drugset / Trial / NCT01372371
Efficacy of Local Powder Prophylactics
RandomizedParallel-groupSingle-blindPrevention
Summary
Hypothesis: Directly applying antibiotic powder onto the site of surgery along with perioperative intravenous antibiotics, before closing the wound, is more effective than intravenously applied perioperative antibiotics alone in controlling post-operative wound infection. The investigators also think powders that control both gram positive and gram negative bacteria are more beneficial.
Timeline
- Start
- 2011-06
- Primary completion
- 2012-06
- Completion
- 2013-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Gentamicin | Small molecule | — | — |
| Comparator | Vancomycin | Other / unclassified | 500 mg | Other |
| Comparator | Cefuroxime | Small molecule | 750 mg | Intravenous |