drugset / Trial / NCT03475680
Mechanical Bowel Preparation and Oral Antibiotics Before Colon Cancer Surgery
RandomizedParallel-groupDouble-blindPrevention
Summary
This study aims to demonstrate that a preoperative combination of mechanical bowel preparation and oral antibiotics, before elective laparoscopic colon cancer surgery, is associated with a reduction of postoperative surgical site infection rate, as compared to mechanical bowel preparation alone, oral antibiotics alone, or no colonic preparation. Our Hypothesis is that a preoperative colonic preparation including a combination of mechanical bowel preparation and oral antibiotics before elective laparoscopic colon cancer surgery is associated with a reduced rate of 30-day postoperative surgical site infection, as compared to mechanical bowel preparation alone, oral antibiotics alone, or no colonic preparation.
Timeline
- Start
- 2018-08-08
- Primary completion
- 2021-08-26
- Completion
- 2022-03-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gentamicin | Small molecule | 80 mg | Oral |
| Subject | Ornidazole | Other / unclassified | 1 g | Oral |
| Subject | Sennosides | Unknown | — | — |