Drugs / Chlorhexidine
Chlorhexidine
also known as
CHX · chlorhexidine gluconate · CHG · chlorhexidine digluconate · chlorohexidine · Hibiclens · ChloraPrep · Chlorhexidin · +26 more
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 05 trials | ||||||
| Phase 0 | NCT07461155 | Jul 2026 → Jul 2027 expected | gingivitis | Ministry of Higher Education, Malaysia | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT03384537 | Feb 2024 → Oct 2026 expected | tooth disorder | Cairo University | Recruiting | No outcome recorded |
| Phase 0 | NCT05024760 | Jul 2022 → Nov 2025 overdue | mucositis, periodontitis, prosthesis-related infectious disease | Madigan Army Medical Center | Recruiting | No outcome recorded |
| Phase 0 | NCT04679558 | Sep 2020 → Jul 2021 | dental caries | Cairo University | Completed | No outcome recorded |
| Phase 0 | NCT02990013 | Dec 2018 → Dec 2019 | toxic dermatosis | University of Miami | Completed | No outcome recorded |
| Phase 11 trial | ||||||
| Phase 1 | NCT00841074 | Jan 2006 → Jul 2011 | pneumonia | University of Louisville | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT04385680 | May 2020 → Mar 2022 | endometritis, skin infection | Zagazig University | Completed | No outcome recorded |
| Phase 219 trials · 1 met primary · 3 missed | ||||||
| Phase 2 | NCT07481955 | Mar 2026 → Mar 2027 expected | bacterial vaginosis | Freya Biosciences ApS | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06792812 | Jan → Apr 2025 | chronic gingivitis | Al-Mustansiriyah University | Completed | No outcome recorded |
| Phase 2 | NCT06120140 | Feb 2024 → May 2027 expected | non-small cell lung carcinoma | Janssen Research & Development, LLC | Active not recruiting | Met primary |
| Phase 2 | NCT05505214 | Sep 2023 → Sep 2025 | radiodermatitis | Montefiore Medical Center | Withdrawn | No outcome recorded |
| Phase 2 | NCT06002295 | Sep 2020 → Sep 2021 | neonatal sepsis, omphalitis | Sheikh Zayed Federal Postgraduate Medical Institute | Completed | No outcome recorded |
| Phase 2 | NCT04344236 | Apr → May 2020 | COVID-19 | NYU Langone Health | Withdrawn | No outcome recorded |
| Phase 2 | NCT04453124 | Nov 2019 | chronic ulcer of skin, yaws | Oriol Mitja | Completed | No outcome recorded |
| Phase 2 | NCT03503370 | Jan 2019 → Dec 2022 | ulcer of lower limbs | VA Office of Research and Development | Completed | Missed primary |
| Phase 2 | NCT03614429 | Jun → Dec 2018 | — | Cairo University | Unknown | No outcome recorded |
| Phase 2 | NCT03484507 | Jan 2018 → Nov 2022 | Acanthamoeba keratitis | University of California, San Francisco | Completed | Missed primary |
| Phase 2 | NCT02678104 | Oct 2016 → Jun 2017 | alveolar periostitis | Riyadh Colleges of Dentistry and Pharmacy | Unknown | No outcome recorded |
| Phase 2 | NCT02788786 | Jun → Nov 2016 | periodontitis | Johns Hopkins Bloomberg School of Public Health | Completed | No outcome recorded |
| Phase 2 | NCT03334461 | Dec 2015 → Mar 2022 | enamel caries, gingivitis | University of Rijeka | Completed | No outcome recorded |
| Phase 2 | NCT02252588 | Sep 2014 → Dec 2019 | chronic obstructive pulmonary disease | University of Minnesota | Completed | Missed primary |
| Phase 2 | NCT02396329 | Jun 2014 → Jun 2015 | — | Ain Shams Maternity Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT02077920 | Mar 2014 → Jun 2019 | — | General Hospital of Shenyang Military Region | Completed | No outcome recorded |
| Phase 2 | NCT02132546 | Feb → Oct 2011 | — | dott. Lorenzo Bevilacqua | Completed | No outcome recorded |
| Phase 2 | NCT00425451 | Aug 2008 → Jan 2009 | periodontitis | Dexcel Pharma Technologies Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT00266448 | Jan 2001 → Apr 2004 | — | Heidelberg University | Completed | No outcome recorded |
| Phase 2/35 trials · 1 missed | ||||||
| Phase 2/3 | NCT06900881 | Apr → Sep 2025 overdue | gingivitis | Al-Mustansiriyah University | Recruiting | No outcome recorded |
| Phase 2/3 | NCT03883828 | Jun 2019 → Dec 2021 | radiodermatitis | Montefiore Medical Center | Completed | Mixed |
| Phase 2/3 | NCT03836781 | Apr 2018 → Jun 2019 | chronic periodontitis | Amirhossein Farahmand | Completed | No outcome recorded |
| Phase 2/3 | NCT04399161 | Feb → Dec 2017 | — | Dr. Krupa NC | Completed | Missed primary |
| Phase 2/3 | NCT01723501 | Nov 2012 → ? | neonatal sepsis | All India Institute of Medical Sciences | Withdrawn | No outcome recorded |
| Phase 323 trials · 2 met primary · 3 missed | ||||||
| Phase 3 | NCT07803484 | Sep 2026 → Mar 2028 expected | gingivitis | Colgate Palmolive | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07559877 | Apr 2026 → Jun 2027 expected | nasopharyngeal carcinoma | Jiangxi Provincial Cancer Hospital | Recruiting | No outcome recorded |
| Phase 3 | NCT06732466 | Mar → Apr 2025 | gingivitis, smooth surface dental caries | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT06702878 | Dec 2024 → Apr 2026 | infectious disease | Ondine Biomedical Inc. | Completed | No outcome recorded |
| Phase 3 | NCT06489431 | Dec 2023 → May 2026 overdue | erectile dysfunction, prosthesis-related infectious disease | Rush University Medical Center | Active not recruiting | Met primary |
| Phase 3 | NCT03700788 | May 2023 → Jun 2025 | periodontitis | University of Southern California | Unknown | No outcome recorded |
| Phase 3 | NCT05084378 | Mar 2022 → Aug 2024 | periprosthetic joint infection | McMaster University | Completed | No outcome recorded |
| Phase 3 | NCT07351370 | Jan → Jul 2022 | periodontal disorder | Dental School | Completed | No outcome recorded |
| Phase 3 | NCT05532241 | Nov 2021 → May 2025 overdue | gingivitis, malposition of teeth with or without hypodontia/oligodontia | University of Rijeka | Active not recruiting | No outcome recorded |
| Phase 3 | NCT04256798 | Nov 2020 → Oct 2025 overdue | pneumonia, skin infection | University of Birmingham | Recruiting | No outcome recorded |
| Phase 3 | NCT03925155 | May 2020 → May 2022 | — | Montefiore Medical Center | Withdrawn | No outcome recorded |
| Phase 3 | NCT03838575 | Mar 2019 → May 2023 | — | University of Birmingham | Unknown | No outcome recorded |
| Phase 3 | NCT02753387 | May 2016 → Sep 2018 | primary bacterial infectious disease | Rennes University Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02414581 | Apr 2015 → Aug 2016 | neutropenia | Hospital Regional de Alta Especialidad del Bajio | Completed | No outcome recorded |
| Phase 3 | NCT02208154 | Dec 2013 → Oct 2017 | bacterial infectious disease with sepsis | MJM Bonten | Completed | Missed primary |
| Phase 3 | NCT01989416 | Dec 2013 → Jan 2015 | bacterial infectious disease | Mahidol University | Completed | No outcome recorded |
| Phase 3 | NCT01361997 | Jun 2011 → Aug 2012 | infectious disease | University of Guanajuato | Completed | No outcome recorded |
| Phase 3 | NCT01528852 | May 2011 → Sep 2014 | omphalitis | Johns Hopkins Bloomberg School of Public Health | Completed | Missed primary |
| Phase 3 | NCT00682006 | Jan 2008 → Sep 2009 | omphalitis | Aga Khan University | Completed | Met primary |
| Phase 3 | NCT00560599 | Apr 2007 → Feb 2012 | methicillin-resistant staphylococcus aureus infectious disease | loren g miller | Completed | No outcome recorded |
| Phase 3 | NCT00136370 | Apr 2004 → Nov 2007 | infectious disease with sepsis, puerperal infection | Centers for Disease Control and Prevention | Unknown | Missed primary |
| Phase 3 | NCT00067340 | Apr 2003 → Jul 2006 | dental caries | University of Washington | Terminated | No outcome recorded Stop: Enrollment |
| Phase 3 | NCT00004640 | May 1998 → May 2008 | dental caries, periodontal disorder | University of Washington | Completed | No outcome recorded |
| Phase 441 trials · 4 met primary · 1 missed | ||||||
| Phase 4 | NCT06397781 | Jan 2031 → Dec 2035 expected | atopic eczema | Boston Children's Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07807397 | Sep 2026 → Sep 2027 expected | dental caries, gingivitis | Colgate Palmolive | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07824388 | Mar → Jul 2026 | gingivitis | University of Barcelona | Completed | No outcome recorded |
| Phase 4 | NCT07814898 | Feb → May 2026 | gingivitis | University of Science and Technology, Yemen | Completed | No outcome recorded |
| Phase 4 | NCT07311343 | Jan → Dec 2026 expected | hemorrhagic disease, pneumonia | Beijing Tiantan Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07124650 | Sep 2025 → Dec 2026 expected | — | Saint Petersburg State University, Russia | Recruiting | No outcome recorded |
| Phase 4 | NCT06598514 | Dec 2024 → Apr 2026 overdue | urinary tract infection | Oregon Health and Science University | Active not recruiting | No outcome recorded |
| Phase 4 | NCT07048899 | Sep 2024 → Dec 2025 overdue | — | The University of Texas Health Science Center at Tyler | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT07451678 | Jul → Aug 2024 | blepharitis | Instituto de Oftalmología Fundación Conde de Valenciana | Completed | No outcome recorded |
| Phase 4 | NCT04171817 | May 2023 → Sep 2025 | Clostridium difficile colitis, Pseudomonas aeruginosa infectious disease, methicillin-resistant staphylococcus aureus infectious disease | Johns Hopkins Bloomberg School of Public Health | Completed | No outcome recorded |
| Phase 4 | NCT07270952 | Jan → Apr 2023 | gingivitis | Stony Brook University | Completed | No outcome recorded |
| Phase 4 | NCT04337749 | Nov → Dec 2022 | — | Mahidol University | Withdrawn | No outcome recorded |
| Phase 4 | NCT05211622 | Mar → Dec 2022 | stomatitis | University of Palermo | Unknown | No outcome recorded |
| Phase 4 | NCT04027179 | Aug 2020 → Dec 2021 | periodontitis | University of Taubate | Unknown | No outcome recorded |
| Phase 4 | NCT04223076 | Mar → Dec 2019 | periodontitis | University of Oslo | Unknown | No outcome recorded |
| Phase 4 | NCT03757143 | Jan → Sep 2019 | — | Poitiers University Hospital | Completed | Met primary |
| Phase 4 | NCT03962907 | Jan 2019 → Mar 2020 | staphylococcus aureus infection | Lindenhofgruppe AG | Completed | No outcome recorded |
| Phase 4 | NCT03560193 | Sep 2018 → May 2022 | — | Poitiers University Hospital | Completed | Missed primary |
| Phase 4 | NCT03741894 | Sep 2018 → Sep 2020 | alveolar periostitis, impacted teeth, multiple, pulpitis | University of Pecs | Unknown | No outcome recorded |
| Phase 4 | NCT03412734 | May 2018 → Aug 2019 | — | TriHealth Inc. | Terminated | Met primary Stop: Enrollment |
| Phase 4 | NCT02202304 | Sep 2017 → Sep 2019 | dental caries, periodontal disorder | Rosa Moreno Lopez | Withdrawn | No outcome recorded |
| Phase 4 | NCT05178823 | Jun 2017 → Sep 2019 | dental caries, gingival disorder | Semmelweis University | Completed | No outcome recorded |
| Phase 4 | NCT03103204 | Jan → Jul 2017 | morbid obesity, periodontitis | University of Taubate | Completed | No outcome recorded |
| Phase 4 | NCT03940729 | Dec 2016 → Jan 2020 | — | Lund University | Completed | No outcome recorded |
| Phase 4 | NCT02606565 | Jul 2016 → Oct 2020 | infectious disease with sepsis, omphalitis | Makerere University | Completed | No outcome recorded |
| Phase 4 | NCT02695901 | Mar → Dec 2016 | — | Federal University of Santa Maria | Unknown | No outcome recorded |
| Phase 4 | NCT02572791 | Oct 2015 → Nov 2024 | methicillin-resistant staphylococcus aureus infectious disease, skin disease caused by bacterial infection | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 4 | NCT03639363 | Aug 2015 → Apr 2016 | nosocomial infection | University Of Perugia | Completed | Met primary |
| Phase 4 | NCT04868513 | Jan 2015 → Oct 2017 | — | Biochemical and Microbiology Laboratory, Faculty of Dentistry, Autonomous University of San Luis Pot | Completed | No outcome recorded |
| Phase 4 | NCT02279381 | Nov 2014 → Nov 2015 | — | Aga Khan University | Completed | No outcome recorded |
| Phase 4 | NCT04218799 | Aug 2014 → Sep 2015 | — | University of Maryland, Baltimore | Completed | No outcome recorded |
| Phase 4 | NCT02032394 | Jul 2013 → Feb 2014 | bacteriuria, nosocomial infection, urinary tract infection | Mashhad University of Medical Sciences | Unknown | No outcome recorded |
| Phase 4 | NCT02479347 | Mar 2013 → Sep 2016 | breast neoplasm, skin infection | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | Completed | No outcome recorded |
| Phase 4 | NCT01844141 | Jan → Apr 2013 | nail disorder | Universidad Complutense de Madrid | Unknown | No outcome recorded |
| Phase 4 | NCT01883596 | Oct 2012 → Oct 2016 | — | Sinaloa Pediatric Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT04222699 | Sep 2012 → Nov 2014 | — | VA Office of Research and Development | Completed | No outcome recorded |
| Phase 4 | NCT02124655 | Sep 2012 → Jun 2013 | periodontitis | University of Santiago de Compostela | Completed | Met primary |
| Phase 4 | NCT02215460 | Apr 2012 → Mar 2014 | periodontitis | University of Taubate | Completed | No outcome recorded |
| Phase 4 | NCT02062047 | Dec 2007 → Mar 2010 | chronic periodontitis, type 2 diabetes mellitus | University of Guarulhos | Completed | No outcome recorded |
| Phase 4 | NCT01213550 | Mar 2006 → Dec 2007 | — | Ege University | Completed | No outcome recorded |
| Phase 4 | NCT00198679 | Mar 2004 → Mar 2005 | skin infection | Johns Hopkins Bloomberg School of Public Health | Completed | No outcome recorded |
| Phase not applicable55 trials · 3 met primary · 4 missed | ||||||
| — | NCT07868549 | Jun → Sep 2026 overdue | — | University of Zagreb | Enrolling by invitation | No outcome recorded |
| — | NCT07611123 | Apr → May 2026 | — | Biointelligent Technology Systems SL | Completed | No outcome recorded |
| — | NCT07307716 | Feb → Oct 2026 expected | gingivitis, smooth surface dental caries | Riyadh Elm University | Not yet recruiting | No outcome recorded |
| — | NCT07490873 | Jan → Jul 2026 | — | University of Baghdad | Completed | No outcome recorded |
| — | NCT07801417 | Dec 2025 overdue | chronic periodontitis | Al-Azhar University | Active not recruiting | No outcome recorded |
| — | NCT07215156 | Oct 2025 → Apr 2026 overdue | chronic periodontitis | Kafrelsheikh University | Not yet recruiting | No outcome recorded |
| — | NCT07115784 | Jul 2025 → Jan 2026 | gingival overgrowth, tooth hard tissue disease | Khyber Medical University Peshawar | Completed | No outcome recorded |
| — | NCT07031388 | Jul → Sep 2025 | gingival disorder | Ramziyah Hayder Bakr | Completed | No outcome recorded |
| — | NCT07540624 | May 2025 → Jun 2026 overdue | periodontitis | Inonu University | Active not recruiting | No outcome recorded |
| — | NCT07058727 | May → Nov 2025 overdue | — | Cukurova University | Recruiting | No outcome recorded |
| — | NCT07138586 | Jan → Apr 2025 | ulcerative stomatitis | National Research Centre, Egypt | Completed | No outcome recorded |
| — | NCT06625645 | Jan → May 2025 overdue | dental pulp necrosis, periapical periodontitis | Mahy Abdel Raouf Aly Kamar | Not yet recruiting | No outcome recorded |
| — | NCT06875440 | Sep 2024 → Jan 2025 overdue | periodontal disorder | Islamic Azad University, Sanandaj | Enrolling by invitation | No outcome recorded |
| — | NCT06541145 | Aug → Oct 2024 | — | Duke University | Completed | No outcome recorded |
| — | NCT07123792 | Jun 2024 → May 2025 | periodontal disorder | HITEC-Institute of Medical Sciences | Completed | No outcome recorded |
| — | NCT07482007 | Apr 2024 → Jan 2026 | — | Tanta University | Completed | No outcome recorded |
| — | NCT06834711 | Feb → Dec 2024 | chronic apical periodontitis | Cukurova University | Completed | No outcome recorded |
| — | NCT06171594 | Dec 2023 → Jul 2024 | tooth erosion, non-bacterial | University of Portsmouth | Unknown | No outcome recorded |
| — | NCT06077032 | Nov 2023 → Oct 2025 | common wart | Assiut University | Unknown | No outcome recorded |
| — | NCT05803590 | May → Jul 2023 | gingivitis | Cairo University | Unknown | No outcome recorded |
| — | NCT04781036 | May 2023 → Dec 2024 | infectious disease | Mahidol University | Unknown | No outcome recorded |
| — | NCT07570927 | Apr → Nov 2022 | — | Masaryk University | Completed | No outcome recorded |
| — | NCT05548361 | Apr 2022 → Dec 2024 | periodontitis | Cukurova University | Completed | No outcome recorded |
| — | NCT06191497 | Mar 2022 → Oct 2023 | periodontitis | University of Rijeka | Unknown | No outcome recorded |
| — | NCT05846139 | Jan → Nov 2022 | periodontitis | Tuscan Dental Institute | Completed | No outcome recorded |
| — | NCT05122169 | Dec 2021 → Dec 2025 | — | Seoul National University Hospital | Unknown | No outcome recorded |
| — | NCT05016713 | Jun 2021 → Jul 2023 | — | Cairo University | Unknown | No outcome recorded |
| — | NCT05543603 | Apr 2021 → Jan 2022 | COVID-19 | FISABIO Foundation | Completed | No outcome recorded |
| — | NCT04733196 | Oct → Dec 2020 | gingivitis | Plovdiv Medical University | Completed | No outcome recorded |
| — | NCT04707742 | Jun 2020 → Sep 2021 | COVID-19 | FISABIO Foundation | Completed | Missed primary |
| — | NCT04403971 | May → Oct 2020 | pneumonia | National Cheng-Kung University Hospital | Completed | No outcome recorded |
| — | NCT04009616 | Mar → Jun 2019 | — | Damascus University | Completed | No outcome recorded |
| — | NCT04074915 | Dec 2018 → Apr 2019 | chronic periodontitis | Institute of Dental Sciences, Bareilly, Uttar Pradesh, India | Completed | No outcome recorded |
| — | NCT03526770 | May → Jul 2018 | tooth hard tissue disease | Dr Meru S | Completed | No outcome recorded |
| — | NCT03510962 | Apr → Jul 2018 | tooth hard tissue disease | Dr Meru S | Completed | No outcome recorded |
| — | NCT03064191 | Sep 2017 → Mar 2018 | tooth disorder | rayan rabie dahab | Unknown | No outcome recorded |
| — | NCT03492827 | Jun 2017 → Jun 2019 | esophageal cancer, gastric cancer | Peking University Third Hospital | Unknown | No outcome recorded |
| — | NCT03442218 | Jun → Aug 2017 | endometritis | Saint Thomas Hospital, Panama | Completed | No outcome recorded |
| — | NCT03009006 | Jan → Oct 2017 | dental pulp necrosis | Cairo University | Unknown | No outcome recorded |
| — | NCT02950246 | Nov 2016 → Jul 2018 | prosthesis-related infectious disease | Hôpital Raymond Poincaré | Unknown | Met primary |
| — | NCT02709785 | Mar 2016 → May 2017 | gingivitis, periodontitis | St. Louis University | Completed | No outcome recorded |
| — | NCT02395614 | Dec 2015 → Dec 2020 | breast cancer | Vanderbilt University Medical Center | Completed | No outcome recorded |
| — | NCT02027324 | Jun 2015 → Feb 2017 | — | Brigham and Women's Hospital | Withdrawn | No outcome recorded |
| — | NCT02375178 | Aug → Oct 2014 | periodontal disorder, smooth surface dental caries | Universidade do Vale do Sapucai | Completed | No outcome recorded |
| — | NCT02063867 | Apr 2014 → Feb 2019 | methicillin-resistant staphylococcus aureus infectious disease, nosocomial infection | University of California, Irvine | Completed | Missed primary |
| — | NCT02202577 | Mar 2014 → Jul 2016 | — | Case Western Reserve University | Completed | Missed primary |
| — | NCT02115776 | Jan 2014 → Apr 2015 | bacterial infectious disease | University of Santiago de Compostela | Completed | No outcome recorded |
| — | NCT02126267 | Jan 2013 → Feb 2014 | chronic periodontitis | Centro Universitario de Lavras | Completed | No outcome recorded |
| — | NCT01886001 | Nov 2012 → May 2013 | — | University of Virginia | Completed | No outcome recorded |
| — | NCT01568944 | Mar 2012 → Sep 2014 | chronic periodontitis | Augusta University | Completed | No outcome recorded |
| — | NCT02131922 | Sep 2009 → Sep 2014 | chronic periodontitis, hypertensive disorder | Jagiellonian University | Unknown | Met primary |
| — | NCT00719329 | Aug 2008 → Sep 2009 | infectious disease | Johns Hopkins Bloomberg School of Public Health | Completed | Met primary |
| — | NCT00247897 | Nov 2005 → Oct 2007 | skin disease caused by bacterial infection | University of British Columbia | Completed | No outcome recorded |
| — | NCT00947518 | Aug 2005 → Feb 2006 | fetal growth restriction, neonatal sepsis | All India Institute of Medical Sciences | Completed | Missed primary |
| — | NCT00223002 | Nov 2004 → Jan 2007 | — | University of Saskatchewan | Completed | No outcome recorded |
| Phase not stated1 trial | ||||||
| — | NCT04035161 | Apr → Dec 2019 | — | Becton, Dickinson and Company | Completed | No outcome recorded |
| Comparator or background therapy137 trials | ||||||
| Phase 0 | NCT03957291 Comparator | Aug 2019 → Aug 2022 | — | Assiut University | Unknown | No outcome recorded |
| Phase 0 | NCT03571100 Comparator | May 2018 → May 2019 | age-related macular degeneration, retinal vein occlusion | Mid Atlantic Retina | Unknown | No outcome recorded |
| Phase 0 | NCT03209115 Comparator | Jul → Sep 2017 | — | Cairo University | Unknown | No outcome recorded |
| Phase 1 | NCT07662226 Comparator | Aug → Nov 2026 expected | gingival disorder | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06505759 Comparator | Jul 2024 → Jul 2025 overdue | periodontal disorder | Krishnadevaraya College of Dental Sciences & Hospital | Recruiting | No outcome recorded |
| Show all 137 trials opens the full record — a long page | ||||||
News releases announcing trial results or a regulatory action · 8
| Date | Issuer | Release |
|---|---|---|
| 2025-06-10 | Ondine Biomedical Inc. | Results Ondine presents ground-breaking findings in the fight against multidrug-resistant pathogens at 19th World Congress of the International Photodynamic Association ondinebio.com ↗
Photodisinfection shown to enhance the potency of many antibiotics, including vancomycin, ciprofloxacin, and tetracycline, as well as antiseptics such as benzalkonium chloride and chlorhexidine. |
| 2023-10-23 | Ondine Biomedical Inc. | Results 66.5% reduction in spine surgery infection rate ondinebio.com ↗
The VGH spine group, led by Dr. John Street, presented its research findings showing a significant and sustained reduction of surgical site infections (SSIs) in spine surgery patients using this universal pre-surgical protocol. |
| 2020-03-13 | Ondine Biomedical Inc. | Results VGH Awarded for Photodisinfection Therapy Research ondinebio.com ↗
When combined with chlorhexidine body wipes prior to surgery, the pilot saw SSIs decrease by 39 per cent and the number of readmissions due to SSIs decline from four to 1.25 cases per month. |
| 2020-03-02 | Ondine Biomedical Inc. | Results Surgical Site Infection Reduction Abstract Presented at CSS 2020 ondinebio.com ↗
From 2011 to 2014, photodynamic nasal decolonization and chlorhexidine skin decontamination (PDT/CHG) was applied to all elective and emergency spine cases, with the sSSI rate falling from 7.2% to 2%. |
| 2020-03-02 | Ondine Biomedical Inc. | Results Pre-op decolonization Abstract Presented at CSS 2020 ondinebio.com ↗
Pre-operative decolonization does not adversely affect the microbiologic spectrum of spine surgical site infection |
| 2019-04-03 | Sunstar Americas | Regulatory Centre Spécialités Pharmaceutiques recalls PAROEX 0,12% sunstar.com ↗
Centre Spécialités Pharmaceutiques (CSP) procède à un rappel de lots de PAROEX 0,12 POUR CENT, solution pour bain de bouche en France |
| 2016-04-29 | GlaxoSmithKline | Regulatory European agency endorses antiseptic gel, developed through GSK and Save the Children partnership, for newborn umbilical cord infections in developing countries gsk.com ↗
has today been granted a positive scientific opinion from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA). |
| 2015-10-12 | GlaxoSmithKline | Regulatory GSK submits regulatory application for chlorhexidine gel for the prevention of umbilical cord infections in newborn babies gsk.com ↗
GSK today announced that it has submitted a regulatory application to the European Medicines Agency (EMA) for its antiseptic chlorhexidine gel (7.1% chlorhexidine digluconate gel, equivalent to 4% chlorhexidine) for the prevention of umbilical cord infections (omphalitis) in newborn babies. |
All press releases naming this drug 11 releases
Evidence & citations 38 cited values
Every value below carries the sentence it was read from. 299 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | chlorhexidine | “This is a multi-centre, blinded, parallel-group, placebo-controlled randomised clinical trial that tests the effect of four mouthwashes (cetylpyridinium chloride,...” PMID 34937855 ↗ Dec 2021281“Kloroben topical spray containing chlorhexidine gluconate and benzydamine hydrochloride is applied to the surgical site immediately after impacted mandibular third molar...” NCT07416136 ↗ “Extraoral Bacitracin-Neomycin ointment and 10% povidone-iodine, together with intraoral benzydamine hydrochloride oral spray and chlorhexidine gluconate mouthwash, administered...” NCT07801157 ↗ “Previous studies revealed efficacy of topical choices, including benzoyl peroxide gel, clindamycin-benzoyl peroxide gel, glycopyrrolate cream, erythromycin gel, clindamycin...” NCT04332796 ↗ “Participants will be exposed to chlorohexidine based mouthwash. and will be instructed to use 10 ml of 0.12% chlorhexidine based mouthwash 2 times per day for 1 minute; such a...” NCT04566120 ↗ “Postoperative instructions were given, antibiotics were prescribed for 7 days (amoxicillin 500 mg t.i.d), analgesics to relieve from pain (Paracetamol 750 mg) and chlorhexidine...” NCT02922075 ↗ “This study aimed to study the efficacy of chlorhexidine scrub, zinc oxide nanoparticles (ZnO-NPs) socks and the combination of chlorhexidine scrub and ZnO-NPs socks in...” NCT04337749 ↗ “Chlorhexidine digluconate 2 % solution (Cavity Cleanser, Bisco, USA). Each tooth will receive two drops of cavity cleanser with a micro brush, equivalent to a dose of 10 mg of...” NCT03186261 ↗ “The objective of this study was to determine the efficacy of Aloe vera gel at 80% compared to 0.12% Chlorhexidine gel to alleviate the effects derived from any orthodontic treatment” NCT03633292 ↗ “2% aqueous base chlorhexidine (10 ml single dose containers). Use for the preparation of the skin before insertion of the central venous catheters and at each dressing change.” NCT03489512 ↗ “The use of chlorhexidine for vaginal cleansing before a cesarean delivery in patients with rupture of membranes reduced the risk for endometritis and puerperal fever.” PMID 35051671 ↗ Jan 2022 |
| Known as | Bexident | “Bexident® (0.12% chlorhexidine solution)” NCT01883596 ↗ |
| Known as | Cavity Cleanser | “Chlorhexidine digluconate 2 % solution (Cavity Cleanser, Bisco, USA). Each tooth will receive two drops of cavity cleanser with a micro brush, equivalent to a dose of 10 mg of...” NCT03186261 ↗ |
| Known as | Cervitec | “Cervitec chlorhexidine varnish” NCT00066040 ↗ |
| Known as | CHG | “superiority of chlorhexidine (CHG)-alcohol over povidone iodine (PVI)-alcohol, the two most common alcohol-based antiseptic solutions used worldwide, is controversial.” PMID 31213447 ↗ Jun 20196“0.05% chlorhexidine gluconate (CHG) (Irrisept®) (Irrimax Corp, Lawrenceville, GA, USA), has shown promise as an alternative irrigant” PMID 39434728 ↗ Sep 2024 “Daily chlorhexidine (CHG) shower or CHG cloth bath for all non-critical care patients.” NCT02063867 ↗ “soap-like solution of 4% chlorhexidine (CHG) followed by water rinsing (CHGwr)” PMID 30267930 ↗ Sep 2018 “using chlorhexidine gluconate (CHG) in an alcohol-based solution” NCT03838575 ↗ “2% chlorhexidine (CHG)-70% isopropanol” NCT03757143 ↗ “Chlorhexidine Gluconate (CHG)-alcohol” NCT02202577 ↗ |
| Known as | ChloraPrep | “Chlorhexidine(chloraprep) has been proven to be better than povidone iodine solution for skin preparation before epidural catheter and intravascular device insertion” NCT00896402 ↗1“Groupe B: (1) 2% (w/v) CHG-70% (v/v) isopropanol (ChloraPrep™, CareFusion); (2) InsyteTM AutoguardTM BC Winged, BD” NCT03757143 ↗ |
| Known as | Chlorhexidin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01400308 ↗ |
| Known as | chlorhexidine acetate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00357877 ↗ |
| Known as | Chlorhexidine Diacetate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04365270 ↗ |
| Known as | chlorhexidine digluconate | “Due to the side effects of chlorhexidine digluconate (CHX) mouthrinsing, a spray has been proposed as an alternative method of CHX delivery to the oral cavity.” PMID 16460251 ↗ Feb 20063“Commercial 0.12% chlorhexidine digluconate mouthwash twice daily (each morning and before bedtime during the 21-day study period) after intake of food.” NCT04575948 ↗ “This intervention represents the positive control group of the study and involves the use of a 0.12% chlorhexidine digluconate mouthwash.” NCT07393802 ↗ “Corsodyl® (0.2% chlorhexidine-digluconate; CHX)” NCT05178823 ↗ |
| Known as | Chlorhexidine digluconate 2 % solution | “Chlorhexidine digluconate 2 % solution” NCT03186261 ↗ |
| Known as | Chlorhexidine gel (PERIOPLUS+ FORTE, Curaprox, Curaden) | “Chlorhexidine gel (PERIOPLUS+ FORTE, Curaprox, Curaden)” NCT06894667 ↗ |
| Known as | chlorhexidine gluconate | “Chlorhexidine gluconate(CHX) is a gluconate salt with a broad-spectrum antiseptic action against Gram-Positive, Gram-negative bacteria, aerobes, facultative anaerobes, and...” NCT06077032 ↗15“0.05% chlorhexidine gluconate (CHG) (Irrisept®) (Irrimax Corp, Lawrenceville, GA, USA), has shown promise as an alternative irrigant” PMID 39434728 ↗ Sep 2024 “Chlorhexidine gluconate solution (commonly 0.12%) used as an antimicrobial oral rinse following standard postoperative instructions.” NCT07611123 ↗ “vaginal scrub with 4% chlorhexidine gluconate and 10% povidone-iodine antiseptic solution immediately prior to cesarean section” NCT03925155 ↗ “with 25ml chlorhexidine gluconate soap, (Lifo-Scrub sol 4 % 500ml, B. Braun)” NCT03962907 ↗ “Chlorhexidine Gluconate 0.12 % Mouthwash + benzydamine hydrochloride” NCT04373421 ↗ “A preoperative Chlorhexidine gluconate solution 4.0% (i.e Hibiclens)” NCT02510144 ↗ “using chlorhexidine gluconate (CHG) in an alcohol-based solution” NCT03838575 ↗ “0.2% mouthwash solution of chlorhexidine gluconate.” NCT04723732 ↗ “Chlorhexidine Gluconate vaginal solution 0.05%” NCT04385680 ↗ “Chlorhexidine Gluconate 0.12 % Mouthwash” NCT07393802 ↗ |
| Known as | Chlorhexidine/Thymol varnish | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02202304 ↗ |
| Known as | chlorohexidine | “Participants will be exposed to chlorohexidine based mouthwash. and will be instructed to use 10 ml of 0.12% chlorhexidine based mouthwash 2 times per day for 1 minute; such a...” NCT04566120 ↗2“Patients will be treated with one of two current clinically-used medications, 2% chlorohexidine (intervention) vs. calcium hydroxide (standard-of-care).” NCT03700788 ↗ “Group 2- Chlorohexidine (CHX).” NCT05069246 ↗ |
| Known as | CHX | “The goal of this clinical trial is to evaluate and compare the antiplaque efficacy and patient reported outcome of three commonly used antiseptic mouthwashes - Chlorhexidine...” NCT07490873 ↗26“Chlorhexidine mouthwash is added to the oral hygiene protocol being used beside fluoride-based toothpaste and interdental brushes. CHX mouthwash is used by patients according...” NCT05016713 ↗ “Chlorhexidine gluconate(CHX) is a gluconate salt with a broad-spectrum antiseptic action against Gram-Positive, Gram-negative bacteria, aerobes, facultative anaerobes, and...” NCT06077032 ↗ “Chlorhexidine was developed in 1950 and is the most used anti-plaque agent. However, the long-term usage of chlorhexidine (CHX) is limited by altered taste perception and tooth...” NCT05803590 ↗ “We aimed to assess the effect of umbilical-cord cleansing with 4% chlorhexidine (CHX) solution, with or without handwashing with antiseptic soap, on the incidence of omphalitis...” PMID 22322126 ↗ Feb 2012 “The investigation assessed the clinical effect of a mouthrinse containing chlorhexidine (CHX) and sodium fluoride (NaF) during a 4-day period of non-brushing and a 6-week...” NCT02935322 ↗ “The effects of the resveratrol-based mouthwash will be compared with 0.12% chlorhexidine (CHX) and a placebo mouthwash under standardized conditions without mechanical oral hygiene” NCT07393802 ↗ “The study tests the efficacy of hyaluronic acid (HYL) mouthwash as adjunct to Chlorhexidine (CHX) mouthwash compared to Chlorhexidine mouthwash only in 16 gingivitis patients.” NCT07366398 ↗ “This randomized clinical trial evaluates the efficacy of sodium hypochlorite (NaOCl), chlorhexidine (CHX), and cold saline as hemostatic agents in partial pulpotomy.” NCT07058727 ↗ “Due to the side effects of chlorhexidine digluconate (CHX) mouthrinsing, a spray has been proposed as an alternative method of CHX delivery to the oral cavity.” PMID 16460251 ↗ Feb 2006 “The overall goal is to assess whether 2% Chlorhexidine (CHX) is superior to Calcium Hydroxide in reducing interappointment pain.” NCT03700788 ↗ |
| Known as | clorhexidine | “Clorhexidine Gel (LACER®, Barcelona, Spain) 0.12%, application 2 times / days for 1 month.” NCT03633292 ↗ |
| Known as | Clorhexidine Dental PHB | “Clorhexidine 0,12% (Clorhexidine Dental PHB©) contains clorhexidine (C22H30N10Cl2).” NCT04707742 ↗ |
| Known as | Consepsis | “2% chlorhexidine (Consepsis®, Ultradent) will be applied to the cavity for 20 seconds.” NCT06765330 ↗ |
| Known as | Corsodyl | “Corsodyl® (0.2% chlorhexidine-digluconate; CHX)” NCT05178823 ↗ |
| Known as | Corsodyl Mint | “0.2% CHX (Corsodyl Mint, GlaxoSmithKline, UK)” NCT06171594 ↗ |
| Known as | Curasept ADS310 | “Extraction sockets are filled with 1% chlorhexidine gel (Curasept ADS310, Sager Pharma, Sager Dental Kft.,Budapest, Hungary) before suture (Surgilon 3-0 non-absorbable) placements.” NCT03741894 ↗ |
| Known as | EZ scrub | “EZ scrub vaginal chlorhexidine 4% solution” NCT03925155 ↗ |
| Known as | Hexadyl | “Group II (CHX group): will brush their teeth by Colgate maxfresh ® toothpaste containing sodium fluoride 0.24% in addition to Hexadyl® Chlorhexidine mouthwash for 3 month twice a day.” NCT07814898 ↗ |
| Known as | Hexitol | “Participants in the control group will use a chlorohexidine mouthwash (Hexitol).” NCT07662226 ↗1“0.12% Chlorhexidine Mouthwash ( Hexitol )” NCT07016659 ↗ |
| Known as | Hibiclens | “Chlorhexidine (Hibiclens): once a day for 14 days, rinse body with chlorhexidine.” NCT00560599 ↗2“A preoperative Chlorhexidine gluconate solution 4.0% (i.e Hibiclens)” NCT02510144 ↗ “Chlorhexidine 4% topical soap (Hibiclens)” NCT06397781 ↗ |
| Known as | High Cure | “Local application of High Cure chlorhexidine gel into periodontal pockets following scaling and root planing (SRP).” NCT07801417 ↗ |
| Known as | IrriSept | “0.05% chlorhexidine solution (IrriSept®) commercially prepared in 450 ml bottles will be used to irrigate one breast pocket.” NCT02395614 ↗ |
| Known as | Lifo-Scrub sol 4% | “Chlorhexidine, Lifo-Scrub sol 4%®, 500ml, B. Braun” NCT03962907 ↗ |
| Known as | Oradex | “0.12% chlorhexidine (CHX) (Oradex, Shah Alam, Malaysia) as gold standard” NCT07461155 ↗ |
| Known as | Peridex | “Subjects will also rinse their mouths with 2 ounces of 0.12% chlorhexidine/peridex mouthrinse two times per day.” NCT01568944 ↗ |
| Known as | PerioChip | “PerioChip Plus (Flurbiprofen +Chlorhexidine ), Flurbiprofen Chip, PerioChip (Chlorhexidine ) and Placebo Chip” NCT00425451 ↗ |
| Known as | PerioGard | “Chlorhexidine gluconate 0.12% (PerioGard®)” NCT02695901 ↗ |
| Known as | PerioKIN | “Chlorhexidine (PerioKIN) (0.2%) implantation in dental pockets” NCT02131922 ↗ |
| Known as | Unity antiseptic hand wash (no alcohol) | “commercially available 4% chlorhexidine skin cleanser - Unity antiseptic hand wash (no alcohol)” NCT03348917 ↗ |
| Action | Inhibit | “Chlorhexidine mouth rinse has been considered the most effective agent in inhibiting Streptococcus mutans.” NCT04399161 ↗ |
| Modality | Small molecule | “Chlorhexidine (CHX) digluconate, a cationic biguanide” NCT01580943 ↗ |
| Route | Oral | “daily chlorhexidine oral rinses” NCT00067340 ↗ |