drugset / Trial / NCT03510962

Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Fruit Juice

NCT03510962

Completed 30 enrolled Dr Meru S
RandomizedCrossoverSingle-blindPrevention

Summary

The diurnal variation in the flow of saliva and hence the composition of saliva is an established fact. Consumption of most types of acidic and sweetened foods and beverages are known to reduce the pH of saliva and some of them even reduce it to critical pH levels and result in structural damage to the hard tissues of the tooth. The purpose of this study is to ascertain the effect of the selected commercially available test fruit-juice drink on the salivary pH and assess the buffering capacity of the saliva with or without various intervention measures following the exposure to the test fruit-juice drink at different time intervals.

Timeline

Start
2018-04-25
Primary completion
2018-07-05
Completion
2018-12-05

Publications

Drugs

EvaluationDrugModalityDoseRoute
Subject Chlorhexidine Small molecule 0.2 % Other
Subject Chlorhexidine Small molecule 10 ml Other