drugset / Trial / NCT07704398

Effect of Corticosteroid Injection in Symptomatic Pulpitis Cases

NCT07704398

Completed 100 enrolled Istanbul Medipol University Hospital
RandomizedParallel-groupSingle-blindDiagnostic

Summary

This randomized clinical trial compared standard single-visit root canal treatment with adjunctive submucosal betamethasone and gentamicin in 100 patients with symptomatic irreversible pulpitis, assessing postoperative pain and inflammatory biomarkers (IL-1β, MMP-9, and RANKL).

Timeline

Start
2023-10-23
Primary completion
2026-04-23
Completion
2026-04-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Betamethasone Other / unclassified Other
Subject Gentamicin Small molecule Other