Reduction of Bacterial Resistance With Inhaled Antibiotics in the Intensive Care Unit

Phase 0 Completed 47 enrolled Stony Brook University

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study was : * to determine the effect of inhaled antibiotics on airway bacteria in ventilated patients * to determine the effect of inhaled antibiotics on respiratory infection

Timeline

Start: 2001-12
Primary completion: 2002-12
Completion: 2002-12

Publications

Palmer LB, Smaldone GC. Reduction of bacterial resistance with inhaled antibiotics in the intensive care unit. Am J Respir Crit Care Med. 2014 May 15;189(10):1225-33. doi: 10.1164/rccm.201312-2161OC.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Gentamicin	Small molecule	80 mg	Inhaled
Subject	Vancomycin	Other / unclassified	120 mg	Inhaled

Reduction of Bacterial Resistance With Inhaled Antibiotics in the Intensive Care Unit

Summary

Timeline

Publications

Drugs

Indications