drugset / Trial / NCT06397781
Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients
NaSingle-groupOpen-labelTreatment
Summary
Our hypothesis is that S. aureus skin decolonization in atopic dermatitis reduces disease severity and favorably alters the function and gene expression of epidermal and immune skin cells that contribute to disease severity.
Timeline
- Start
- 2031-01-01
- Primary completion
- 2035-12
- Completion
- 2039-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chlorhexidine | Small molecule | 4 % | Topical |
| Subject | Mupirocin | Small molecule | 2 % | Intranasal |
| Subject | Sulfamethoxazole | Small molecule | 800 mg | Oral |
| Subject | Trimethoprim | Small molecule | 5 mg/kg | Oral |
| Subject | Trimethoprim | Small molecule | 6 mg/kg | Oral |
| Subject | Trimethoprim | Small molecule | 160 mg | Oral |