drugset / Trial / NCT07351370
Effects of Two Daily CHX Mouthrinses on Plaque, Gingivitis and Staining
RandomizedParallel-groupQuadruple-blindPrevention
Summary
Τhe aim of this randomized clinical trial was to investigate the efficacy of two daily mouth rinses containing CHX and different combinations of H2O2 and CPC, when used adjunctive to mechanical oral hygiene, and compare them with a placebo mouth rinse. The primary outcomes evaluated were changes in i) bacterial biofilm accumulation, ii) gingival inflammation, and iii) tooth staining. Secondarily, patient's satisfaction and perspective after the use of these formulations was assessed.
Timeline
- Start
- 2022-01-15
- Primary completion
- 2022-07-20
- Completion
- 2022-07-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cetylpyridinium | Small molecule | 0.05 % | Oral |
| Subject | Chlorhexidine | Small molecule | 0.05 % | Oral |
| Subject | Hydrogen Peroxide | Small molecule | 0.8 % | Oral |