ↗ NCT03294395 ↗ NCT02717871 ↗ NCT02865564 ↗ NCT00926796 ↗ NCT03526159 ↗ NCT04140786 ↗ NCT03213249 ↗ NCT06454643 ↗ NCT04876131 ↗ NCT03559400 ↗ NCT01027429 ↗ NCT03560232 ↗ NCT00451074 ↗ NCT01659866 ↗ NCT05469984 ↗ NCT00638157 ↗ NCT05702762 ↗ NCT01153191 ↗ NCT01247909 ↗ NCT00005574 ↗ NCT00304811 ↗ NCT04544943 ↗ NCT05287425 ↗ NCT07407491 ↗ NCT00844337 ↗ NCT00600925 ↗ NCT02515448 ↗ NCT00396578 ↗ NCT02579161 ↗ NCT01633762 ↗ NCT07311395 ↗ NCT01273818 ↗ NCT02926846 ↗ NCT01700504 ↗ NCT00376428 ↗ NCT00600483 ↗ NCT02735317 ↗ NCT03174236 ↗ NCT02415257 ↗ NCT00802529 ↗ NCT00749866 ↗ NCT01884467 ↗ NCT05766670 ↗ NCT01083576 ↗ NCT07655050 ↗ NCT05051163 ↗ NCT01878643 ↗ NCT02479971 ↗ NCT01951768 ↗ NCT01994993 ↗ NCT00753558 ↗ NCT06712641 ↗ NCT06489431 ↗ NCT02036528 ↗ NCT01551394 ↗ NCT07563504 ↗ NCT05164081 ↗ NCT07220967 ↗ NCT04967859 ↗ NCT06007352 ↗ NCT01982864 ↗ NCT00657917 ↗ NCT03632109 ↗ NCT06387147 ↗ NCT01633294 ↗ NCT02314806 ↗ NCT00571259 ↗ NCT04238923 ↗ NCT04110340 ↗ NCT05977400 ↗ NCT03392909 ↗ NCT02698735 ↗ NCT00480376 ↗ NCT01678365 ↗ NCT03778008 ↗ NCT03012191 ↗ NCT04731025 ↗ NCT05750966 ↗ NCT06332040 ↗ NCT00185991 ↗ NCT01785641 ↗ NCT06814223 ↗ NCT00198601 ↗ NCT00814905 ↗ NCT05303909 ↗ NCT01244256 ↗ NCT02427802 ↗ NCT05429671 ↗ NCT06841003 ↗ NCT01570192 ↗ NCT03132116 ↗ NCT07643974 ↗ NCT02379754 ↗ NCT06168708 ↗ NCT02829060 ↗ NCT02447172 ↗ NCT05143164 ↗ NCT07478874 ↗ NCT00751374 ↗ NCT00128466 ↗ NCT00484055 ↗ NCT00659646 ↗ NCT01429701 ↗ NCT00189384 ↗ NCT02384200 ↗ NCT02848820 ↗ NCT05355610 ↗ NCT03483363 ↗ NCT02963896 ↗ NCT03299387 ↗ NCT02582099 ↗ NCT00658957 ↗ NCT02477423 ↗
Known as	AppliGel-G	“AppliGel-G is a topically applied hydrogel formulation of gentamicin sulfate (GMS).” NCT02036528 ↗
Known as	Garamycin	“Gentamicin, Garamycin” NCT04140786 ↗ 2 NCT05594472 ↗ NCT01266499 ↗
Known as	Garamycin Sponge	“Garamycin Sponge (Gentamicin-Collagen sponge)” NCT01951768 ↗
Known as	Gentamicin (gentamicin)	“Gentamicin (gentamicin)” NCT00596167 ↗
Known as	Gentamicin Sulfate	“containing Type I bovine collagen and 50 mg of gentamicin sulfate (equivalent to 32.5 mg of gentamicin base)” NCT01951768 ↗ 11 “AppliGel-G is a topically applied hydrogel formulation of gentamicin sulfate (GMS).” NCT02036528 ↗ “Gentamicin Sulfate Inj 20mg/2ml vial for injection” NCT03476941 ↗ “Gentamicin Sulfate, Topical” NCT05143164 ↗ “Drug: Gentamicin Sulfate” NCT03012191 ↗ NCT03492866 ↗ NCT03931408 ↗ NCT00671528 ↗ NCT04246996 ↗ NCT04041791 ↗ NCT03503513 ↗ NCT04644627 ↗
Known as	Gentamicin Sulphate	“delivers a consistent dose of fast-release antibiotics called Gentamicin Sulphate (2.0 mg/cm2).” NCT01667874 ↗
Known as	Gentamicin topical gel	“The purpose of this study is to determine whether AppliGel-G (Gentamicin topical gel) plus oral Ciprofloxacin / Doxycycline are safe and effective in the treatment of mild to...” NCT02036528 ↗
Known as	Gentamicin, Garamycin	“Gentamicin, Garamycin” NCT03012191 ↗
Known as	gentamicin-collagen sponge	“The gentamicin-collagen sponge, a surgically implantable topical antibiotic, is currently approved in 54 countries.” PMID 20716738 ↗ Aug 2010 1 “Garamycin Sponge (Gentamicin-Collagen sponge)” NCT01951768 ↗
Known as	Gentamicins	“Drug: Gentamicins” NCT02379754 ↗
Known as	gentamycin	“The aim of this study is to investigate whether topical aminoglycosides (Gentamycin) may be beneficial for the treatment of HHS patients carrying nonsense mutations by inducing...” NCT03492866 ↗ 16 “mLDG (lidocaine 0.16mg/mL, dexamethasone 0.02mg/mL, and gentamycin 0.16mg/mL) dissolved in 0.9% saline solution was administered three times a day.” NCT02577393 ↗ “Patients with known allergy to one of the drugs may be treated with oral Gentamycin (2.5mg/KgX3/d) for 3 weeks instead of the allergenic drug.” NCT02033408 ↗ “Clindamycin 2700mg+gentamycin 240mg+ 250ml sterile saline solution i.v. once a day until clinical improvement” NCT02309346 ↗ “an impirical antibiotic (gentamycin 80 mg).” NCT03007225 ↗ “Clindamycin 600 mg + Gentamycin 2 mg/kg.” NCT04438655 ↗ “Gentamycin-80mg in 60ml sterile water” NCT04285320 ↗ NCT03475680 ↗ NCT00465530 ↗ NCT01945450 ↗ NCT01372371 ↗ NCT00671541 ↗ NCT03491540 ↗ NCT04839653 ↗ NCT03688659 ↗ NCT03157388 ↗ NCT04753723 ↗
Known as	Gentamycin-Gentamicin	“Gentamycin-Gentamicin®” NCT02033408 ↗
Known as	GMS	“AppliGel-G is a topically applied hydrogel formulation of gentamicin sulfate (GMS).” NCT02036528 ↗
Known as	Hexamycin	“gentamycin 40 mg ("Hexamycin®"), solution” NCT03157388 ↗ 1 “gentamycin 40 mg ("Hexamycin®")” NCT01633762 ↗
Action	Restore	“gentamicin was shown to restore functional dystrophin in a mouse model of DMD.” NCT00005574 ↗
Modality	Small molecule	“aminoglycoside antibiotics (gentamicin)” NCT00484055 ↗
Route	Intravenous	“Gentamicin will be given intravenously (through a vein) once a day for 14 days.” NCT00005574 ↗
Target	CFTR	“Suppression of stop mutations in the CFTR gene with parenteral gentamicin” NCT00376428 ↗