drugset / Trial / NCT04039750

Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis

NCT04039750

Phase 2 Active not recruiting 200 enrolled Prisma Health-Upstate
RandomizedParallel-groupSingle-blindTreatment

Summary

The proposed study will investigate whether antibiotic irrigation using a gentamicin/clindamycin solution during laparoscopic appendectomy is superior in preventing postoperative wound infections and IAA in perforated appendicitis compared to suction without irrigation. This will be the first prospective study to compare these two options in pediatric PA.

Timeline

Start
2019-07-25
Primary completion
2026-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Clindamycin Unknown
Subject Gentamicin Small molecule

Indications