drugset / Trial / NCT03962907

Preoperative Decolonization and Surgical Site Infections in Orthopaedic Surgery - 2 Year Outcome in Prosthetic Surgery

NCT03962907

Phase 4 Completed 1318 enrolled Lindenhofgruppe AG
RandomizedParallel-groupDouble-blindPrevention

Summary

Surgical site infections in orthopaedic surgery are a major problem. Decolonization has been suggested to reduce infection rates. The study was designed as a prospective, controlled, randomized, single-blinded trial to assess the influence of a decolonization procedure in S. aureus and non - S. aureus carriers. In this trial the 2 - year outcome in the subpopulation of prosthetic elective orthopaedic surgery will be evaluated.

Timeline

Start
2019-01-01
Primary completion
2020-03-30
Completion
2020-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Chlorhexidine Small molecule 25 ml Topical
Subject Mupirocin Small molecule 30 mg Intranasal