drugset / Trial / NCT03526770

Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Carbonated Drink

NCT03526770

Completed 30 enrolled Dr Meru S
RandomizedCrossoverSingle-blindPrevention

Summary

The diurnal variation in the flow of saliva and hence the composition of saliva is an established fact. Consumption of acidic and sweetened food and beverage is known to reduce the salivary pH and some of them reduce it to critical pH levels and result in structural damage to the hard tissues of the tooth. The purpose of this study is to ascertain the effect of the select commercially available test carbonated drink containing sugar on the salivary pH and assess the buffering capacity of the saliva with or without various intervention measures following the exposure to the test carbonated drink at different time intervals.

Timeline

Start
2018-05-28
Primary completion
2018-07-05
Completion
2018-12-05

Publications

Drugs

EvaluationDrugModalityDoseRoute
Subject Chlorhexidine Small molecule 0.2 % Other