drugset / Trial / NCT01372371

Efficacy of Local Powder Prophylactics

NCT01372371

Unknown 1844 enrolled Ganga Hospital
RandomizedParallel-groupSingle-blindPrevention

Summary

Hypothesis: Directly applying antibiotic powder onto the site of surgery along with perioperative intravenous antibiotics, before closing the wound, is more effective than intravenously applied perioperative antibiotics alone in controlling post-operative wound infection. The investigators also think powders that control both gram positive and gram negative bacteria are more beneficial.

Timeline

Start
2011-06
Primary completion
2012-06
Completion
2013-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Gentamicin Small molecule
Comparator Vancomycin Other / unclassified 500 mg Other
Comparator Cefuroxime Small molecule 750 mg Intravenous

Indications