drugset / Trial / NCT07662226

Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With Gingivitis

NCT07662226

Phase 1 Not yet recruiting 32 enrolled Cairo University
RandomizedParallel-groupSingle-blindTreatment

Summary

This randomized controlled clinical trial aims to compare the taste acceptance and clinical effectiveness of hyaluronic mouthwash and chlorhexidine mouthwash in children with plaque-induced gingivitis. Clinical outcomes will be assessed using gingival and plaque indices, while taste acceptance will be evaluated using a validated hedonic scale. The findings may help identify a mouthwash that is both effective and acceptable to children, thereby improving adherence to oral hygiene practices.

Timeline

Start
2026-08-01
Primary completion
2026-11-30
Completion
2027-05-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine Small molecule 0.12 % Oral
Comparator Chlorhexidine Small molecule 10 ml Oral
Subject Hyaluronic Acid Other / unclassified 10 ml Oral

Indications