drugset / Trial / NCT02395614

Surgical Site Infection With 0.05% Chlorhexidine (CHG) Compared to Triple Antibiotic Irrigation

NCT02395614

Completed 88 enrolled Vanderbilt University Medical Center
RandomizedSingle-groupDouble-blindTreatment

Summary

The investigators intend to perform a prospective randomized study and compare the incidence of surgical wound infection between mastectomy wounds irrigated with triple antibiotic solution (one side) and 0.05% CHG (opposite side) in patients undergoing bilateral breast reconstruction. Each patient will receive triple antibiotic solution on one breast and the CHG on the other breast.

Timeline

Start
2015-12
Primary completion
2020-12
Completion
2020-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bacitracin Unknown 50000 iu Other
Comparator Cefazolin Small molecule 1 g Other
Subject Chlorhexidine Small molecule 0.05 % Other
Comparator Gentamicin Small molecule 80 mg Other

Indications