Chlorhexidine
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | CHLORAPREP ONE-STEP | — | 2000-07-14 | fda.gov ↗ |
Trials 154 · started per year
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 05 trials | ||||||
| Phase 0 | NCT07461155 | Jul 2026 → Jul 2027 expected | gingivitis | Ministry of Higher Education, Malaysia | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT03384537 | Feb 2024 → Oct 2026 expected | tooth disorder | Cairo University | Recruiting | No outcome recorded |
| Phase 0 | NCT05024760 | Jul 2022 → Nov 2025 overdue | mucositis, periodontitis, prosthesis-related infectious disease | Madigan Army Medical Center | Recruiting | No outcome recorded |
| Phase 0 | NCT04679558 | Sep 2020 → Jul 2021 | dental caries | Cairo University | Completed | No outcome recorded |
| Phase 0 | NCT02990013 | Dec 2018 → Dec 2019 | toxic dermatosis | University of Miami | Completed | No outcome recorded |
| Phase 11 trial | ||||||
| Phase 1 | NCT00841074 | Jan 2006 → Jul 2011 | pneumonia | University of Louisville | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT04385680 | May 2020 → Mar 2022 | endometritis, skin infection | Zagazig University | Completed | No outcome recorded |
| Phase 219 trials | ||||||
| Phase 2 | NCT07481955 | Mar 2026 → Mar 2027 expected | bacterial vaginosis | Freya Biosciences ApS | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06792812 | Jan → Apr 2025 | chronic gingivitis | Al-Mustansiriyah University | Completed | No outcome recorded |
| Phase 2 | NCT06120140 | Feb 2024 → May 2027 expected | non-small cell lung carcinoma | Janssen Research & Development, LLC | Active not recruiting | No outcome recorded |
| Phase 2 | NCT05505214 | Sep 2023 → Sep 2025 | radiodermatitis | Montefiore Medical Center | Withdrawn | No outcome recorded |
| Phase 2 | NCT06002295 | Sep 2020 → Sep 2021 | neonatal sepsis, omphalitis | Sheikh Zayed Federal Postgraduate Medical Institute | Completed | No outcome recorded |
| Phase 2 | NCT04344236 | Apr → May 2020 | COVID-19 | NYU Langone Health | Withdrawn | No outcome recorded |
| Phase 2 | NCT04453124 | Nov 2019 | chronic ulcer of skin, yaws | Oriol Mitja | Completed | No outcome recorded |
| Phase 2 | NCT03503370 | Jan 2019 → Dec 2022 | ulcer of lower limbs | VA Office of Research and Development | Completed | No outcome recorded |
| Phase 2 | NCT03614429 | Jun → Dec 2018 | — | Cairo University | Unknown | No outcome recorded |
| Phase 2 | NCT03484507 | Jan 2018 → Nov 2022 | Acanthamoeba keratitis | University of California, San Francisco | Completed | No outcome recorded |
| Phase 2 | NCT02678104 | Oct 2016 → Jun 2017 | alveolar periostitis | Riyadh Colleges of Dentistry and Pharmacy | Unknown | No outcome recorded |
| Phase 2 | NCT02788786 | Jun → Nov 2016 | periodontitis | Johns Hopkins Bloomberg School of Public Health | Completed | No outcome recorded |
| Phase 2 | NCT03334461 | Dec 2015 → Mar 2022 | enamel caries, gingivitis | University of Rijeka | Completed | No outcome recorded |
| Phase 2 | NCT02252588 | Sep 2014 → Dec 2019 | chronic obstructive pulmonary disease | University of Minnesota | Completed | No outcome recorded |
| Phase 2 | NCT02396329 | Jun 2014 → Jun 2015 | — | Ain Shams Maternity Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT02077920 | Mar 2014 → Jun 2019 | — | General Hospital of Shenyang Military Region | Completed | No outcome recorded |
| Phase 2 | NCT02132546 | Feb → Oct 2011 | — | dott. Lorenzo Bevilacqua | Completed | No outcome recorded |
| Phase 2 | NCT00425451 | Aug 2008 → Jan 2009 | periodontitis | Dexcel Pharma Technologies Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT00266448 | Jan 2001 → Apr 2004 | — | Heidelberg University | Completed | No outcome recorded |
| Phase 2/35 trials | ||||||
| Phase 2/3 | NCT06900881 | Apr → Sep 2025 overdue | gingivitis | Al-Mustansiriyah University | Recruiting | No outcome recorded |
| Phase 2/3 | NCT03883828 | Jun 2019 → Dec 2021 | radiodermatitis | Montefiore Medical Center | Completed | No outcome recorded |
| Phase 2/3 | NCT03836781 | Apr 2018 → Jun 2019 | chronic periodontitis | Amirhossein Farahmand | Completed | No outcome recorded |
| Phase 2/3 | NCT04399161 | Feb → Dec 2017 | — | Dr. Krupa NC | Completed | No outcome recorded |
| Phase 2/3 | NCT01723501 | Nov 2012 → ? | neonatal sepsis | All India Institute of Medical Sciences | Withdrawn | No outcome recorded |
| Phase 325 trials | ||||||
| Phase 3 | NCT07559877 | Apr 2026 → Jun 2027 expected | nasopharyngeal carcinoma | Jiangxi Provincial Cancer Hospital | Recruiting | No outcome recorded |
| Phase 3 | NCT06732466 | Mar → Apr 2025 | gingivitis, smooth surface dental caries | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT06702878 | Dec 2024 → Apr 2026 | infectious disease | Ondine Biomedical Inc. | Completed | No outcome recorded |
| Phase 3 | NCT06489431 | Dec 2023 → May 2026 overdue | erectile dysfunction, prosthesis-related infectious disease | Rush University Medical Center | Active not recruiting | No outcome recorded |
| Phase 3 | NCT03700788 | May 2023 → Jun 2025 | periodontitis | University of Southern California | Unknown | No outcome recorded |
| Phase 3 | NCT05084378 | Mar 2022 → Aug 2024 | periprosthetic joint infection | Hamilton Health Sciences Corporation | Completed | No outcome recorded |
| Phase 3 | NCT07351370 | Jan → Jul 2022 | periodontal disorder | Dental School | Completed | No outcome recorded |
| Phase 3 | NCT05532241 | Nov 2021 → May 2025 overdue | gingivitis, malposition of teeth with or without hypodontia/oligodontia | University of Rijeka | Active not recruiting | No outcome recorded |
| Phase 3 | NCT04256798 | Nov 2020 → Oct 2025 overdue | pneumonia, skin infection | University of Birmingham | Recruiting | No outcome recorded |
| Phase 3 | NCT03925155 | May 2020 → May 2022 | — | Montefiore Medical Center | Withdrawn | No outcome recorded |
| Phase 3 | NCT03838575 | Mar 2019 → May 2023 | — | University of Birmingham | Unknown | No outcome recorded |
| Phase 3 | NCT03417661 | Jun 2018 → Jun 2019 | — | Gama Healthcare Ltd. | Completed | No outcome recorded |
| Phase 3 | NCT02753387 | May 2016 → Sep 2018 | primary bacterial infectious disease | Rennes University Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02578771 | Oct 2015 → Jan 2016 | — | Zurex Pharma, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT02414581 | Apr 2015 → Aug 2016 | neutropenia | Hospital Regional de Alta Especialidad del Bajio | Completed | No outcome recorded |
| Phase 3 | NCT02208154 | Dec 2013 → Oct 2017 | bacterial infectious disease with sepsis | MJM Bonten | Completed | No outcome recorded |
| Phase 3 | NCT01989416 | Dec 2013 → Jan 2015 | bacterial infectious disease | Mahidol University | Completed | No outcome recorded |
| Phase 3 | NCT01361997 | Jun 2011 → Aug 2012 | infectious disease | University of Guanajuato | Completed | No outcome recorded |
| Phase 3 | NCT01528852 | May 2011 → Sep 2014 | omphalitis | Johns Hopkins Bloomberg School of Public Health | Completed | No outcome recorded |
| Phase 3 | NCT00682006 | Jan 2008 → Sep 2009 | omphalitis | Aga Khan University | Completed | No outcome recorded |
| Phase 3 | NCT00560599 | Apr 2007 → Feb 2012 | methicillin-resistant staphylococcus aureus infectious disease | loren g miller | Completed | No outcome recorded |
| Phase 3 | NCT00136370 | Apr 2004 → Nov 2007 | infectious disease with sepsis, puerperal infection | Centers for Disease Control and Prevention | Unknown | No outcome recorded |
| Phase 3 | NCT00290290 | Sep 2003 → May 2008 | — | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 3 | NCT00067340 | Apr 2003 → Jul 2006 | dental caries | University of Washington | Terminated | No outcome recorded |
| Phase 3 | NCT00004640 | May 1998 → May 2008 | dental caries, periodontal disorder | University of Washington | Completed | No outcome recorded |
| Phase 443 trials | ||||||
| Phase 4 | NCT06397781 | Jan 2031 → Dec 2035 expected | atopic eczema | Boston Children's Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07311343 | Jan → Dec 2026 expected | hemorrhagic disease, pneumonia | Beijing Tiantan Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT07124650 | Sep 2025 → Dec 2026 expected | — | Saint Petersburg State University, Russia | Recruiting | No outcome recorded |
| Phase 4 | NCT06598514 | Dec 2024 → Apr 2026 overdue | urinary tract infection | Oregon Health and Science University | Active not recruiting | No outcome recorded |
| Phase 4 | NCT07048899 | Sep 2024 → Dec 2025 overdue | — | The University of Texas Health Science Center at Tyler | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT07451678 | Jul → Aug 2024 | blepharitis | Instituto de Oftalmología Fundación Conde de Valenciana | Completed | No outcome recorded |
| Phase 4 | NCT04171817 | May 2023 → Sep 2025 | Clostridium difficile colitis, Pseudomonas aeruginosa infectious disease, methicillin-resistant staphylococcus aureus infectious disease | Johns Hopkins Bloomberg School of Public Health | Completed | No outcome recorded |
| Phase 4 | NCT07270952 | Jan → Apr 2023 | gingivitis | Stony Brook University | Completed | No outcome recorded |
| Phase 4 | NCT04337749 | Nov → Dec 2022 | — | Mahidol University | Withdrawn | No outcome recorded |
| Phase 4 | NCT05402995 | Jun 2022 → Aug 2023 | — | Brett D. Crist | Terminated | No outcome recorded |
| Phase 4 | NCT05211622 | Mar → Dec 2022 | stomatitis | University of Palermo | Unknown | No outcome recorded |
| Phase 4 | NCT04027179 | Aug 2020 → Dec 2021 | periodontitis | University of Taubate | Unknown | No outcome recorded |
| Phase 4 | NCT04223076 | Mar → Dec 2019 | periodontitis | University of Oslo | Unknown | No outcome recorded |
| Phase 4 | NCT03757143 | Jan → Sep 2019 | — | Poitiers University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03962907 | Jan 2019 → Mar 2020 | staphylococcus aureus infection | Lindenhofgruppe AG | Completed | No outcome recorded |
| Phase 4 | NCT03560193 | Sep 2018 → May 2022 | — | Poitiers University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03741894 | Sep 2018 → Sep 2020 | alveolar periostitis, impacted teeth, multiple, pulpitis | University of Pecs | Unknown | No outcome recorded |
| Phase 4 | NCT03523962 | Aug 2018 → Mar 2023 | — | University of Maryland, Baltimore | Completed | No outcome recorded |
| Phase 4 | NCT03412734 | May 2018 → Aug 2019 | — | TriHealth Inc. | Terminated | No outcome recorded |
| Phase 4 | NCT02202304 | Sep 2017 → Sep 2019 | dental caries, periodontal disorder | Rosa Moreno Lopez | Withdrawn | No outcome recorded |
| Phase 4 | NCT05178823 | Jun 2017 → Sep 2019 | dental caries, gingival disorder | Semmelweis University | Completed | No outcome recorded |
| Phase 4 | NCT03103204 | Jan → Jul 2017 | morbid obesity, periodontitis | University of Taubate | Completed | No outcome recorded |
| Phase 4 | NCT03940729 | Dec 2016 → Jan 2020 | — | Lund University | Completed | No outcome recorded |
| Phase 4 | NCT02606565 | Jul 2016 → Oct 2020 | infectious disease with sepsis, omphalitis | Makerere University | Completed | No outcome recorded |
| Phase 4 | NCT02695901 | Mar → Dec 2016 | — | Federal University of Santa Maria | Unknown | No outcome recorded |
| Phase 4 | NCT02572791 | Oct 2015 → Nov 2024 | methicillin-resistant staphylococcus aureus infectious disease, skin disease caused by bacterial infection | Washington University School of Medicine | Completed | No outcome recorded |
| Phase 4 | NCT03639363 | Aug 2015 → Apr 2016 | nosocomial infection | University Of Perugia | Completed | No outcome recorded |
| Phase 4 | NCT04868513 | Jan 2015 → Oct 2017 | — | Biochemical and Microbiology Laboratory, Faculty of Dentistry, Autonomous University of San Luis Pot | Completed | No outcome recorded |
| Phase 4 | NCT02279381 | Nov 2014 → Nov 2015 | — | Aga Khan University | Completed | No outcome recorded |
| Phase 4 | NCT04218799 | Aug 2014 → Sep 2015 | — | University of Maryland, Baltimore | Completed | No outcome recorded |
| Phase 4 | NCT02017145 | Feb 2014 → Feb 2015 | — | Sanford Health | Unknown | No outcome recorded |
| Phase 4 | NCT02032394 | Jul 2013 → Feb 2014 | bacteriuria, nosocomial infection, urinary tract infection | Mashhad University of Medical Sciences | Unknown | No outcome recorded |
| Phase 4 | NCT02479347 | Mar 2013 → Sep 2016 | breast neoplasm, skin infection | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | Completed | No outcome recorded |
| Phase 4 | NCT01844141 | Jan → Apr 2013 | nail disorder | Universidad Complutense de Madrid | Unknown | No outcome recorded |
| Phase 4 | NCT01883596 | Oct 2012 → Oct 2016 | — | Sinaloa Pediatric Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT04222699 | Sep 2012 → Nov 2014 | — | VA Office of Research and Development | Completed | No outcome recorded |
| Phase 4 | NCT02124655 | Sep 2012 → Jun 2013 | periodontitis | University of Santiago de Compostela | Completed | No outcome recorded |
| Phase 4 | NCT02215460 | Apr 2012 → Mar 2014 | periodontitis | University of Taubate | Completed | No outcome recorded |
| Phase 4 | NCT01366417 | May → Jun 2011 | — | C. R. Bard | Completed | No outcome recorded |
| Phase 4 | NCT01314703 | Mar → Apr 2011 | — | C. R. Bard | Completed | No outcome recorded |
| Phase 4 | NCT02062047 | Dec 2007 → Mar 2010 | chronic periodontitis, type 2 diabetes mellitus | University of Guarulhos | Completed | No outcome recorded |
| Phase 4 | NCT01213550 | Mar 2006 → Dec 2007 | — | Ege University | Completed | No outcome recorded |
| Phase 4 | NCT00198679 | Mar 2004 → Mar 2005 | skin infection | Johns Hopkins Bloomberg School of Public Health | Completed | No outcome recorded |
| Phase not applicable54 trials | ||||||
| — | NCT07611123 | Apr → May 2026 | — | Biointelligent Technology Systems SL | Completed | No outcome recorded |
| — | NCT07307716 | Feb → Oct 2026 expected | gingivitis, smooth surface dental caries | Riyadh Elm University | Not yet recruiting | No outcome recorded |
| — | NCT07490873 | Jan → Jul 2026 | — | University of Baghdad | Completed | No outcome recorded |
| — | NCT07215156 | Oct 2025 → Apr 2026 overdue | chronic periodontitis | Kafrelsheikh University | Not yet recruiting | No outcome recorded |
| — | NCT07115784 | Jul 2025 → Jan 2026 | gingival overgrowth, tooth hard tissue disease | Khyber Medical University Peshawar | Completed | No outcome recorded |
| — | NCT07031388 | Jul → Sep 2025 | gingival disorder | Ramziyah Hayder Bakr | Completed | No outcome recorded |
| — | NCT07540624 | May 2025 → Jun 2026 overdue | periodontitis | Inonu University | Active not recruiting | No outcome recorded |
| — | NCT07058727 | May → Nov 2025 overdue | — | Cukurova University | Recruiting | No outcome recorded |
| — | NCT07138586 | Jan → Apr 2025 | ulcerative stomatitis | National Research Centre, Egypt | Completed | No outcome recorded |
| — | NCT06625645 | Jan → May 2025 overdue | dental pulp necrosis, periapical periodontitis | Mahy Abdel Raouf Aly Kamar | Not yet recruiting | No outcome recorded |
| — | NCT06875440 | Sep 2024 → Jan 2025 overdue | periodontal disorder | Islamic Azad University, Sanandaj | Enrolling by invitation | No outcome recorded |
| — | NCT06541145 | Aug → Oct 2024 | — | Duke University | Completed | No outcome recorded |
| — | NCT07123792 | Jun 2024 → May 2025 | periodontal disorder | HITEC-Institute of Medical Sciences | Completed | No outcome recorded |
| — | NCT07482007 | Apr 2024 → Jan 2026 | — | Tanta University | Completed | No outcome recorded |
| — | NCT06834711 | Feb → Dec 2024 | chronic apical periodontitis | Cukurova University | Completed | No outcome recorded |
| — | NCT06171594 | Dec 2023 → Jul 2024 | tooth erosion, non-bacterial | University of Portsmouth | Unknown | No outcome recorded |
| — | NCT06077032 | Nov 2023 → Oct 2025 | common wart | Assiut University | Unknown | No outcome recorded |
| — | NCT04781036 | May 2023 → Dec 2024 | infectious disease | Mahidol University | Unknown | No outcome recorded |
| — | NCT05803590 | May → Jul 2023 | gingivitis | Cairo University | Unknown | No outcome recorded |
| — | NCT07570927 | Apr → Nov 2022 | — | Masaryk University | Completed | No outcome recorded |
| — | NCT05548361 | Apr 2022 → Dec 2024 | periodontitis | Cukurova University | Completed | No outcome recorded |
| — | NCT06191497 | Mar 2022 → Oct 2023 | periodontitis | University of Rijeka | Unknown | No outcome recorded |
| — | NCT05846139 | Jan → Nov 2022 | periodontitis | Tuscan Dental Institute | Completed | No outcome recorded |
| — | NCT05122169 | Dec 2021 → Dec 2025 | — | Seoul National University Hospital | Unknown | No outcome recorded |
| — | NCT05016713 | Jun 2021 → Jul 2023 | — | Cairo University | Unknown | No outcome recorded |
| — | NCT05543603 | Apr 2021 → Jan 2022 | COVID-19 | FISABIO Foundation | Completed | No outcome recorded |
| — | NCT04733196 | Oct → Dec 2020 | gingivitis | Plovdiv Medical University | Completed | No outcome recorded |
| — | NCT04707742 | Jun 2020 → Sep 2021 | COVID-19 | FISABIO Foundation | Completed | No outcome recorded |
| — | NCT04403971 | May → Oct 2020 | pneumonia | National Cheng-Kung University Hospital | Completed | No outcome recorded |
| — | NCT04009616 | Mar → Jun 2019 | — | Damascus University | Completed | No outcome recorded |
| — | NCT04074915 | Dec 2018 → Apr 2019 | chronic periodontitis | Institute of Dental Sciences, Bareilly, Uttar Pradesh, India | Completed | No outcome recorded |
| — | NCT03526770 | May → Jul 2018 | tooth hard tissue disease | Dr Meru S | Completed | No outcome recorded |
| — | NCT03510962 | Apr → Jul 2018 | tooth hard tissue disease | Dr Meru S | Completed | No outcome recorded |
| — | NCT03064191 | Sep 2017 → Mar 2018 | tooth disorder | rayan rabie dahab | Unknown | No outcome recorded |
| — | NCT03492827 | Jun 2017 → Jun 2019 | esophageal cancer, gastric cancer | Peking University Third Hospital | Unknown | No outcome recorded |
| — | NCT03442218 | Jun → Aug 2017 | endometritis | Saint Thomas Hospital, Panama | Completed | No outcome recorded |
| — | NCT03009006 | Jan → Oct 2017 | dental pulp necrosis | Cairo University | Unknown | No outcome recorded |
| — | NCT02950246 | Nov 2016 → Jul 2018 | prosthesis-related infectious disease | Hôpital Raymond Poincaré | Unknown | No outcome recorded |
| — | NCT02709785 | Mar 2016 → May 2017 | gingivitis, periodontitis | St. Louis University | Completed | No outcome recorded |
| — | NCT02395614 | Dec 2015 → Dec 2020 | breast cancer | Vanderbilt University Medical Center | Completed | No outcome recorded |
| — | NCT02027324 | Jun 2015 → Feb 2017 | — | Brigham and Women's Hospital | Withdrawn | No outcome recorded |
| — | NCT03393819 | Oct 2014 → Jan 2016 | osteoarthritis, hip, prosthesis-related infectious disease | Lakehead University | Completed | No outcome recorded |
| — | NCT02375178 | Aug → Oct 2014 | periodontal disorder, smooth surface dental caries | Universidade do Vale do Sapucai | Completed | No outcome recorded |
| — | NCT02063867 | Apr 2014 → Feb 2019 | methicillin-resistant staphylococcus aureus infectious disease, nosocomial infection | University of California, Irvine | Completed | No outcome recorded |
| — | NCT02202577 | Mar 2014 → Jul 2016 | — | Case Western Reserve University | Completed | No outcome recorded |
| — | NCT02115776 | Jan 2014 → Apr 2015 | bacterial infectious disease | University of Santiago de Compostela | Completed | No outcome recorded |
| — | NCT02126267 | Jan 2013 → Feb 2014 | chronic periodontitis | Centro Universitario de Lavras | Completed | No outcome recorded |
| — | NCT01886001 | Nov 2012 → May 2013 | — | University of Virginia | Completed | No outcome recorded |
| — | NCT01568944 | Mar 2012 → Sep 2014 | chronic periodontitis | Augusta University | Completed | No outcome recorded |
| — | NCT02131922 | Sep 2009 → Sep 2014 | chronic periodontitis, hypertensive disorder | Jagiellonian University | Unknown | No outcome recorded |
| — | NCT00719329 | Aug 2008 → Sep 2009 | infectious disease | Johns Hopkins Bloomberg School of Public Health | Completed | No outcome recorded |
| — | NCT00247897 | Nov 2005 → Oct 2007 | skin disease caused by bacterial infection | University of British Columbia | Completed | No outcome recorded |
| — | NCT00947518 | Aug 2005 → Feb 2006 | fetal growth restriction, neonatal sepsis | All India Institute of Medical Sciences | Completed | No outcome recorded |
| — | NCT00223002 | Nov 2004 → Jan 2007 | — | University of Saskatchewan | Completed | No outcome recorded |
| Phase not stated1 trial | ||||||
| — | NCT04035161 | Apr → Dec 2019 | — | Becton, Dickinson and Company | Completed | No outcome recorded |
Also used as a comparator or background therapy in 148 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 03 trials | ||||||
| Phase 0 | NCT03957291 Comparator | Aug 2019 → Aug 2022 | — | Assiut University | Unknown | No outcome recorded |
| Phase 0 | NCT03571100 Comparator | May 2018 → May 2019 | age-related macular degeneration, retinal vein occlusion | Mid Atlantic Retina | Unknown | No outcome recorded |
| Phase 0 | NCT03209115 Comparator | Jul → Sep 2017 | — | Cairo University | Unknown | No outcome recorded |
| Phase 111 trials | ||||||
| Phase 1 | NCT07662226 Comparator | Aug → Nov 2026 expected | gingival disorder | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06505759 Comparator | Jul 2024 → Jul 2025 overdue | periodontal disorder | Krishnadevaraya College of Dental Sciences & Hospital | Recruiting | No outcome recorded |
| Phase 1 | NCT06811779 Comparator | Mar → Jun 2024 | acute apical periodontitis | Armed Forces Institute of Dentistry, Pakistan | Completed | No outcome recorded |
| Phase 1 | NCT06775392 Comparator | Jan → Aug 2024 | periodontal disorder | Krishnadevaraya College of Dental Sciences & Hospital | Completed | No outcome recorded |
| Phase 1 | NCT06050863 Comparator | Nov 2023 → Jun 2024 | periodontal disorder | Krishnadevaraya College of Dental Sciences & Hospital | Unknown | No outcome recorded |
| Phase 1 | NCT05546788 Comparator | Oct → Nov 2023 | periodontitis | Assiut University | Unknown | No outcome recorded |
| Phase 1 | NCT06437262 Comparator | Sep 2022 → Jun 2023 | — | University of Santiago de Compostela | Completed | No outcome recorded |
| Phase 1 | NCT05258955 Comparator | Jun → Dec 2020 | — | Liaquat National Hospital & Medical College | Completed | No outcome recorded |
| Phase 1 | NCT03724578 Comparator | Jan 2019 → Feb 2020 | dental caries | Cairo University | Unknown | No outcome recorded |
| Phase 1 | NCT02160587 Comparator | Jul → Oct 2014 | — | Zurex Pharma, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT02160574 Comparator | Jun → Sep 2014 | — | Zurex Pharma, Inc. | Completed | No outcome recorded |
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT07198919 Comparator | May → Oct 2025 overdue | — | Altamash Institute of Dental Medicine | Enrolling by invitation | No outcome recorded |
| Phase 1/2 | NCT04328753 Comparator | Apr → May 2020 | gingivitis | University of Baghdad | Unknown | No outcome recorded |
| Phase 1/2 | NCT01580943 Comparator | Oct 2011 | smooth surface dental caries | University of Porto | Completed | No outcome recorded |
| Phase 212 trials | ||||||
| Phase 2 | NCT05870059 Comparator | Feb → Jul 2022 | chronic periodontitis | Ziauddin University | Completed | No outcome recorded |
| Phase 2 | NCT04584684 Comparator | Dec 2020 → Oct 2021 | COVID-19 | University of North Carolina, Chapel Hill | Terminated | No outcome recorded |
| Phase 2 | NCT05069246 Comparator | Dec 2020 | gingivitis | Ishrat Rahman | Completed | No outcome recorded |
| Phase 2 | NCT03855527 Comparator | Jan 2018 → Jan 2019 | dental caries | Nourhan M.Aly | Completed | No outcome recorded |
| Phase 2 | NCT03155178 Comparator | Dec 2016 → Apr 2017 | — | Solventum US LLC | Completed | No outcome recorded |
| Phase 2 | NCT03174756 Comparator | Jan 2015 → Nov 2016 | — | Universidad El Bosque, Bogotá | Completed | No outcome recorded |
| Phase 2 | NCT02296645 Comparator | Nov 2014 → Jan 2015 | — | Zurex Pharma, Inc. | Completed | No outcome recorded |
| Phase 2 | NCT02221232 Comparator | Aug → Oct 2014 | — | Zurex Pharma, Inc. | Terminated | No outcome recorded |
| Phase 2 | NCT01122862 Comparator | Apr → May 2010 | — | GlaxoSmithKline | Completed | No outcome recorded |
| Phase 2 | NCT01040286 Comparator | Aug 2009 → Jun 2010 | periodontitis | Dexcel Pharma Technologies Ltd. | Completed | No outcome recorded |
| Phase 2 | NCT00845819 Comparator | Feb 2009 → Oct 2014 | chemotherapy-induced oral mucositis | Seoul National University Hospital | Completed | No outcome recorded |
| Phase 2 | NCT00972803 Comparator | May 2008 → May 2009 | gingivitis | Tabriz University | Completed | No outcome recorded |
| Phase 2/37 trials | ||||||
| Phase 2/3 | NCT04575948 Comparator | Dec 2027 → Nov 2028 expected | poisoning | Misr International University | Not yet recruiting | No outcome recorded |
| Phase 2/3 | NCT03684993 Comparator | Dec 2019 → Jan 2020 | smooth surface dental caries | Cairo University | Completed | No outcome recorded |
| Phase 2/3 | NCT03773094 Comparator | Jan → Nov 2019 | smooth surface dental caries | Cairo University | Unknown | No outcome recorded |
| Phase 2/3 | NCT03640507 Comparator | Oct 2018 → May 2019 | — | Columbia University | Completed | No outcome recorded |
| Phase 2/3 | NCT03853200 Comparator | Apr 2017 → Feb 2018 | acute apical periodontitis, tooth disorder | Dow University of Health Sciences | Completed | No outcome recorded |
| Phase 2/3 | NCT02756377 Comparator | May 2014 → Apr 2015 | periodontal disorder | Islamic Azad University, Sanandaj | Completed | No outcome recorded |
| Phase 2/3 | NCT02560870 Comparator | Mar 2014 → Apr 2015 | chronic periodontitis | Islamic Azad University, Sanandaj | Completed | No outcome recorded |
| Phase 330 trials | ||||||
| Phase 3 | NCT07393802 Comparator | Mar → Apr 2026 overdue | — | University of Baghdad | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07401069 Comparator | Feb → Jun 2026 overdue | gingivitis | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07016659 Comparator | Sep 2025 → Sep 2026 expected | gingivitis, senile plaque formation | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07366398 Comparator | Feb → May 2025 | chronic gingivitis | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT06882564 Comparator | Jan → Apr 2025 overdue | chronic gingivitis | Al-Mustansiriyah University | Recruiting | No outcome recorded |
| Phase 3 | NCT06963788 Comparator | Feb → Apr 2024 | — | Can Tho University of Medicine and Pharmacy | Completed | No outcome recorded |
| Phase 3 | NCT05787600 Comparator | Mar → Apr 2023 | chronic gingivitis | University of Baghdad | Completed | No outcome recorded |
| Phase 3 | NCT04438421 Comparator | Jun → Jul 2020 | chronic gingivitis | University of Milan | Unknown | No outcome recorded |
| Phase 3 | NCT04438434 Comparator | Jun → Jul 2020 | impacted teeth, multiple | University of Milan | Unknown | No outcome recorded |
| Phase 3 | NCT04446533 Comparator | Jun → Jul 2020 | chronic gingivitis, periodontitis | University of Milan | Unknown | No outcome recorded |
| Phase 3 | NCT04430998 Comparator | Jun 2020 | periodontal disorder | University of Milan | Unknown | No outcome recorded |
| Phase 3 | NCT06791746 Comparator | Jan 2020 → Dec 2021 | disease related to hematopoietic stem cell transplant, mouth disorder | Zhejiang University | Completed | No outcome recorded |
| Phase 3 | NCT03782103 Comparator | Jan → May 2019 | — | Zurex Pharma, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT04365270 Comparator | Jan 2019 → Jan 2021 | dentin caries, pulpitis | Ain Shams University | Completed | No outcome recorded |
| Phase 3 | NCT03700749 Comparator | Nov 2018 → Jul 2021 | — | University of Birmingham | Unknown | No outcome recorded |
| Phase 3 | NCT03186261 Comparator | Apr → Nov 2018 | dental caries | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT03142607 Comparator | Feb 2017 → Jan 2018 | gingivitis | Aga Khan University | Unknown | No outcome recorded |
| Phase 3 | NCT03282045 Comparator | Oct 2016 → May 2018 | pharyngitis | Bosnalijek D.D | Completed | No outcome recorded |
| Phase 3 | NCT02831816 Comparator | Aug 2016 → Aug 2017 | — | Zurex Pharma, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT02831998 Comparator | Jul 2016 → Apr 2017 | — | Zurex Pharma, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT02545244 Comparator | Feb → Jun 2015 | gingivitis | Sri Hasanamba Dental College and Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02875769 Comparator | Feb → Mar 2015 | chronic periodontitis | University of Guarulhos | Completed | No outcome recorded |
| Phase 3 | NCT02203591 Comparator | Jul 2014 → Mar 2015 | — | 3M | Completed | No outcome recorded |
| Phase 3 | NCT01968356 Comparator | Oct 2013 → Jan 2014 | — | Solventum US LLC | Terminated | No outcome recorded |
| Phase 3 | NCT01968707 Comparator | Oct 2013 → Jun 2014 | — | Solventum US LLC | Completed | No outcome recorded |
| Phase 3 | NCT01750801 Comparator | Feb 2013 → Jul 2014 | gingivitis, periodontitis | Federal University of Minas Gerais | Unknown | No outcome recorded |
| Phase 3 | NCT00608959 Comparator | May → Jun 2008 | infectious disease | Cadence Pharmaceuticals | Completed | No outcome recorded |
| Phase 3 | NCT00597688 Comparator | Nov 2007 → Apr 2009 | — | All India Institute of Medical Sciences | Completed | No outcome recorded |
| Phase 3 | NCT00636480 Comparator | Oct 2007 → Mar 2008 | — | C. R. Bard | Completed | No outcome recorded |
| Phase 3 | NCT00357877 Comparator | Jul 2006 → Aug 2009 | dental caries | Tufts University | Completed | No outcome recorded |
| Phase 426 trials | ||||||
| Phase 4 | NCT06587880 Comparator | Aug 2025 → Dec 2026 expected | alveolar periostitis | University of Jordan | Recruiting | No outcome recorded |
| Phase 4 | NCT06633588 Comparator | May 2025 → Jun 2026 | staphylococcus aureus infection | Swiss Paraplegic Research, Nottwil | Completed | No outcome recorded |
| Phase 4 | NCT06894667 Comparator | Nov 2024 → Sep 2025 overdue | periodontitis | Kuwait University | Active not recruiting | No outcome recorded |
| Phase 4 | NCT06045429 Comparator | May 2024 → Jun 2025 overdue | — | Charles University, Czech Republic | Recruiting | No outcome recorded |
| Phase 4 | NCT04332796 Comparator | Mar → Nov 2022 | — | Mahidol University | Completed | No outcome recorded |
| Phase 4 | NCT04512638 Background | Jan 2021 → Oct 2025 | osteonecrosis of the jaw | Tim Van den Wyngaert | Unknown | No outcome recorded |
| Phase 4 | NCT03489512 Comparator | Oct 2019 → Oct 2020 | infectious disease with sepsis | La Fe Health Research Institute | Withdrawn | No outcome recorded |
| Phase 4 | NCT04376268 Comparator | Jan 2019 → Nov 2023 | impacted teeth, multiple | Yuzuncu Yil University | Unknown | No outcome recorded |
| Phase 4 | NCT04373421 Comparator | Aug 2018 → Mar 2019 | impacted teeth, multiple | Yuzuncu Yil University | Completed | No outcome recorded |
| Phase 4 | NCT02945722 Comparator | Feb 2018 → Oct 2024 | — | University Hospital of Saint-Etienne | Terminated | No outcome recorded |
| Phase 4 | NCT03348917 Comparator | Dec 2017 → Jan 2018 | — | Mundipharma Manufacturing Pte Ltd. | Completed | No outcome recorded |
| Phase 4 | NCT03372122 Comparator | Dec 2017 → Jan 2018 | — | Caroline Scott | Completed | No outcome recorded |
| Phase 4 | NCT03141554 Comparator | May 2017 | — | Mundipharma Manufacturing Pte Ltd. | Completed | No outcome recorded |
| Phase 4 | NCT03140423 Comparator | May 2017 → Nov 2023 | staphylococcus aureus infection | Harvard Pilgrim Health Care | Completed | No outcome recorded |
| Phase 4 | NCT03142828 Comparator | Apr → Jun 2017 | periodontal disorder | Universidad de Murcia | Completed | No outcome recorded |
| Phase 4 | NCT02911766 Comparator | Nov 2016 | gingivitis | University of Oslo | Unknown | No outcome recorded |
| Phase 4 | NCT03633292 Comparator | Jan 2015 → Sep 2017 | ulcerative stomatitis | University of Santiago de Compostela | Completed | No outcome recorded |
| Phase 4 | NCT02267239 Comparator | Oct → Nov 2014 | gingivitis, periodontitis | University of Santiago de Compostela | Unknown | No outcome recorded |
| Phase 4 | NCT02018094 Comparator | Oct 2013 → Mar 2014 | skin infection | Hull University Teaching Hospitals NHS Trust | Completed | No outcome recorded |
| Phase 4 | NCT02922075 Background | Feb → Dec 2013 | alveolar periostitis | São Paulo State University | Completed | No outcome recorded |
| Phase 4 | NCT02466646 Comparator | Dec 2012 → Sep 2014 | periodontitis, aggressive | Marmara University | Completed | No outcome recorded |
| Phase 4 | NCT02150031 Comparator | Dec 2010 → May 2012 | bacterial infectious disease | University of Santiago de Compostela | Completed | No outcome recorded |
| Phase 4 | NCT01115049 Comparator | Feb → Mar 2010 | mucositis | Federico II University | Completed | No outcome recorded |
| Phase 4 | NCT01400308 Comparator | Feb 2010 → Dec 2011 | methicillin-resistant staphylococcus aureus infectious disease | B. Braun Medical SA | Terminated | No outcome recorded |
| Phase 4 | NCT01290978 Comparator | Feb → Mar 2010 | — | Solventum US LLC | Completed | No outcome recorded |
| Phase 4 | NCT02935322 Comparator | Sep 2009 → Dec 2011 | dental caries, periodontal disorder | University of Oslo | Completed | No outcome recorded |
| Phase not applicable56 trials | ||||||
| — | NCT07535229 Comparator | Apr → Sep 2026 expected | gingivitis | Oman Dental College | Enrolling by invitation | No outcome recorded |
| — | NCT07627945 Comparator | Oct 2025 → Jun 2026 | impacted teeth, multiple | MBD MARKETING SDN. BHD. | Completed | No outcome recorded |
| — | NCT07196618 Comparator | Sep 2025 → Feb 2026 overdue | — | Al-Azhar University | Active not recruiting | No outcome recorded |
| — | NCT07088666 Comparator | Aug 2025 → Feb 2026 | gingivitis, smooth surface dental caries | University of Pavia | Completed | No outcome recorded |
| — | NCT07088653 Comparator | Aug 2025 → Feb 2026 | gingivitis, smooth surface dental caries | University of Pavia | Completed | No outcome recorded |
| — | NCT07119840 Comparator | Aug → Nov 2025 overdue | gingivitis, smooth surface dental caries | Khyber Medical University Peshawar | Recruiting | No outcome recorded |
| — | NCT07421323 Comparator | Aug 2025 → Mar 2026 overdue | neonatal sepsis | Alexandria University | Recruiting | No outcome recorded |
| — | NCT07069166 Comparator | Jul 2025 → Jun 2026 overdue | periodontitis, type 2 diabetes mellitus | University of Pavia | Recruiting | No outcome recorded |
| — | NCT07059572 Comparator | May → Oct 2025 | chronic gingivitis | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Completed | No outcome recorded |
| — | NCT06765330 Comparator | May → Aug 2025 overdue | dental caries | Mersin University | Not yet recruiting | No outcome recorded |
| — | NCT07416136 Background | Apr → Aug 2025 | impacted teeth, multiple | Marmara University | Completed | No outcome recorded |
| — | NCT07233733 Background | Jun 2024 → Mar 2025 | periodontitis | Phạm Đình Thiên Khải | Completed | No outcome recorded |
| — | NCT06435832 Comparator | May 2024 | alveolar periostitis | Recep Tayyip Erdogan University | Unknown | No outcome recorded |
| — | NCT06966817 Comparator | May 2024 → Jun 2025 overdue | — | University of Health Sciences | Enrolling by invitation | No outcome recorded |
| — | NCT06703554 Comparator | Jan → May 2024 | dental caries | Cairo University | Completed | No outcome recorded |
| — | NCT07173725 Comparator | Mar 2023 → Oct 2024 | periodontitis | Bezmialem Vakif University | Completed | No outcome recorded |
| — | NCT07500844 Comparator | Feb 2023 → Nov 2025 | periodontal disorder | Research Centre for Medical Genetics, Russian Federation | Completed | No outcome recorded |
| — | NCT06049589 Comparator | Nov 2022 → Dec 2023 | periodontitis | Fundacion Clinica Pardinas | Completed | No outcome recorded |
| — | NCT05916742 Background | Apr 2022 → Dec 2023 | gingival recession | São Paulo State University | Unknown | No outcome recorded |
| — | NCT05422703 Background | Jan → Jun 2022 | temporomandibular joint dysfunction syndrome | Cairo University | Completed | No outcome recorded |
| — | NCT05304338 Comparator | Oct → Nov 2021 | — | Ataturk University | Completed | No outcome recorded |
| — | NCT05733234 Comparator | May 2021 → Mar 2022 | periodontal disorder | Aristotle University Of Thessaloniki | Completed | No outcome recorded |
| — | NCT04566120 Comparator | Jan 2021 → Dec 2022 | smooth surface dental caries | Cairo University | Completed | No outcome recorded |
| — | NCT03844776 Comparator | Oct 2019 → Dec 2020 | infectious disease | Taibah University | Unknown | No outcome recorded |
| — | NCT03915665 Comparator | Apr 2019 → Nov 2021 | mucositis | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | Completed | No outcome recorded |
| — | NCT04032548 Comparator | Feb → Mar 2019 | gingivitis | Mahsa University | Completed | No outcome recorded |
| — | NCT03594513 Background | Jul 2018 → Nov 2019 | gingival recession | São Paulo State University | Unknown | No outcome recorded |
| — | NCT03535896 Background | Jun → Oct 2018 | plantar fasciitis | Aalborg University | Completed | No outcome recorded |
| — | NCT03173053 Comparator | Feb 2018 → Oct 2021 | movement disorder, staphylococcus aureus infection | Radboud University Medical Center | Terminated | No outcome recorded |
| — | NCT03524872 Background | Jan 2018 → Dec 2019 | alveolar periostitis, dental radicular dysplasia | University of Valencia | Unknown | No outcome recorded |
| — | NCT02939092 Comparator | Jan 2018 | gingival disorder | Cairo University | Unknown | No outcome recorded |
| — | NCT04723732 Comparator | Aug 2017 → Aug 2018 | gingivitis, smooth surface dental caries | King Abdulaziz University | Completed | No outcome recorded |
| — | NCT03551561 Comparator | Jun → Nov 2017 | infectious disease | Universidade do Vale do Sapucai | Completed | No outcome recorded |
| — | NCT03166163 Comparator | May → Jun 2017 | gingival disorder | Cairo University | Unknown | No outcome recorded |
| — | NCT03105960 Comparator | Mar → Jun 2017 | gingival disorder | Cairo University | Unknown | No outcome recorded |
| — | NCT03311243 Background | Jan 2016 → Apr 2017 | beta-thalassemia major, chronic periodontitis | King Saud University | Completed | No outcome recorded |
| — | NCT02560155 Comparator | Nov 2015 → Oct 2017 | musculoskeletal system disorder | Lindenhofgruppe AG | Completed | No outcome recorded |
| — | NCT02219776 Background | Sep 2015 → Jun 2021 | infectious disease | McLaren Health Care | Completed | No outcome recorded |
| — | NCT02510144 Comparator | Aug 2015 → Jul 2018 | — | University of Maryland, Baltimore | Completed | No outcome recorded |
| — | NCT02223520 Comparator | Nov 2014 → Oct 2019 | staphylococcus aureus infection | Johns Hopkins University | Completed | No outcome recorded |
| — | NCT00896402 Comparator | Jul 2014 → Jan 2015 | infectious disease | Northwell Health | Withdrawn | No outcome recorded |
| — | NCT02227485 Comparator | Jul → Nov 2014 | gingivitis | Shiraz University of Medical Sciences | Completed | No outcome recorded |
| — | NCT02054676 Background | Feb 2014 → Apr 2016 | — | Lithuanian University of Health Sciences | Unknown | No outcome recorded |
| — | NCT02814279 Background | Feb 2014 → Oct 2015 | gingival recession | São Paulo State University | Completed | No outcome recorded |
| — | NCT02391714 Background | Oct 2013 → Aug 2014 | — | University of New Mexico | Completed | No outcome recorded |
| — | NCT01870583 Comparator | Feb 2013 → Jul 2014 | — | Montefiore Medical Center | Completed | No outcome recorded |
| — | NCT02949583 Comparator | Mar → May 2012 | gingivitis | Universidade Estadual da Paraiba | Completed | No outcome recorded |
| — | NCT01820455 Comparator | Jan 2012 → Jan 2014 | — | University of Tennessee | Completed | No outcome recorded |
| — | NCT01270776 Comparator | Jan 2011 → Jan 2014 | — | Mount Sinai Hospital, Canada | Unknown | No outcome recorded |
| — | NCT01209234 Comparator | Jan 2011 → Jan 2019 | methicillin-resistant staphylococcus aureus infectious disease | University of California, Irvine | Completed | No outcome recorded |
| — | NCT01909999 Background | Mar 2010 → Oct 2012 | incisors, lower central, absence of | Renato Correa Viana Casarin | Completed | No outcome recorded |
| — | NCT00980980 Comparator | Sep 2009 → Sep 2011 | methicillin-resistant staphylococcus aureus infectious disease | Harvard Pilgrim Health Care | Completed | No outcome recorded |
| — | NCT00731783 Comparator | Jul 2008 → Jan 2010 | abscess, furunculosis, methicillin-resistant staphylococcus aureus infectious disease | Washington University School of Medicine | Completed | No outcome recorded |
| — | NCT00513799 Comparator | Mar 2007 → Jun 2009 | abscess, furunculosis, staphylococcus aureus infection | Washington University School of Medicine | Completed | No outcome recorded |
| — | NCT00612469 Comparator | Oct 2005 → Jul 2006 | dental caries | Federal University of Ceará | Completed | No outcome recorded |
| — | NCT00066040 Background | Jan 2001 → Jan 2006 | dental caries | New York University | Completed | No outcome recorded |
Evidence & citations 40 cited values
Every value below carries the sentence it was read from. 314 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | chlorhexidine | “This is a multi-centre, blinded, parallel-group, placebo-controlled randomised clinical trial that tests the effect of four mouthwashes (cetylpyridinium chloride,...” PMID 34937855 ↗ Dec 2021272“Kloroben topical spray containing chlorhexidine gluconate and benzydamine hydrochloride is applied to the surgical site immediately after impacted mandibular third molar...” NCT07416136 ↗ “Previous studies revealed efficacy of topical choices, including benzoyl peroxide gel, clindamycin-benzoyl peroxide gel, glycopyrrolate cream, erythromycin gel, clindamycin...” NCT04332796 ↗ “Participants will be exposed to chlorohexidine based mouthwash. and will be instructed to use 10 ml of 0.12% chlorhexidine based mouthwash 2 times per day for 1 minute; such a...” NCT04566120 ↗ “Postoperative instructions were given, antibiotics were prescribed for 7 days (amoxicillin 500 mg t.i.d), analgesics to relieve from pain (Paracetamol 750 mg) and chlorhexidine...” NCT02922075 ↗ “This study aimed to study the efficacy of chlorhexidine scrub, zinc oxide nanoparticles (ZnO-NPs) socks and the combination of chlorhexidine scrub and ZnO-NPs socks in...” NCT04337749 ↗ “Chlorhexidine digluconate 2 % solution (Cavity Cleanser, Bisco, USA). Each tooth will receive two drops of cavity cleanser with a micro brush, equivalent to a dose of 10 mg of...” NCT03186261 ↗ “The objective of this study was to determine the efficacy of Aloe vera gel at 80% compared to 0.12% Chlorhexidine gel to alleviate the effects derived from any orthodontic treatment” NCT03633292 ↗ “2% aqueous base chlorhexidine (10 ml single dose containers). Use for the preparation of the skin before insertion of the central venous catheters and at each dressing change.” NCT03489512 ↗ “The use of chlorhexidine for vaginal cleansing before a cesarean delivery in patients with rupture of membranes reduced the risk for endometritis and puerperal fever.” PMID 35051671 ↗ Jan 2022 “Both the groups will receive non surgical periodontal therapy (scaling and root planing) with the chlorhexidine containing adjunct in the form of a mouthrinse.” NCT03311243 ↗ “The aim is to evaluate the antimicrobial activity of chlorhexidine and polyhexamethylene biguanide oral antiseptics on the microorganisms of the oral cavity.” NCT02375178 ↗ “Validated decolonization regimen consisting of intranasal 2% mupirocin ointment applied twice daily as well as chlorhexidine wash used daily to the body.” NCT05505214 ↗ “Decolonization involved chlorhexidine mouthwash, baths or showers with chlorhexidine, and nasal mupirocin for 5 days twice per month for 6 months.” PMID 30763195 ↗ Feb 2019 “One press of the pump (one dose) releases 0.14 ml of the solution with 0.28 mg chlorhexidine digluconate and 0.07 mg of lidocaine hydrochloride.” NCT03282045 ↗ “0.12% chlorhexidine gluconate in a base containing water, 11.6% alcohol, glycerin, PEG-40 sorbitan diisostearate, flavor, and sodium saccharin” NCT06703554 ↗ “immediate intensive oral hygiene treatment (chlorhexidine 20 ml, three times a day) combined with antibiotics (ceftazidime 1 g, every 8 hours)” NCT07311343 ↗ “Before isolation, antisepsis of the oral cavity will be performed by rinsing for 1 min with 10 mL chlorhexidine gluconate mouth-wash 0.2 %.” NCT06625645 ↗ “Patients will be prescribed mouth-rinse with chlorhexidine 0.12% twice daily starting 3 days prior to surgery and for 2 weeks afterward” NCT03524872 ↗ “Application of NF-031 solution (methylene blue 0.01% USP (methylthioninium chloride) and 0.25% chlorhexidine gluconate) in the nares” NCT06702878 ↗ “Subjects in the S group will have three applications of chlorhexidine 0.5% in 70% alcohol applied according to standard protocol.” NCT00247897 ↗ “Participants will rinse with 15 mL chlorhexidine gluconate 0.12% mouthwash (Kin Gingival) for 30 seconds twice daily for 7 days.” NCT07490873 ↗ “A Comparison of Chlorhexidine and Green Tea Mouthwash in Patients With Gingivitis and Their Salivary Neutrophil and TAC Levels” NCT06875440 ↗ “Patients will be given chlorhexidine 0,12% mouth rinse at least every 8 hours starting 24 hours after surgery for 14 days.” NCT02054676 ↗ “a preprocedural rinse solution containing 0.05 percent CPC, 0.12 percent chlorhexidine (CHX) or water, or no rinsing” PMID 20354090 ↗ Apr 2010 “Subjects will also rinse their mouths with 2 ounces of 0.12% chlorhexidine/peridex mouthrinse two times per day.” NCT01568944 ↗ “dentin pretreated using chlorhexidine and follow up of patients at 2 weeks, 3months and 6 months” NCT07196618 ↗ “Dental instrument is used in combination with Chlorhexidine to decontaminate the implant surface” NCT05733234 ↗ “using oral antiseptic chlorhexidine mouthwash (Curasept ADS 212 a 200ml 0,12%) twice per day” NCT03334461 ↗ “2% chlorhexidine (Consepsis®, Ultradent) will be applied to the cavity for 20 seconds.” NCT06765330 ↗ “Daily chlorhexidine (CHG) shower or CHG cloth bath for all non-critical care patients.” NCT02063867 ↗ “An intraoral gel containing 0.5% Chlorhexidine (PERIOPLUS+ FORTE, Curaprox, Curaden)” NCT06894667 ↗ “Subjects will then be given Chlorhexidine 0.12%mouthwash, as an active comparator” NCT06792812 ↗ “with Chlorhexidine currently being the most used drug in such preparation” NCT03551561 ↗ “0.12% chlorhexidine (CHX) (Oradex, Shah Alam, Malaysia) as gold standard” NCT07461155 ↗ “application of chlorhexidine to the intra-oral niches within 24 hours” NCT02466646 ↗ “The skin is cleansed with Chlorhexidine alcohol 0.5 % (Medic).” NCT03535896 ↗ “2%(w/v) Chlorhexidine in 70%(v/v) Isopropyl skin preparation” NCT04035161 ↗ “Hexitol®, 0.12% chlorhexidine gluconate; Arab Drug Company” NCT07662226 ↗ “use 0.12% chlorhexidine or povidone iodine mouthwash daily” NCT05422703 ↗ “Chlorhexidine, topical solution, 50ul, daily, for 2 days” NCT04453124 ↗ “using chlorhexidine and fluoride containing mouth wash” NCT03724578 ↗ “continued daily baths with 2% chlorhexidine cloths” NCT03140423 ↗ “a new 0.20% chlorhexidine (CHX) gel and cymenol” NCT06437262 ↗ “15 ml 0,12% Chlorhexidine, one minute rinse” NCT05543603 ↗ “Chlorhexidine 4% topical soap (Hibiclens)” NCT06397781 ↗ “chlorhexidine bath once a day for 5 days” NCT02945722 ↗ “0.12% Chlorhexidine mouthwash” NCT01909999 ↗ “0.12% Chlorhexidine Gluconate” NCT04584684 ↗ “chlorhexidine-gluconate” NCT01844141 ↗ “Drug: Chlorhexidine” NCT03700788 ↗ |
| Known as | Bexident | “Bexident® (0.12% chlorhexidine solution)” NCT01883596 ↗ |
| Known as | Cavity Cleanser | “Chlorhexidine digluconate 2 % solution (Cavity Cleanser, Bisco, USA). Each tooth will receive two drops of cavity cleanser with a micro brush, equivalent to a dose of 10 mg of...” NCT03186261 ↗ |
| Known as | Cervitec | “Cervitec chlorhexidine varnish” NCT00066040 ↗ |
| Known as | CHG | “superiority of chlorhexidine (CHG)-alcohol over povidone iodine (PVI)-alcohol, the two most common alcohol-based antiseptic solutions used worldwide, is controversial.” PMID 31213447 ↗ Jun 20196“0.05% chlorhexidine gluconate (CHG) (Irrisept®) (Irrimax Corp, Lawrenceville, GA, USA), has shown promise as an alternative irrigant” PMID 39434728 ↗ Sep 2024 “Daily chlorhexidine (CHG) shower or CHG cloth bath for all non-critical care patients.” NCT02063867 ↗ “soap-like solution of 4% chlorhexidine (CHG) followed by water rinsing (CHGwr)” PMID 30267930 ↗ Sep 2018 “using chlorhexidine gluconate (CHG) in an alcohol-based solution” NCT03838575 ↗ “2% chlorhexidine (CHG)-70% isopropanol” NCT03757143 ↗ “Chlorhexidine Gluconate (CHG)-alcohol” NCT02202577 ↗ |
| Known as | chloraprep | “Microbial skin flora on abdominal and groin sites in healthy volunteers were microbiologically sampled following randomization to either ZuraGard, a 2% chlorhexidine/70%...” PMID 32131912 ↗ Jun 202019“Chlorhexidine(chloraprep) has been proven to be better than povidone iodine solution for skin preparation before epidural catheter and intravascular device insertion” NCT00896402 ↗ “This trial is to compare the impact of disinfecting the skin with Chloraprep (2%chlorhexidine and 70% isopropyl alcohol) vs. Betadine” NCT00290290 ↗ “Groupe B: (1) 2% (w/v) CHG-70% (v/v) isopropanol (ChloraPrep™, CareFusion); (2) InsyteTM AutoguardTM BC Winged, BD” NCT03757143 ↗ |
| Known as | ChloraPrep Hi-Lite Orange | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01968707 ↗ |
| Known as | ChloraPrep One-Step | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01366417 ↗ |
| Known as | ChloraPrep with Tint (Scrub Teal) | “ChloraPrep® with Tint (Scrub Teal®)” NCT01290978 ↗ |
| Known as | Chlorhexidin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01400308 ↗ |
| Known as | chlorhexidine acetate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00357877 ↗ |
| Known as | Chlorhexidine Diacetate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04365270 ↗ |
| Known as | chlorhexidine digluconate | “Due to the side effects of chlorhexidine digluconate (CHX) mouthrinsing, a spray has been proposed as an alternative method of CHX delivery to the oral cavity.” PMID 16460251 ↗ Feb 20063“Commercial 0.12% chlorhexidine digluconate mouthwash twice daily (each morning and before bedtime during the 21-day study period) after intake of food.” NCT04575948 ↗ “This intervention represents the positive control group of the study and involves the use of a 0.12% chlorhexidine digluconate mouthwash.” NCT07393802 ↗ “Corsodyl® (0.2% chlorhexidine-digluconate; CHX)” NCT05178823 ↗ |
| Known as | Chlorhexidine digluconate 2 % solution | “Chlorhexidine digluconate 2 % solution” NCT03186261 ↗ |
| Known as | Chlorhexidine gel (PERIOPLUS+ FORTE, Curaprox, Curaden) | “Chlorhexidine gel (PERIOPLUS+ FORTE, Curaprox, Curaden)” NCT06894667 ↗ |
| Known as | chlorhexidine gluconate | “Chlorhexidine gluconate(CHX) is a gluconate salt with a broad-spectrum antiseptic action against Gram-Positive, Gram-negative bacteria, aerobes, facultative anaerobes, and...” NCT06077032 ↗16“This intervention uses a commercially available chlorhexidine gluconate 0.12% mouthwash, widely recognized for its strong antimicrobial properties.” NCT07031388 ↗ “Chlorhexidine gluconate solution (commonly 0.12%) used as an antimicrobial oral rinse following standard postoperative instructions.” NCT07611123 ↗ “0.05% chlorhexidine gluconate (CHG) (Irrisept®) (Irrimax Corp, Lawrenceville, GA, USA), has shown promise as an alternative irrigant” PMID 39434728 ↗ Sep 2024 “vaginal scrub with 4% chlorhexidine gluconate and 10% povidone-iodine antiseptic solution immediately prior to cesarean section” NCT03925155 ↗ “with 25ml chlorhexidine gluconate soap, (Lifo-Scrub sol 4 % 500ml, B. Braun)” NCT03962907 ↗ “A preoperative Chlorhexidine gluconate solution 4.0% (i.e Hibiclens)” NCT02510144 ↗ “Chlorhexidine Gluconate 0.12 % Mouthwash + benzydamine hydrochloride” NCT04373421 ↗ “using chlorhexidine gluconate (CHG) in an alcohol-based solution” NCT03838575 ↗ “0.2% mouthwash solution of chlorhexidine gluconate.” NCT04723732 ↗ “Chlorhexidine Gluconate vaginal solution 0.05%” NCT04385680 ↗ “Chlorhexidine Gluconate 0.12 % Mouthwash” NCT07393802 ↗ “Chlorhexidine Gluconate (CHG)-alcohol” NCT02202577 ↗ “chlorhexidine gluconate (CHG) bathing” PMID 37815567 ↗ Oct 2023 “0.12% chlorhexidine gluconate (CHX)” PMID 21085810 ↗ Sep 2010 “Drug: Chlorhexidine gluconate” NCT01213550 ↗ “Drug: Chlorhexidine Gluconate” NCT03142607 ↗ |
| Known as | chlorhexidine-alcohol | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00290290 ↗ |
| Known as | Chlorhexidine/Thymol varnish | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02202304 ↗ |
| Known as | Chlorohexidine | “Participants will be exposed to chlorohexidine based mouthwash. and will be instructed to use 10 ml of 0.12% chlorhexidine based mouthwash 2 times per day for 1 minute; such a...” NCT04566120 ↗2“Patients will be treated with one of two current clinically-used medications, 2% chlorohexidine (intervention) vs. calcium hydroxide (standard-of-care).” NCT03700788 ↗ “Group 2- Chlorohexidine (CHX).” NCT05069246 ↗ |
| Known as | CHX | “The goal of this clinical trial is to evaluate and compare the antiplaque efficacy and patient reported outcome of three commonly used antiseptic mouthwashes - Chlorhexidine...” NCT07490873 ↗27“Chlorhexidine mouthwash is added to the oral hygiene protocol being used beside fluoride-based toothpaste and interdental brushes. CHX mouthwash is used by patients according...” NCT05016713 ↗ “Chlorhexidine gluconate(CHX) is a gluconate salt with a broad-spectrum antiseptic action against Gram-Positive, Gram-negative bacteria, aerobes, facultative anaerobes, and...” NCT06077032 ↗ “Chlorhexidine was developed in 1950 and is the most used anti-plaque agent. However, the long-term usage of chlorhexidine (CHX) is limited by altered taste perception and tooth...” NCT05803590 ↗ “We aimed to assess the effect of umbilical-cord cleansing with 4% chlorhexidine (CHX) solution, with or without handwashing with antiseptic soap, on the incidence of omphalitis...” PMID 22322126 ↗ Feb 2012 “The investigation assessed the clinical effect of a mouthrinse containing chlorhexidine (CHX) and sodium fluoride (NaF) during a 4-day period of non-brushing and a 6-week...” NCT02935322 ↗ “The effects of the resveratrol-based mouthwash will be compared with 0.12% chlorhexidine (CHX) and a placebo mouthwash under standardized conditions without mechanical oral hygiene” NCT07393802 ↗ “The study tests the efficacy of hyaluronic acid (HYL) mouthwash as adjunct to Chlorhexidine (CHX) mouthwash compared to Chlorhexidine mouthwash only in 16 gingivitis patients.” NCT07366398 ↗ “This randomized clinical trial evaluates the efficacy of sodium hypochlorite (NaOCl), chlorhexidine (CHX), and cold saline as hemostatic agents in partial pulpotomy.” NCT07058727 ↗ “Due to the side effects of chlorhexidine digluconate (CHX) mouthrinsing, a spray has been proposed as an alternative method of CHX delivery to the oral cavity.” PMID 16460251 ↗ Feb 2006 “The overall goal is to assess whether 2% Chlorhexidine (CHX) is superior to Calcium Hydroxide in reducing interappointment pain.” NCT03700788 ↗ “Chlorhexidine (CHX) digluconate, a cationic biguanide, is known to be an effective anti-plaque and anti-inflammatory agent” NCT01580943 ↗ “Then, each canal was irrigated with 3 ml of 2% chlorhexidine (CHX) and finally 5 ml of distilled water was used.” NCT06834711 ↗ “Use of chlorhexidine (CHX), a broad-spectrum topical antiseptic with strong residual activity” PMID 26711437 ↗ Dec 2015 “effect of Chlorhexidine (CHX) mouthwash on healthy control and people with dental erosion” NCT06171594 ↗ “0.12% chlorhexidine (CHX) (Oradex, Shah Alam, Malaysia) as gold standard” NCT07461155 ↗ “comparison with 0.2% chlorhexidine gluconate (CHX) mouthwash” NCT07627945 ↗ “Corsodyl® (0.2% chlorhexidine-digluconate; CHX)” NCT05178823 ↗ “a new 0.20% chlorhexidine (CHX) gel and cymenol” NCT06437262 ↗ “chlorhexidine (CHX)-based interventions” NCT04171817 ↗ “0.2% Chlorhexidine (CHX) mouth rinse” NCT07059572 ↗ “0.12% chlorhexidine (CHX) mouthwash” NCT07088653 ↗ “Group 2: Chlorhexidine gel (CHX 2%)” NCT07123792 ↗ “0.12% chlorhexidine gluconate (CHX)” PMID 21085810 ↗ Sep 2010 “Group 2- Chlorohexidine (CHX).” NCT05069246 ↗ “Chlorhexidine mouthrinse (CHX)” PMID 19184351 ↗ May 2009 “3- Arm 3 chlorhexidine (CHX)” NCT07031388 ↗ |
| Known as | clorhexidine | “Clorhexidine Gel (LACER®, Barcelona, Spain) 0.12%, application 2 times / days for 1 month.” NCT03633292 ↗ |
| Known as | Clorhexidine Dental PHB | “Clorhexidine 0,12% (Clorhexidine Dental PHB©) contains clorhexidine (C22H30N10Cl2).” NCT04707742 ↗ |
| Known as | Consepsis | “2% chlorhexidine (Consepsis®, Ultradent) will be applied to the cavity for 20 seconds.” NCT06765330 ↗ |
| Known as | Corsodyl | “Corsodyl® (0.2% chlorhexidine-digluconate; CHX)” NCT05178823 ↗ |
| Known as | Corsodyl Mint | “0.2% CHX (Corsodyl Mint, GlaxoSmithKline, UK)” NCT06171594 ↗ |
| Known as | Curasept ADS310 | “Extraction sockets are filled with 1% chlorhexidine gel (Curasept ADS310, Sager Pharma, Sager Dental Kft.,Budapest, Hungary) before suture (Surgilon 3-0 non-absorbable) placements.” NCT03741894 ↗ |
| Known as | EZ scrub | “EZ scrub vaginal chlorhexidine 4% solution” NCT03925155 ↗ |
| Known as | Hexitol | “Participants in the control group will use a chlorohexidine mouthwash (Hexitol).” NCT07662226 ↗1“0.12% Chlorhexidine Mouthwash ( Hexitol )” NCT07016659 ↗ |
| Known as | Hibiclens | “Chlorhexidine (Hibiclens): once a day for 14 days, rinse body with chlorhexidine.” NCT00560599 ↗2“A preoperative Chlorhexidine gluconate solution 4.0% (i.e Hibiclens)” NCT02510144 ↗ “Chlorhexidine 4% topical soap (Hibiclens)” NCT06397781 ↗ |
| Known as | IrriSept | “0.05% chlorhexidine solution (IrriSept®) commercially prepared in 450 ml bottles will be used to irrigate one breast pocket.” NCT02395614 ↗ |
| Known as | Lifo-Scrub sol 4% | “Chlorhexidine, Lifo-Scrub sol 4%®, 500ml, B. Braun” NCT03962907 ↗ |
| Known as | Oradex | “0.12% chlorhexidine (CHX) (Oradex, Shah Alam, Malaysia) as gold standard” NCT07461155 ↗ |
| Known as | Peridex | “Subjects will also rinse their mouths with 2 ounces of 0.12% chlorhexidine/peridex mouthrinse two times per day.” NCT01568944 ↗ |
| Known as | PerioChip | “PerioChip Plus (Flurbiprofen +Chlorhexidine ), Flurbiprofen Chip, PerioChip (Chlorhexidine ) and Placebo Chip” NCT00425451 ↗ |
| Known as | PerioGard | “Chlorhexidine gluconate 0.12% (PerioGard®)” NCT02695901 ↗ |
| Known as | PerioKIN | “Chlorhexidine (PerioKIN) (0.2%) implantation in dental pockets” NCT02131922 ↗ |
| Known as | Unity antiseptic hand wash (no alcohol) | “commercially available 4% chlorhexidine skin cleanser - Unity antiseptic hand wash (no alcohol)” NCT03348917 ↗ |
| Action | Inhibit | “Chlorhexidine mouth rinse has been considered the most effective agent in inhibiting Streptococcus mutans.” NCT04399161 ↗ |
| Modality | Small molecule | “Chlorhexidine (CHX) digluconate, a cationic biguanide” NCT01580943 ↗ |
| Route | Oral | “daily chlorhexidine oral rinses” NCT00067340 ↗ |