drugset / Trial / NCT07351370

Effects of Two Daily CHX Mouthrinses on Plaque, Gingivitis and Staining

NCT07351370

Phase 3 Completed 81 enrolled Dental School
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Τhe aim of this randomized clinical trial was to investigate the efficacy of two daily mouth rinses containing CHX and different combinations of H2O2 and CPC, when used adjunctive to mechanical oral hygiene, and compare them with a placebo mouth rinse. The primary outcomes evaluated were changes in i) bacterial biofilm accumulation, ii) gingival inflammation, and iii) tooth staining. Secondarily, patient's satisfaction and perspective after the use of these formulations was assessed.

Timeline

Start
2022-01-15
Primary completion
2022-07-20
Completion
2022-07-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Cetylpyridinium Small molecule 0.05 % Oral
Subject Chlorhexidine Small molecule 0.05 % Oral
Subject Hydrogen Peroxide Small molecule 0.8 % Oral

Indications