drugset / Trial / NCT03931408

Gentamicin Bladder Instillation in Individuals With Spinal Cord Injury Having Chronic Urinary Tract Infections

NCT03931408

Phase 2 Completed 6 enrolled University of Louisville
RandomizedCrossoverQuadruple-blindPrevention

Summary

Participants will undergo daily gentamicin bladder instillations to determine if its use will reduce the rate of symptomatic urinary tract infections (UTIs) as well as the use of oral and intravenous antibiotics in adults with chronic spinal cord injury (SCI) who have recurrent UTIs. Participants are randomized into one of three groups: 1) Gentamicin and saline instillation 2) Saline only instillation 3) Standard of care, no instillation.

Timeline

Start
2019-02-19
Primary completion
2020-07-14
Completion
2020-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Gentamicin Small molecule 480 mg Other

Indications