Drugs / Hyaluronic Acid
Hyaluronic Acid
also known as
hyaluronan · Gengigel · Durolane · EUFLEXXA · hyruan · Synvisc-One · HA · hyaDENT BG · +54 more
Other / unclassified targets CD44, PGRMC1 via activation
Trials 162 · started per year
today
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 03 trials | ||||||
| Phase 0 | NCT06947161 | Feb → Aug 2025 overdue | pharyngitis | University of Malaya | Recruiting | No outcome recorded |
| Phase 0 | NCT04645303 | Nov 2020 → Apr 2021 | arthropathy | Dubai Health Authority | Unknown | No outcome recorded |
| Phase 0 | NCT03429140 | Apr 2017 → Jun 2019 | — | Cale Jacobs, PhD | Completed | No outcome recorded |
| Phase 19 trials | ||||||
| Phase 1 | NCT07662226 | Aug → Nov 2026 expected | gingival disorder | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT07658118 | Jul → Dec 2026 expected | chronic pain syndrome, interstitial cystitis | Sverdlovsk Regional Clinical Hospital No.1 | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06463132 | Nov 2024 → Nov 2025 | osteoarthritis, knee | Rion Inc. | Unknown | No outcome recorded |
| Phase 1 | NCT05851560 | May → Sep 2023 | goiter, thyroid cancer | National Taiwan University Hospital | Completed | No outcome recorded |
| Phase 1 | NCT06997731 | May 2023 → Jan 2025 | chronic periodontitis | Kafrelsheikh University | Completed | No outcome recorded |
| Phase 1 | NCT05765240 | Feb → Aug 2023 | — | Atlas University | Unknown | No outcome recorded |
| Phase 1 | NCT05006911 | Aug → Sep 2021 | presbyopia | Optall Vision | Unknown | No outcome recorded |
| Phase 1 | NCT03754010 | Aug 2017 → Apr 2018 | periodontitis | Yuzuncu Yil University | Completed | No outcome recorded |
| Phase 1 | NCT03047096 | Feb → Aug 2017 | osteoarthritis | Zhongda Hospital | Unknown | No outcome recorded |
| Phase 1/27 trials | ||||||
| Phase 1/2 | NCT06437054 | Dec 2026 | sensorineural hearing loss disorder, sudden hearing loss disorder | Seoul National University Hospital | Withdrawn | No outcome recorded |
| Phase 1/2 | NCT07581613 | Nov 2026 → Jun 2029 expected | chronic periodontitis | Siddharth Shanbhag | Not yet recruiting | No outcome recorded |
| Phase 1/2 | NCT06694532 | Oct 2023 → Feb 2026 overdue | temporomandibular joint disorder | Basel khaled mohamed | Recruiting | No outcome recorded |
| Phase 1/2 | NCT04766853 | Jul 2021 → Apr 2023 | Meniere disease, drug-induced hearing loss, noise induced hearing loss, sudden hearing loss disorder | Seoul National University Hospital | Completed | No outcome recorded |
| Phase 1/2 | NCT03728244 | Feb → Nov 2019 | gingival recession | Cairo University | Unknown | No outcome recorded |
| Phase 1/2 | NCT02709525 | Jul 2012 → Jul 2015 | periodontal disorder | Federal University of Minas Gerais | Completed | No outcome recorded |
| Phase 1/2 | NCT01442571 | — | articular cartilage disorder | Hadassah Medical Organization | Unknown | No outcome recorded |
| Phase 210 trials | ||||||
| Phase 2 | NCT06098456 | Nov 2023 → May 2024 | papilloma | Centro di Ricerca Clinica Salentino | Completed | No outcome recorded |
| Phase 2 | NCT06937645 | Sep 2023 → May 2025 overdue | infertility disorder | Al-Nahrain University | Recruiting | No outcome recorded |
| Phase 2 | NCT06170346 | Nov 2022 → Jul 2023 | — | Padjadjaran University | Completed | No outcome recorded |
| Phase 2 | NCT03656484 | Jan → Dec 2019 | chronic periodontitis | Concordia Dent Srl | Completed | No outcome recorded |
| Phase 2 | NCT03384095 | Dec 2018 | arthropathy, breast cancer | Erin Newton | Withdrawn | No outcome recorded |
| Phase 2 | NCT04315103 | Aug 2018 → Jan 2019 | osteoarthritis, knee | Kaohsiung Veterans General Hospital. | Completed | No outcome recorded |
| Phase 2 | NCT02832713 | Jun 2017 → Oct 2021 | osteoarthritis, knee | University Hospital, Strasbourg, France | Unknown | No outcome recorded |
| Phase 2 | NCT03114020 | Mar 2017 → Nov 2019 | alpha 1-antitrypsin deficiency, pulmonary emphysema | Gerard Turino | Completed | No outcome recorded |
| Phase 2 | NCT04525066 | Aug 2013 → Aug 2018 | head and neck squamous cell carcinoma, larynx cancer, voice disorders | Ayhman Al Afif | Completed | No outcome recorded |
| Phase 2 | NCT02207608 | Sep 2011 → Aug 2012 | — | University of Rome Tor Vergata | Completed | No outcome recorded |
| Phase 2/35 trials | ||||||
| Phase 2/3 | NCT05450458 | Feb 2023 → Oct 2024 | — | Hospital Regional Tlalnepantla | Completed | No outcome recorded |
| Phase 2/3 | NCT04821804 | Jan → Sep 2020 | gingival recession | Jordan University of Science and Technology | Completed | No outcome recorded |
| Phase 2/3 | NCT03889925 | Mar 2019 → Oct 2022 | osteoarthritis, knee | Andrews Research & Education Foundation | Completed | No outcome recorded |
| Phase 2/3 | NCT03131882 | Oct 2016 → Jun 2017 | trigger thumb | Mahidol University | Unknown | No outcome recorded |
| Phase 2/3 | NCT00591916 | Jan 2006 → Nov 2010 | — | The University of Texas Medical Branch, Galveston | Withdrawn | No outcome recorded |
| Phase 324 trials | ||||||
| Phase 3 | NCT07474714 | Feb → Aug 2026 overdue | carpal tunnel syndrome | Minia University Hospital | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07102225 | May 2025 → Sep 2026 expected | osteoarthritis, knee | Bangladesh Medical University | Active not recruiting | No outcome recorded |
| Phase 3 | NCT06376981 | Sep 2024 → Dec 2026 expected | tendinitis | Centre Hospitalier Departemental Vendee | Recruiting | No outcome recorded |
| Phase 3 | NCT07317596 | Jun 2024 → Jul 2026 overdue | — | Sana'a University | Enrolling by invitation | No outcome recorded |
| Phase 3 | NCT06388070 | May 2024 → Mar 2025 | dry eye syndrome | Huons Co., Ltd. | Completed | No outcome recorded |
| Phase 3 | NCT06290219 | Mar → Sep 2024 | anosmia | Taichung Veterans General Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT06238934 | Mar 2024 → Mar 2025 overdue | osteoarthritis, knee | National Institute of Traumatology and Orthopaedics | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07183436 | Nov 2023 → Jul 2025 | frozen shoulder | Mahidol University | Completed | No outcome recorded |
| Phase 3 | NCT05116306 | Nov 2021 → Dec 2023 | tooth resorption | Ain Shams University | Unknown | No outcome recorded |
| Phase 3 | NCT06770114 | Oct 2021 → May 2022 | gingivitis | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT04504812 | Feb 2021 → Apr 2025 | osteoarthritis, knee | Johns Hopkins University | Completed | No outcome recorded |
| Phase 3 | NCT04438434 | Jun → Jul 2020 | impacted teeth, multiple | University of Milan | Unknown | No outcome recorded |
| Phase 3 | NCT04265001 | Nov 2019 → Jan 2020 | aphthous stomatitis | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT03870646 | Apr 2019 → Oct 2020 | critical illness polyneuropathy, tracheal disorder | Hospital Universitario Virgen de la Arrixaca | Unknown | No outcome recorded |
| Phase 3 | NCT03390036 | Dec 2017 → Jul 2018 | osteoarthritis, knee | Anika Therapeutics, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT04972383 | Nov 2017 → Oct 2019 | osteoarthritis, knee | Kaohsiung Medical University Chung-Ho Memorial Hospital | Completed | No outcome recorded |
| Phase 3 | NCT03191903 | May 2017 → Apr 2018 | osteoarthritis, knee | Anika Therapeutics, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT03459833 | Aug 2016 → Mar 2018 | premature ejaculation | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT02790177 | Jun 2016 → May 2017 | — | Services Institute of Medical Sciences, Pakistan | Unknown | No outcome recorded |
| Phase 3 | NCT02412735 | Mar 2015 → May 2020 | intervertebral disk degenerative disorder | Mesoblast, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT02381652 | Feb → Apr 2015 | osteoarthritis, knee | Anika Therapeutics, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT02248376 | Nov 2014 → Sep 2018 | adhesions of uterus | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 3 | NCT01079455 | May 2010 → Jul 2012 | osteoarthritis, hip | University Hospital Pellenberg | Unknown | No outcome recorded |
| Phase 3 | NCT00436969 | Dec 2006 → Feb 2010 | osteoarthritis | DePuy Mitek | Completed | No outcome recorded |
| Phase 439 trials | ||||||
| Phase 4 | NCT07504250 | Apr 2026 → Oct 2027 expected | dacryocystitis | All India Institute of Medical Sciences, Bhubaneswar | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07376148 | Nov 2025 → Feb 2026 overdue | skin disorder | Instituto de Oftalmología Fundación Conde de Valenciana | Recruiting | No outcome recorded |
| Phase 4 | NCT07102186 | Jul → Oct 2025 overdue | acne | Badr University | Recruiting | No outcome recorded |
| Phase 4 | NCT07042581 | Jun 2025 → Jun 2029 expected | breast carcinoma in situ, hormone receptor-positive breast cancer | Memorial Sloan Kettering Cancer Center | Recruiting | No outcome recorded |
| Phase 4 | NCT06878599 | May 2025 → Oct 2027 expected | sudden sensorineural hearing loss | Assiut University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06935877 | Apr 2025 → Jun 2026 overdue | bursitis | Shin Kong Wu Ho-Su Memorial Hospital | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06031493 | Jan → Feb 2025 | cervical cancer, sexual disorder | Hospital Clinic of Barcelona | Unknown | No outcome recorded |
| Phase 4 | NCT06694857 | Oct 2024 → Nov 2025 | — | University of Pennsylvania | Completed | No outcome recorded |
| Phase 4 | NCT05446402 | Jun 2022 → May 2023 | acne | Northwestern University | Completed | No outcome recorded |
| Phase 4 | NCT05834517 | May → Dec 2022 | periodontitis | Ehab Haider Hassan El-emam | Completed | No outcome recorded |
| Phase 4 | NCT05818007 | Apr 2022 → Mar 2023 | chemotherapy-induced oral mucositis | Yuzuncu Yil University | Completed | No outcome recorded |
| Phase 4 | NCT05039723 | Sep 2021 → Mar 2022 | — | Main Line Center for Laser Surgery | Completed | No outcome recorded |
| Phase 4 | NCT05768243 | Mar 2021 → Jul 2022 | chronic periodontitis | Beirut Arab University | Completed | No outcome recorded |
| Phase 4 | NCT04586361 | Oct 2020 → Sep 2021 | — | Kaohsiung Veterans General Hospital. | Unknown | No outcome recorded |
| Phase 4 | NCT04274244 | Mar 2020 → Sep 2024 | chronic periodontitis | University of Valencia | Completed | No outcome recorded |
| Phase 4 | NCT04692558 | Jan 2020 → Oct 2021 | gingival recession | Krishnadevaraya College of Dental Sciences & Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT04165902 | Nov 2019 → Jul 2020 | osteoarthritis, knee | Taipei Medical University | Unknown | No outcome recorded |
| Phase 4 | NCT03691467 | Sep 2019 → Jan 2021 | — | Ibrahim Samy Kalboush | Completed | No outcome recorded |
| Phase 4 | NCT04675385 | Jun → Sep 2019 | chronic periodontitis | University of Medicine and Pharmacy at Ho Chi Minh City | Completed | No outcome recorded |
| Phase 4 | NCT03692026 | Oct 2018 → Feb 2020 | — | Cairo University | Unknown | No outcome recorded |
| Phase 4 | NCT03186755 | Jun 2017 → Dec 2024 | vernal conjunctivitis | Michael Marchand, MD | Unknown | No outcome recorded |
| Phase 4 | NCT03077009 | Mar 2017 → Mar 2020 | paratenonitis with tendinosis, tendinosis | Fortius Clinic | Unknown | No outcome recorded |
| Phase 4 | NCT03311906 | Feb → Aug 2017 | periodontitis | Riyadh Colleges of Dentistry and Pharmacy | Completed | No outcome recorded |
| Phase 4 | NCT03211650 | Oct 2016 → Nov 2018 | osteoarthritis, knee | University of Milan | Completed | No outcome recorded |
| Phase 4 | NCT03110679 | May → Nov 2016 | osteoarthritis, knee | Rizzoli Orthopaedic Institute | Completed | No outcome recorded |
| Phase 4 | NCT03825133 | Apr 2016 → Nov 2017 | osteoarthritis, knee | Clinical Center of Vojvodina | Completed | No outcome recorded |
| Phase 4 | NCT02034890 | Jul 2015 → Mar 2017 | urinary tract infection | Rabin Medical Center | Withdrawn | No outcome recorded |
| Phase 4 | NCT03157193 | Sep 2014 → Jan 2016 | periodontitis | University of Granada | Completed | No outcome recorded |
| Phase 4 | NCT02086474 | May 2014 → Aug 2017 | osteoarthritis, hip | Laval University | Completed | No outcome recorded |
| Phase 4 | NCT02366676 | Jan 2014 → Jan 2018 | cystitis | Samsung Medical Center | Completed | No outcome recorded |
| Phase 4 | NCT02534415 | Aug 2013 → Jul 2015 | — | Marmara University | Completed | No outcome recorded |
| Phase 4 | NCT01895959 | Aug 2013 → Nov 2016 | osteoarthritis, knee | University of California, San Francisco | Completed | No outcome recorded |
| Phase 4 | NCT01824485 | Mar 2013 → Mar 2014 | osteoarthritis | University of Sao Paulo General Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02629380 | Dec 2012 → May 2016 | — | Rizzoli Orthopaedic Institute | Completed | No outcome recorded |
| Phase 4 | NCT02630407 | Dec 2012 → Mar 2016 | — | Rizzoli Orthopaedic Institute | Completed | No outcome recorded |
| Phase 4 | NCT01524913 | Jan 2012 → Dec 2015 | temporomandibular joint dysfunction syndrome | Emory University | Completed | No outcome recorded |
| Phase 4 | NCT01387620 | Jun 2009 → Feb 2010 | corneal edema | University of Sao Paulo | Completed | No outcome recorded |
| Phase 4 | NCT00607685 | Feb 2008 → Jan 2010 | glaucoma | Singapore National Eye Centre | Completed | No outcome recorded |
| Phase 4 | NCT00731289 | Jul 2003 → Dec 2005 | osteoarthritis | Philipps University Marburg | Completed | No outcome recorded |
| Phase not applicable65 trials | ||||||
| — | NCT07666347 | Jun → Dec 2026 expected | osteoarthritis, knee | Tanta University | Recruiting | No outcome recorded |
| — | NCT07598253 | Jun → Dec 2026 expected | temporomandibular joint dysfunction syndrome | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT07548203 | Apr → Sep 2026 expected | — | Ain Shams University | Recruiting | No outcome recorded |
| — | NCT07305519 | Apr 2026 → Apr 2027 expected | — | University of Roma La Sapienza | Recruiting | No outcome recorded |
| — | NCT07367087 | Feb → Aug 2026 overdue | — | Nishtar Medical University | Not yet recruiting | No outcome recorded |
| — | NCT07317856 | Jan → Sep 2026 expected | — | University of Baghdad | Not yet recruiting | No outcome recorded |
| — | NCT07236632 | Dec 2025 → Dec 2026 expected | premature ejaculation | Benha University | Not yet recruiting | No outcome recorded |
| — | NCT07205640 | Dec 2025 overdue | dental caries | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT07495072 | Nov 2025 → Dec 2026 expected | cystitis, urinary bladder neoplasm | BLAD-HYA Group | Recruiting | No outcome recorded |
| — | NCT07121439 | Sep → Nov 2025 overdue | hyperpigmentation of the skin | Indonesia University | Not yet recruiting | No outcome recorded |
| — | NCT07031895 | Sep 2025 → Apr 2026 overdue | — | TC Erciyes University | Not yet recruiting | No outcome recorded |
| — | NCT07683351 | Aug 2025 → Aug 2026 overdue | gingival recession | Suez Canal University | Recruiting | No outcome recorded |
| — | NCT07081230 | Jul → Oct 2025 overdue | periodontitis | husain abduljalil alam | Recruiting | No outcome recorded |
| — | NCT07031388 | Jul → Sep 2025 | gingival disorder | Ramziyah Hayder Bakr | Completed | No outcome recorded |
| — | NCT07643402 | Jul → Nov 2025 | temporomandibular joint dysfunction syndrome | Mansoura University | Completed | No outcome recorded |
| — | NCT07291583 | Jul 2025 → Jan 2026 overdue | gingival recession | University of Health Sciences | Active not recruiting | No outcome recorded |
| — | NCT06522438 | Jun 2025 → Dec 2027 expected | periodontitis | Queen Mary University of London | Recruiting | No outcome recorded |
| — | NCT06324474 | Apr → Dec 2025 overdue | periodontitis | Sana'a University | Not yet recruiting | No outcome recorded |
| — | NCT06852105 | Feb 2025 → May 2026 overdue | dry eye syndrome | He Eye Hospital | Not yet recruiting | No outcome recorded |
| — | NCT07570095 | Feb → Mar 2025 | frozen shoulder | Tri-Service General Hospital (TSGH) | Completed | No outcome recorded |
| — | NCT06839313 | Feb → Aug 2025 | aphthous stomatitis | Batman University | Completed | No outcome recorded |
| — | NCT07510295 | Jan → Jul 2025 | skin atrophy | Ngô Anh Tuấn | Completed | No outcome recorded |
| — | NCT07479693 | Jan → Aug 2025 | hydrarthrosis, temporomandibular joint disorder | Ondokuz Mayıs University | Completed | No outcome recorded |
| — | NCT06309719 | Oct 2024 → Dec 2026 expected | periodontitis | Queen Mary University of London | Recruiting | No outcome recorded |
| — | NCT06446843 | Sep 2024 → Mar 2025 | temporomandibular joint disorder | Cairo University | Completed | No outcome recorded |
| — | NCT06492785 | Sep 2024 → Dec 2025 overdue | infertility disorder | Northwest Women's and Children's Hospital, Xi'an, Shaanxi | Recruiting | No outcome recorded |
| — | NCT06777303 | Jun 2024 → Aug 2025 overdue | periodontitis | Mansoura University | Active not recruiting | No outcome recorded |
| — | NCT06161064 | Dec 2023 → Dec 2024 | — | Sohag University | Unknown | No outcome recorded |
| — | NCT06033989 | Oct 2023 → Aug 2024 | bone resorption disease, tooth agenesis | Cairo University | Unknown | No outcome recorded |
| — | NCT06710782 | Aug 2023 → Jul 2024 | chronic pain syndrome, osteoarthritis, knee | Tanta University | Completed | No outcome recorded |
| — | NCT05983081 | Aug 2023 → Aug 2024 | frozen shoulder | Tri-Service General Hospital (TSGH) | Completed | No outcome recorded |
| — | NCT05855070 | May 2023 → May 2024 | Peyronie disease | Benha University | Unknown | No outcome recorded |
| — | NCT06867055 | May 2023 → Aug 2025 | gingival recession | SEVAL CEYLAN ŞEN | Completed | No outcome recorded |
| — | NCT06144814 | Apr → Sep 2023 | postmenopausal atrophic vaginitis | Koru Health Groups | Completed | No outcome recorded |
| — | NCT05543434 | Dec 2022 → Mar 2023 | periodontal disorder | Cairo University | Unknown | No outcome recorded |
| — | NCT05408065 | Nov 2022 → Sep 2026 expected | osteoarthritis | University of Montreal Hospital Centre (CHUM) | Recruiting | No outcome recorded |
| — | NCT06451406 | Oct 2022 → Jun 2023 | — | New Valley University | Completed | No outcome recorded |
| — | NCT07089446 | Sep 2022 → May 2025 | osteoarthritis, knee | University of Karachi | Completed | No outcome recorded |
| — | NCT05953896 | Jan → Jul 2022 | mouth disorder | Aya Elleithy | Completed | No outcome recorded |
| — | NCT02459392 | Dec 2021 | lumbar spinal stenosis | EPC Education s.r.o. | Completed | No outcome recorded |
| — | NCT04544475 | Sep 2021 → Oct 2022 | — | NYU Langone Health | Completed | No outcome recorded |
| — | NCT04975373 | Jun 2021 → Jul 2022 | adhesions of uterus | Barzilai Medical Center | Unknown | No outcome recorded |
| — | NCT05776290 | Feb 2021 → Mar 2022 | — | Damascus University | Completed | No outcome recorded |
| — | NCT04222140 | Aug 2020 → Aug 2021 | osteoarthritis, knee | Affinity Health Research Institute | Unknown | No outcome recorded |
| — | NCT07689695 | Jun 2020 → Jul 2021 | — | Yuzuncu Yil University | Completed | No outcome recorded |
| — | NCT04443166 | Jun 2020 → Jun 2021 | osteoarthritis, knee | Taipei Medical University WanFang Hospital | Unknown | No outcome recorded |
| — | NCT06936462 | Jan 2020 → Jan 2024 | dry eye syndrome | Hallym University Kangnam Sacred Heart Hospital | Completed | No outcome recorded |
| — | NCT03920553 | Jan → Mar 2019 | mouth disorder | Gazi University | Completed | No outcome recorded |
| — | NCT03677895 | Oct 2018 → Mar 2019 | shoulder impingement syndrome | Taipei Veterans General Hospital, Taiwan | Unknown | No outcome recorded |
| — | NCT04395417 | May → Sep 2018 | epicondylitis | Hacettepe University | Completed | No outcome recorded |
| — | NCT03617315 | Oct 2017 → Feb 2018 | dry eye syndrome | University of Seville | Completed | No outcome recorded |
| — | NCT03463499 | Sep 2017 → Sep 2019 | interstitial cystitis | Samsung Medical Center | Completed | No outcome recorded |
| — | NCT03089723 | Mar 2017 → Mar 2018 | metabolic disease | University of Sao Paulo General Hospital | Unknown | No outcome recorded |
| — | NCT06900907 | Mar → Aug 2017 | impacted teeth, multiple | Batman University | Completed | No outcome recorded |
| — | NCT02708706 | Mar 2016 → Dec 2020 | frozen shoulder | Taipei Veterans General Hospital, Taiwan | Completed | No outcome recorded |
| — | NCT04702334 | Jan 2016 → Nov 2018 | periodontitis | University of Roma La Sapienza | Completed | No outcome recorded |
| — | NCT02476903 | Jun 2015 → Jun 2017 | osteoarthritis | Rothman Institute Orthopaedics | Unknown | No outcome recorded |
| — | NCT02465853 | Jan 2015 → Jul 2017 | arthropathy, rotator cuff syndrome, stroke disorder | Chang Gung Memorial Hospital | Completed | No outcome recorded |
| — | NCT02330822 | Dec 2014 → Aug 2015 | — | Damascus University | Completed | No outcome recorded |
| — | NCT02536807 | Aug 2014 → May 2016 | — | Malmö University | Completed | No outcome recorded |
| — | NCT02702206 | Aug 2014 → Oct 2016 | bursitis | Shin Kong Wu Ho-Su Memorial Hospital | Completed | No outcome recorded |
| — | NCT02170857 | Jun 2014 → Feb 2016 | chronic periodontitis | Damascus University | Completed | No outcome recorded |
| — | NCT02755376 | Jan 2014 → Apr 2016 | — | Samsung Medical Center | Completed | No outcome recorded |
| — | NCT01813565 | Mar 2013 → Dec 2016 | interstitial cystitis | Asan Medical Center | Terminated | No outcome recorded |
| — | NCT01950793 | Nov 2012 → May 2014 | — | Taipei Veterans General Hospital, Taiwan | Completed | No outcome recorded |
Also used as a comparator or background therapy in 115 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 06 trials | ||||||
| Phase 0 | NCT07169357 Comparator | Nov 2025 → Feb 2026 overdue | gingival hypertrophy | Beirut Arab University | Enrolling by invitation | No outcome recorded |
| Phase 0 | NCT06797960 Comparator | Feb → Sep 2025 overdue | osteoarthritis, knee | Fayoum University | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT05034965 Comparator | Oct 2021 → Oct 2022 | — | Alexandria University | Unknown | No outcome recorded |
| Phase 0 | NCT03800810 Background | May 2015 → May 2019 | osteoarthritis, knee | Indonesia University | Unknown | No outcome recorded |
| Phase 0 | NCT04326985 Comparator | Jan 2015 → Jan 2019 | osteoarthritis, knee | Chinese University of Hong Kong | Completed | No outcome recorded |
| Phase 0 | NCT01464528 Comparator | Nov 2011 → Mar 2012 | adhesions of uterus | Hadassah Medical Organization | Unknown | No outcome recorded |
| Phase 15 trials | ||||||
| Phase 1 | NCT04893174 Background | Sep 2022 → Sep 2024 | osteoarthritis, knee | Meridigen Biotech Co., Ltd. | Unknown | No outcome recorded |
| Phase 1 | NCT05001243 Comparator | Aug 2021 | presbyopia | Optall Vision | Unknown | No outcome recorded |
| Phase 1 | NCT02698813 Comparator | Dec 2016 → Dec 2018 | — | South China Research Center for Stem Cell and Regenerative Medicine | Unknown | No outcome recorded |
| Phase 1 | NCT02034786 Background | Mar 2015 → May 2016 | lipodystrophy | Cryopraxis Criobiologia Ltda. | Unknown | No outcome recorded |
| Phase 1 | NCT03548662 Comparator | Mar 2014 → Feb 2018 | rotator cuff syndrome | Taipei Veterans General Hospital, Taiwan | Completed | No outcome recorded |
| Phase 1/216 trials | ||||||
| Phase 1/2 | NCT07012525 Comparator | Sep 2025 → Dec 2026 expected | — | Dar Al Uloom University | Not yet recruiting | No outcome recorded |
| Phase 1/2 | NCT07437885 Comparator | Sep 2024 → Jul 2025 | gingival recession | Ordu University | Completed | No outcome recorded |
| Phase 1/2 | NCT06469216 Comparator | Apr → Dec 2024 | enterocolitis, radiation proctitis | Assiut University | Completed | No outcome recorded |
| Phase 1/2 | NCT06572904 Background | Feb → Oct 2024 overdue | temporomandibular joint disorder | Mansoura University | Active not recruiting | No outcome recorded |
| Phase 1/2 | NCT06842511 Comparator | Apr 2023 → May 2024 | periodontitis | Ordu University | Completed | No outcome recorded |
| Phase 1/2 | NCT05742399 Comparator | Dec 2022 → Sep 2023 | eye adnexa disorder, hyperpigmentation of eyelid | Alexandria University | Completed | No outcome recorded |
| Phase 1/2 | NCT05081921 Comparator | Jan 2022 → Feb 2024 | osteoarthritis, knee | Jagiellonian University | Completed | No outcome recorded |
| Phase 1/2 | NCT06544447 Background | Jun 2021 → Oct 2024 overdue | dry eye syndrome | Beijing Tongren Hospital | Recruiting | No outcome recorded |
| Phase 1/2 | NCT06680856 Background | Feb 2021 → Oct 2024 | ulcer of lower limbs | Ospedale Policlinico San Martino | Completed | No outcome recorded |
| Phase 1/2 | NCT04453111 Background | Jan 2020 → Aug 2021 | osteoarthritis, knee | Institute of Cell Therapy | Unknown | No outcome recorded |
| Phase 1/2 | NCT02967874 Comparator | Mar 2016 → Jun 2019 | osteoarthritis, knee | Russian Academy of Medical Sciences | Completed | No outcome recorded |
| Phase 1/2 | NCT02580695 Comparator | Dec 2015 → Jan 2017 | osteoarthritis, knee | Francisco Espinoza, MD | Completed | No outcome recorded |
| Phase 1/2 | NCT02123368 Comparator | May 2012 → Nov 2014 | osteoarthritis | Clinica Universidad de Navarra, Universidad de Navarra | Completed | No outcome recorded |
| Phase 1/2 | NCT01586312 Comparator | Apr 2012 → Dec 2013 | osteoarthritis, knee | Red de Terapia Celular | Completed | No outcome recorded |
| Phase 1/2 | NCT01088191 Comparator | Mar 2009 → Nov 2013 | osteoarthritis | Mesoblast, Inc. | Completed | No outcome recorded |
| Phase 1/2 | NCT00225095 Background | Sep 2005 → Apr 2008 | — | Mesoblast, Ltd. | Completed | No outcome recorded |
| Phase 216 trials | ||||||
| Phase 2 | NCT05909072 Comparator | Jun → Nov 2023 | hyperpigmentation of the skin | Zagazig University | Unknown | No outcome recorded |
| Phase 2 | NCT05027581 Comparator | Oct 2021 → Dec 2023 | osteoarthritis, knee | Taiwan Bio Therapeutics Inc. | Completed | No outcome recorded |
| Phase 2 | NCT04673643 Background | Jul 2021 → Oct 2024 overdue | dry eye syndrome | Beijing Tongren Hospital | Recruiting | No outcome recorded |
| Phase 2 | NCT04520945 Comparator | Oct 2020 → Sep 2021 | osteoarthritis, knee | Meluha Life Sciences SDN BHD | Unknown | No outcome recorded |
| Phase 2 | NCT03491761 Comparator | Jun 2018 → Dec 2025 overdue | osteoarthritis, knee | Endeavor Health | Recruiting | No outcome recorded |
| Phase 2 | NCT03871218 Comparator | Apr 2017 → Apr 2018 | gingival recession | Gazi University | Completed | No outcome recorded |
| Phase 2 | NCT03101163 Background | Dec 2015 → Jul 2022 | articular cartilage disorder | KLSMC Stem Cells, Inc. | Completed | No outcome recorded |
| Phase 2 | NCT04198467 Comparator | Oct 2014 → Apr 2016 | osteoarthritis, knee | Dr. Himanshu Bansal Foundation | Completed | No outcome recorded |
| Phase 2 | NCT01588925 Comparator | Nov 2011 → Feb 2013 | hearing loss disorder | University of Sao Paulo General Hospital | Completed | No outcome recorded |
| Phase 2 | NCT01453738 Background | Nov 2011 → Nov 2014 | osteoarthritis, knee | Stempeutics Research Pvt Ltd | Completed | No outcome recorded |
| Phase 2 | NCT01448434 Background | Sep 2011 → Sep 2013 | osteoarthritis, knee | Stempeutics Research Pvt Ltd | Completed | No outcome recorded |
| Phase 2 | NCT01459640 Comparator | Mar 2011 → Mar 2014 | osteoarthritis | National University of Malaysia | Unknown | No outcome recorded |
| Phase 2 | NCT00993707 Comparator | Nov 2010 → Mar 2013 | chronic obstructive pulmonary disease | Turino, Gerard, M.D. | Completed | No outcome recorded |
| Phase 2 | NCT02958761 Comparator | Aug 2010 → Jan 2014 | osteoarthritis, knee | Fondazione IRCCS Policlinico San Matteo di Pavia | Completed | No outcome recorded |
| Phase 2 | NCT01076673 Comparator | Oct 2009 → May 2012 | articular cartilage disorder | Kuala Lumpur Sports Medicine Centre | Completed | No outcome recorded |
| Phase 2 | NCT01066026 Background | Jul 2009 → Jan 2010 | — | Hexsel Dermatology Clinic | Completed | No outcome recorded |
| Phase 2/36 trials | ||||||
| Phase 2/3 | NCT07352540 Comparator | Jan → Aug 2026 overdue | osteoarthritis, knee | University of Erlangen-Nürnberg Medical School | Active not recruiting | No outcome recorded |
| Phase 2/3 | NCT06517667 Comparator | Nov 2023 → Feb 2024 | dry eye syndrome | University of Seville | Completed | No outcome recorded |
| Phase 2/3 | NCT06478134 Comparator | Jul 2023 → Jan 2024 | dry eye syndrome | University of Seville | Completed | No outcome recorded |
| Phase 2/3 | NCT05076526 Comparator | Nov 2021 → Nov 2022 | osteoarthritis, knee | Singapore General Hospital | Unknown | No outcome recorded |
| Phase 2/3 | NCT01270412 Comparator | Sep 2011 → Dec 2012 | osteoarthritis, knee | Meir Medical Center | Unknown | No outcome recorded |
| Phase 2/3 | NCT00728611 Comparator | Jan 2008 → Feb 2009 | osteoarthritis, knee | Meir Medical Center | Completed | No outcome recorded |
| Phase 314 trials | ||||||
| Phase 3 | NCT06775314 Comparator | Mar → May 2025 overdue | acne | Indonesia University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07366398 Comparator | Feb → May 2025 | chronic gingivitis | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT06325566 Background | Jul 2024 → Jul 2027 expected | intervertebral disk degenerative disorder | Mesoblast, Inc. | Active not recruiting | No outcome recorded |
| Phase 3 | NCT05746676 Comparator | Jan → Aug 2023 | periodontal disorder | October University for Modern Sciences and Arts | Unknown | No outcome recorded |
| Phase 3 | NCT05086939 Comparator | May 2021 → May 2025 overdue | osteoarthritis, knee | Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León | Active not recruiting | No outcome recorded |
| Phase 3 | NCT06034626 Background | Nov 2020 → Aug 2021 | eye adnexa disorder | Second Affiliated Hospital, School of Medicine, Zhejiang University | Completed | No outcome recorded |
| Phase 3 | NCT04426721 Comparator | Jun 2020 → Dec 2021 | osteoarthritis, knee | Humanitas Clinical and Research Center | Unknown | No outcome recorded |
| Phase 3 | NCT04980105 Comparator | Mar 2020 → Sep 2021 | osteoarthritis, knee | University of Wasit | Unknown | No outcome recorded |
| Phase 3 | NCT03477630 Comparator | Feb 2019 → Jul 2020 | osteoarthritis | Karla Andrea Arias Varela | Completed | No outcome recorded |
| Phase 3 | NCT02257957 Comparator | Nov 2014 → Sep 2015 | Sjogren syndrome, dry eye syndrome | National University of Colombia | Completed | No outcome recorded |
| Phase 3 | NCT02211521 Comparator | Aug 2014 → Oct 2015 | osteoarthritis, knee | Samsung Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT02448407 Comparator | Jan → Jun 2014 | osteoarthritis, knee | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud | Completed | No outcome recorded |
| Phase 3 | NCT02714543 Comparator | Nov 2013 → Aug 2015 | oral submucous fibrosis | The Oxford Dental College, Hospital and Research Center, Bangalore, India | Completed | No outcome recorded |
| Phase 3 | NCT02039531 Comparator | Aug 2011 → Feb 2013 | osteoarthritis, knee | Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias | Completed | No outcome recorded |
| Phase 426 trials | ||||||
| Phase 4 | NCT06587880 Comparator | Aug 2025 → Dec 2026 expected | alveolar periostitis | University of Jordan | Recruiting | No outcome recorded |
| Phase 4 | NCT06872151 Comparator | Mar 2025 | anus disorder, hemorrhoid | University of Cagliari | Completed | No outcome recorded |
| Phase 4 | NCT06822608 Comparator | Feb → Nov 2025 overdue | corneal disorder | National and Kapodistrian University of Athens | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06508125 Comparator | Jul → Dec 2024 overdue | subacute bursitis | Taipei Medical University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06314256 Comparator | Apr 2024 → Jun 2025 | gingival recession | Altinbas University | Completed | No outcome recorded |
| Phase 4 | NCT06637384 Comparator | Mar → Apr 2024 | diabetes mellitus | Rimsha Rasheed | Completed | No outcome recorded |
| Phase 4 | NCT06426199 Comparator | Jan → Jun 2024 | temporomandibular joint disorder | Ain Shams University | Unknown | No outcome recorded |
| Phase 4 | NCT05492851 Comparator | Aug 2022 → Jan 2023 | osteoarthritis, knee | Ohio State University | Terminated | No outcome recorded |
| Phase 4 | NCT04373603 Background | Jul 2022 → Jul 2023 | — | University of Wisconsin, Madison | Withdrawn | No outcome recorded |
| Phase 4 | NCT05291650 Comparator | Apr 2022 → Sep 2023 | osteoarthritis, knee | Zhujiang Hospital | Completed | No outcome recorded |
| Phase 4 | NCT05562518 Comparator | Mar 2022 → Mar 2026 overdue | breast cancer, postmenopausal atrophic vaginitis | University Hospital, Ghent | Active not recruiting | No outcome recorded |
| Phase 4 | NCT06176937 Comparator | Oct 2021 → Feb 2022 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 4 | NCT04671914 Comparator | Sep 2021 → Mar 2025 | Asherman syndrome | Institute for the Care of Mother and Child, Prague, Czech Republic | Unknown | No outcome recorded |
| Phase 4 | NCT04521387 Comparator | Feb 2021 → May 2022 | epicondylitis | Wroclaw Medical University | Unknown | No outcome recorded |
| Phase 4 | NCT04095572 Comparator | Oct 2020 → Jun 2025 overdue | urinary tract infection | University Hospital, Basel, Switzerland | Recruiting | No outcome recorded |
| Phase 4 | NCT05220527 Background | Aug 2020 → Jul 2022 | osteoarthritis, knee | Taipei Medical University | Unknown | No outcome recorded |
| Phase 4 | NCT04117893 Background | Oct 2019 → Jun 2021 | chronic pain syndrome, osteoarthritis, knee | Beijing Tiantan Hospital | Completed | No outcome recorded |
| Phase 4 | NCT03888183 Comparator | Apr 2019 → Jan 2020 | dry eye syndrome | Chang Gung Memorial Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT04390100 Comparator | Feb → Dec 2019 | — | Ain Shams University | Completed | No outcome recorded |
| Phase 4 | NCT04188561 Comparator | Apr 2018 → Jan 2019 | osteoarthritis, knee | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT03245463 Comparator | Aug 2017 → Feb 2018 | osteoarthritis, knee | Hospital for Special Surgery, New York | Completed | No outcome recorded |
| Phase 4 | NCT02984228 Comparator | Dec 2014 → Nov 2020 | osteoarthritis | Hospital for Special Surgery, New York | Completed | No outcome recorded |
| Phase 4 | NCT03188289 Comparator | Jan → Jul 2014 | impacted teeth, multiple | University of Santiago de Compostela | Completed | No outcome recorded |
| Phase 4 | NCT04110587 Comparator | Dec 2013 → Jul 2019 | temporomandibular joint dysfunction syndrome | Universidad Complutense de Madrid | Completed | No outcome recorded |
| Phase 4 | NCT01948583 Comparator | May 2013 | vaginal disorder | Derming SRL | Completed | No outcome recorded |
| Phase 4 | NCT01290497 Comparator | Nov 2010 → Oct 2011 | osteoarthritis, knee | Tedec-Meiji Farma, S.A. | Completed | No outcome recorded |
| Phase not applicable26 trials | ||||||
| — | NCT07646483 Comparator | Jun 2026 → Sep 2027 expected | osteoarthritis, knee | PharmaResearch | Not yet recruiting | No outcome recorded |
| — | NCT07121556 Comparator | Sep 2025 → Sep 2030 expected | osteoarthritis, knee | Rizzoli Orthopaedic Institute | Recruiting | No outcome recorded |
| — | NCT07292870 Comparator | Aug 2025 → Dec 2027 expected | periodontitis, aggressive | Universitaire Ziekenhuizen KU Leuven | Recruiting | No outcome recorded |
| — | NCT06521333 Comparator | May 2024 → Dec 2025 | gingival recession | Cairo University | Completed | No outcome recorded |
| — | NCT06653985 Background | May 2024 → Oct 2026 expected | osteoarthritis | ArthroBiologix Inc. | Recruiting | No outcome recorded |
| — | NCT06078449 Background | Nov 2023 → Mar 2024 | osteoarthritis, knee | Badr University | Unknown | No outcome recorded |
| — | NCT05571527 Comparator | Nov 2023 → Mar 2024 | — | Kanuni Sultan Suleyman Training and Research Hospital | Unknown | No outcome recorded |
| — | NCT06576245 Background | Sep 2023 → Feb 2024 | dry eye syndrome | University of Seville | Completed | No outcome recorded |
| — | NCT05887336 Comparator | Jun 2023 → Aug 2024 | dry eye syndrome | Abilion Medical Systems AB | Completed | No outcome recorded |
| — | NCT05783479 Comparator | Jun → Dec 2022 | uterine polyp | Jagiellonian University | Completed | No outcome recorded |
| — | NCT05161403 Comparator | Feb 2022 → Sep 2023 | — | Cairo University | Unknown | No outcome recorded |
| — | NCT06332365 Comparator | Jan 2022 → Dec 2023 | lichen planus, oral | Pia Lopez Jornet | Completed | No outcome recorded |
| — | NCT04816253 Comparator | Feb → Jun 2021 | — | Al-Azhar University | Completed | No outcome recorded |
| — | NCT03167333 Comparator | Mar 2020 | osteoarthritis, knee, synovitis | Taipei Veterans General Hospital, Taiwan | Unknown | No outcome recorded |
| — | NCT04673916 Comparator | Jun 2019 → Feb 2020 | lichen planus, oral, preneoplastic lesion | University of Messina | Completed | No outcome recorded |
| — | NCT03814707 Comparator | Jan → Jun 2019 | — | mostafa soliman | Unknown | No outcome recorded |
| — | NCT03761472 Comparator | Jan 2019 → Jan 2020 | osteoarthritis, knee | Bezmialem Vakif University | Completed | No outcome recorded |
| — | NCT03690232 Comparator | Oct 2018 → Jun 2020 | osteoarthritis, knee | Taipei Veterans General Hospital, Taiwan | Unknown | No outcome recorded |
| — | NCT03242707 Comparator | Jul 2018 → Dec 2019 | osteoarthritis, knee | University of Southern California | Unknown | No outcome recorded |
| — | NCT03290365 Comparator | Jan 2018 → Jul 2021 | osteoarthritis, knee | Tri-Service General Hospital (TSGH) | Completed | No outcome recorded |
| — | NCT03357575 Comparator | Jan 2018 → Jun 2020 | osteoarthritis, knee | Peking University People's Hospital | Unknown | No outcome recorded |
| — | NCT02601170 Comparator | Jun 2014 → May 2016 | hemophilia, hemophilic arthropathy | Tri-Service General Hospital (TSGH) | Completed | No outcome recorded |
| — | NCT02136901 Comparator | Jun 2014 → Jun 2020 | osteoarthritis | Active Implants | Completed | No outcome recorded |
| — | NCT04833738 Comparator | Sep → Dec 2013 | shoulder impingement syndrome | Şeyhmus KAPLAN | Completed | No outcome recorded |
| — | NCT02588872 Comparator | Aug 2011 → Apr 2015 | osteoarthritis, knee | Rush University Medical Center | Completed | No outcome recorded |
| — | NCT01469507 Comparator | — | osteoarthritis, knee | Pierre Fabre Laboratories | Withdrawn | No outcome recorded |
Press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2019-07-01 | Teva Branded Pharmaceutical Products R&D, Inc. | Teva Announces Launch of 1% Sodium Hyaluronate in the United States tevapharm.com ↗ |
Evidence & citations 67 cited values
Every value below carries the sentence it was read from. 281 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | HYALURONIC ACID | “30 drops of topical antioxidants (Gluconolactone 4%, Hyaluronic acid 0,01%, Allantoin 0,1%, Ferulic acid 3%, Acetyl heptapeptide 0,001%, Silver vine extract 1%, Ectoine 0,01%,...” NCT06170346 ↗250“Subjects who had received an injection of Cingal in the 13-01 study will receive a single 4 milliliter (mL) intra-articular injection of Cingal (88 milligrams Hyaluronic Acid...” NCT02381652 ↗ “The ERIPTO study seeks to study a proposed protocol utilizing various components of regenerative medicine including platelet rich plasma (PRP), hyaluronic acid (HA), and human...” NCT04222140 ↗ “Hyaluronic acid is currently used in periodontal regenerative surgery as a hydrogel mixture of cross-linked (1.6%) and natural (0.2%) HA of bacterial origin, marketed as...” NCT07581613 ↗ “combination cream consist of Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic acid will be given to subjects to be applied every...” NCT06775314 ↗ “Patients included in the study had been received 2 ml high molecular weight (1.476 x 106 average Daltons) hyaluronic acid with concentration of 22mg/ml (OPTIVISC UK hyaluronic...” NCT04188561 ↗ “Intra-Articular Injection is an injection of 3-6 milliliter (mL) hyaluronic acid (HA) mixed with 1 milliliter (mL) depo methylprednisolone (a steroid) and 2 mL 0.5% bupivacaine...” NCT04504812 ↗ “Participants will receive rexlemestrocel-L 2.0 mL injection of approximately 6 million rexlemestrocel-L cells in freeze media mixed in a 1:1 by-volume ratio with hyaluronic...” NCT06325566 ↗ “Cingal is a combination product consisting of 88 milligrams of cross-linked HA (hyaluronic acid) with 18 milligrams of TH (triamcinolone hexacetonide) in a 4 milliliter (mL)...” NCT03191903 ↗ “INTRODUCTION: To compare the efficacy and safety of a low-viscosity 0.3% hyaluronic acid (HA) ophthalmic solution with those of a comparator 0.3% HA formulation in patients...” PMID 41995979 ↗ Apr 2026 “A high molecular weight polysaccharide, hyaluronic acid, also known as hyaluronan or hyaluronate, has recently been studied as a promising mediator for periodontal regeneration.” NCT04274244 ↗ “The study tests the efficacy of hyaluronic acid (HYL) mouthwash as adjunct to Chlorhexidine (CHX) mouthwash compared to Chlorhexidine mouthwash only in 16 gingivitis patients.” NCT07366398 ↗ “ANALGESIC EFFECT of ULTRASOUND GUIDED INTRA- ARTICULAR INJECTION of PLATELET RICH FIBRIN VERSUS INJECTION of HYALURONIC ACID in PATIENTS with MODERATE KNEE OSTEOARTHRITIS.” NCT06797960 ↗ “Our objective is to evaluate what is the best dosage of viscosupplementation with hyaluronic acid (OSTEONIL®) associated with 1 ml (20 mg) of triamcinolone hexacetonide.” NCT01824485 ↗ “0.05% cyclosporine A (Cyporin N Eye Drops, Taejoon Pharm, Republic of Korea) and 0.15% hyaluronic acid (New Hyaluni Eye Drops, Taejoon Pharm) were used in this study.” NCT06936462 ↗ “Patients will receive an ultrasound-guided injection consisting of 3 ml hyaluronic acid (Durolane™) mixed with 40 mg triamcinolone (Kenalog™) into their hip joint.” NCT06653985 ↗ “treated with an injection of high-molecular-weight hyaluronic acid (4 cc) and microfragmented autologous adipose tissue (6 cc), harvested from the abdominal site” NCT07121556 ↗ “Women were randomly assigned in a 1:1 ratio to surgery alone (control group) or surgery with intrauterine instillation of hyaluronic acid gel (gel group).” PMID 35667420 ↗ Jun 2022 “the second group will receive 1 mm hyaluronic acid injection and the third group will receive a mixture of 1 ml hyaluronic acid, 1 ml of injectable PRF” NCT06446843 ↗ “This trial is a randomized, parallel-group, double-blind, controlled clinical trial to evaluate the effect of hyaluronic acid (HA) on dry eye disease.” NCT03888183 ↗ “Transdermal injection of the filler agent composed of mesenchymal stem cells derived from autologous adipose tissue associated with hyaluronic acid.” NCT02034786 ↗ “Single dose of hyaluronic acid (HA) will be administrated intraarticularly as an active control in patients enrolled in "Control Patients" groups.” NCT05081921 ↗ “The most prescribed artificial tear remedies contain hyaluronic acid (HA), which enhances epithelial wound healing, improving tissue health.” PMID 29189737 ↗ Nov 2017 “Hyaluronic Acid Vaginal Insert (Revaree). A 2g vaginal insert that contains 5mg of HLA sodium salt and a base of semi-synthetic glycerides.” NCT04544475 ↗ “Injectables, including IncobutolinumtoxinA, hyaluronic acid (HA), and calcium hydroxyapatite, have grown in popularity over the past decade” NCT05039723 ↗ “A single 3 ml hyaluronic acid (HA) injection (viscosupplementation) performed the day after ACL reconstruction, after drainage removal” NCT02630407 ↗ “50 participants will receive the investigational drug (Chondrogen and Hyaluronic Acid) through the intra-articular injection method.” NCT04520945 ↗ “Participants will receive hyaluronic acid filler injections (Juvéderm Volux XC) for contouring of the jawline.” NCT06694857 ↗ “infiltration of the hip joint with hyaluronic acid, with a corticosteroid or with 0.125% bupivacaine.” PMID 21080920 ↗ Nov 2010 “lavage with saline solution followed by injection of 10mg of hyaluronic acid with mannitol (5mg).” NCT03089723 ↗ “It contains calcium hydroxide, hyaluronic acid, Umbelliferone and Oligomeric Proanthocyanidins.” NCT04673916 ↗ “Epigallocatechin gallate 200mg, Hyaluronic acid 50mg, Vitamin B12 1mg, Folic acid 400mcg” NCT06098456 ↗ “application of hormone-free vaginal-vulvar moisturizing cream containing hyaluronic acid” NCT06031493 ↗ “Composition: Cross-linked hyaluronic acid (HA): 25 mg/ml Lidocaine; 0,3%, (injection).” NCT06314256 ↗ “the control group, a sodium hyaluronate (hyaluronic acid/hyaluronan) vehicle control.” PMID 24430407 ↗ Jan 2014 “Brightening Day Cream - SPF 15 (5% Azelaic Acid, 2% Hyaluronic Acid, 1%Niacinamide)” NCT05446402 ↗ “Hyaluronic Acid (HA) dressing as compared to Hyaluronic Acid alone.” NCT06680856 ↗ “Idroflog® (0.2% Hyaluronic Acid with 0.001% Hydrocortisone)” NCT06576245 ↗ “Hyaluronic acid and corticosteroids mixture injection” NCT07598253 ↗ “Revaree Plus is a hyaluronic acid vaginal suppository” NCT07042581 ↗ “Hyaluronic Acid with Triamcinolone Hexacetonide” NCT03390036 ↗ “followed by an IA injection of hyaluronic acid.” NCT04893174 ↗ “locally administered hyaluronic acid” NCT05562518 ↗ “Device: Hyaluronic Acid Injection” NCT01442571 ↗ “0.15% hyaluronic acid substitute” NCT06517667 ↗ “Hyaluronic acid (HyloGel)” NCT05887336 ↗ “hyaluronic acid group” NCT03690232 ↗ “Hyaluronic Acid 20 mg” NCT04453111 ↗ “Hyaluronic acid (HA)” NCT04095572 ↗ “Hyaluronic Acid (HA)” NCT07510295 ↗ “Hyaluronic acid (HA)” NCT02832713 ↗ “Hyaluronic Acid (HA)” NCT03491761 ↗ “Hyaluronic acid” NCT06238934 ↗ |
| Known as | ACP gel | “intrauterine application of auto-crosslinked hyaluronic acid (ACP) gel, after dilatation and curettage (D&C), reduces the incidence of intrauterine adhesions (IUAs)” PMID 28390688 ↗ Apr 2017 |
| Known as | Artibest | “Patients in the experimental group received ultrasound-guided intra-articular injections of hyaluronic acid (Artibest, 60 mg/3 ml, 2%, manufactured by Kang Stem Biotech,...” NCT05983081 ↗ |
| Known as | ARTZDispo | “five weekly intra-articular injections of 2.5 mL of hyaluronate sodium (ARTZDispo, Seikagaku Corporation Japan).” NCT02601170 ↗ |
| Known as | Belotero | “combination, global facial and/or neck treatment with IncobotulinumA (Xeomin), HA (Belotero) and/or calcium hydroxyapatite (Radiesse+, Radiesse Classic).” NCT05039723 ↗ |
| Known as | Blad-Care | “Hyaluronic Acid and Chondroitin Sulfate (Blad-Care™)” NCT07495072 ↗ |
| Known as | CTX-100 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00993707 ↗ |
| Known as | Durolane | “one intraarticular injection of hyaluronan (HA) 3 ml (Durolane®, 20 mg/ml non-animal stabilized hyaluronic acid (NASHA) in buffered physiological sodium chloride solution pH 7...” NCT00731289 ↗2“Patients will receive an ultrasound-guided injection consisting of 3 ml hyaluronic acid (Durolane™) mixed with 40 mg triamcinolone (Kenalog™) into their hip joint.” NCT06653985 ↗ “Hyaluronic acid (Durolane)” NCT01586312 ↗ |
| Known as | EmbryoGlue | “Hyaluronic Acid(EmbryoGlue®)” NCT06492785 ↗ |
| Known as | EUFLEXXA | “with and without EUFLEXXA, for the treatment of Knee Osteoarthritis” NCT06463132 ↗ |
| Known as | G2 medium | “Hyaluronic Acid (G2 medium)” NCT06492785 ↗ |
| Known as | Gel-One | “an injection of Gel-One® (hyaluronan, 3 mL) 1-2 weeks after ACL surgery” NCT03429140 ↗ |
| Known as | Gengiegel | “hyaluronic acid (Gengiegel 0.2% oral gel )” NCT04390100 ↗ |
| Known as | Gengigel | “The aim of the present study was to evaluate the clinical and microbial efficacy of local delivery of minocycline gel 2% and 0.2% hyaluronan gel (Gengigel) as an adjunctive...” NCT06997731 ↗3“Commercially available hyaluronic acid mouthrinse (Gengigel®, Ricerfarma, Milan, Italy).” NCT07689695 ↗ |
| Known as | Gengigel Oral Forte Gel | “0.8% hyaluronic acid gel (Gengigel Oral Forte Gel, Ricefarma, Milan, Italy)” NCT07437885 ↗ |
| Known as | Gengigel Prof | “0.8% polyvinylpyrrolidone sodium hyaluronate (HA) (Gengigel Prof, Ricerfarma SRL.) gel was impregnated on a sterile gelatin sponge” NCT06867055 ↗ |
| Known as | HA | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02412735 ↗ |
| Known as | HA gel | “For the Hyaluronic acid gel group: HA gel was injected 2-3mm apical to the coronal tip of the involved papillae” NCT05953896 ↗ |
| Known as | HANBIO BarriGel | “patients undergoing thyroidectomy were randomized 1 : 1 : 1 to receive oxidized regenerated cellulose (Interceed™), high molecular weight hyaluronic acid (HANBIO BarriGel), or...” PMID 40613790 ↗ Jul 2025 |
| Known as | Healon 5 - hyaluronic acid 23mg/ml | “Healon 5 - hyaluronic acid 23mg/ml” NCT00607685 ↗ |
| Known as | Hialid | “0.3% hyaluronic acid eye drops (Hialid; Santen, Osaka, Japan) four times a day during the study, including the follow-up period.” NCT06034626 ↗ |
| Known as | high-molecular-weight Hyaluronic Acid | “High-molecular-weight hyaluronic acid (HMWHA) plays a crucial role in immune tolerance at the maternal-fetal interface, promotes anti-inflammatory cytokine secretion, and...” NCT07305519 ↗ |
| Known as | HMWHA | “High-molecular-weight hyaluronic acid (HMWHA) plays a crucial role in immune tolerance at the maternal-fetal interface, promotes anti-inflammatory cytokine secretion, and...” NCT07305519 ↗ |
| Known as | hyaDENT BG | “Hyaluronic acid is currently used in periodontal regenerative surgery as a hydrogel mixture of cross-linked (1.6%) and natural (0.2%) HA of bacterial origin, marketed as...” NCT07581613 ↗1“Hyaluronic Acid (HYADENT BG)” NCT04821804 ↗ |
| Known as | Hyajoint | “a single HA injection (Hyajoint) weekly for 3 weeks” NCT04443166 ↗ |
| Known as | HYAJOINT Plus | “In the HA group, HYAJOINT Plus containing 60 mg of purified sodium hyaluronate was used in a single-dose treatment.” NCT04972383 ↗1“a single crosslinked hyaluronan (HYAJOINT Plus) and a single PRP versus a single PRP in patients with knee OA” PMID 33420185 ↗ Jan 2021 |
| Known as | Hyal One | “Single intraarticular injection of Hyaluronic acid (Hyal One)” NCT02123368 ↗ |
| Known as | Hyalgan | “intraarticular hyaluronic acid (20 mg/2 mL; Hyalgan, Fidia, Abano Terme, Italy) injections at the same intervals” NCT02958761 ↗ |
| Known as | hyaluronan | “Generic Name: Hyaluronan The Monovisc™ device is a proprietary high molecular weight hyaluronic acid (HA) viscosupplementation intended for the treatment of pain in patients...” NCT05492851 ↗16“one intraarticular injection of hyaluronan (HA) 3 ml (Durolane®, 20 mg/ml non-animal stabilized hyaluronic acid (NASHA) in buffered physiological sodium chloride solution pH 7...” NCT00731289 ↗ “A high molecular weight polysaccharide, hyaluronic acid, also known as hyaluronan or hyaluronate, has recently been studied as a promising mediator for periodontal regeneration.” NCT04274244 ↗ “a single crosslinked hyaluronan (HYAJOINT Plus) and a single PRP versus a single PRP in patients with knee OA” PMID 33420185 ↗ Jan 2021 “Hyaluronic acid (hyaluronan) is a glycosaminoglycan with anti-inflammatory and antiedematous properties.” PMID 12622859 ↗ Feb 2003 “Single intraarticular dose of allogeneic MSCs suspended in 2ml Plasmalyte followed by 2ml of Hyaluronan” NCT01448434 ↗ “an injection of Gel-One® (hyaluronan, 3 mL) 1-2 weeks after ACL surgery” NCT03429140 ↗ “Single intraarticular dose of 2ml Plasmalyte followed by 2ml Hyaluronan” NCT01453738 ↗ |
| Known as | Hyaluronan acid : Neovisc | “Hyaluronan acid : Neovisc®” NCT02086474 ↗ |
| Known as | hyaluronate | “A high molecular weight polysaccharide, hyaluronic acid, also known as hyaluronan or hyaluronate, has recently been studied as a promising mediator for periodontal regeneration.” NCT04274244 ↗ |
| Known as | Hyaluronic acid (Artz, Seikagaku, Japan) | “Hyaluronic acid (Artz®, Seikagaku, Japan)” NCT01950793 ↗ |
| Known as | Hyaluronic Acid and Chondroitin Sulfate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT07495072 ↗ |
| Known as | hyaluronic acid and chondroitin sulphate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02366676 ↗ |
| Known as | Hyaluronic acid and Trehalos | “Hyaluronic acid and Trehalos (Theloz Duo)” NCT05887336 ↗ |
| Known as | hyaluronic acid sodium salt | “hyaluronic acid sodium salt, Synvisc-One (TRB Chemedica Ltd.)” NCT04326985 ↗ |
| Known as | Hyaluronic acid/chondroitin sulfate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01813565 ↗ |
| Known as | HYL | “The study tests the efficacy of hyaluronic acid (HYL) mouthwash as adjunct to Chlorhexidine (CHX) mouthwash compared to Chlorhexidine mouthwash only in 16 gingivitis patients.” NCT07366398 ↗ |
| Known as | Hylan G-F 20 | “Intraarticular injection of 2 ml hyaluronic acid (Synvisc-One® Hylan G-F 20, Sanofi-Aventis)” NCT03800810 ↗ |
| Known as | HYLO COMOD eye drops | “Participants in both groups received hyaluronic acid eye drops (HYLO COMOD® eye drops, Ursapharm, Ltd., Germany) with the treatment of 3 times a day.” NCT04673643 ↗1“Participants in both groups received hyaluronic acid eye drops (HYLO COMOD® eye drops, Ursapharm, Ltd., Germany) with the treatment of 3 times a day.” NCT06544447 ↗ |
| Known as | HyloGel | “Hyaluronic acid (HyloGel)” NCT05887336 ↗ |
| Known as | Hymovis | “the first one received a single injection of HA (Hymovis 24 mg/3ml, Fidia Farmaceutici Spa, Padova, Italy) at the end of the arthroscopic meniscectomy” NCT02629380 ↗ |
| Known as | hyruan | “hyaluronic acid (hyruan)” NCT02708706 ↗ |
| Known as | Hyruan Plus | “The HA group was administered intra-articular HA ((Hyruan Plus® , average MW 3000 kD; LG Life Sciences Ltd, Korea)) for sessions with a 1-week interval between each treatment” NCT03690232 ↗ |
| Known as | Hyruan Plus Inj (Sodium Hyaluronate 10.0mg) [LG Chem] | “Hyruan Plus Inj (Sodium Hyaluronate 10.0mg) [LG Chem]” NCT06437054 ↗ |
| Known as | Juvéderm Volux XC | “Participants will receive hyaluronic acid filler injections (Juvéderm Volux XC) for contouring of the jawline.” NCT06694857 ↗ |
| Known as | Monovisc | “Generic Name: Hyaluronan The Monovisc™ device is a proprietary high molecular weight hyaluronic acid (HA) viscosupplementation intended for the treatment of pain in patients...” NCT05492851 ↗ |
| Known as | New Hyaluni Eye Drops | “0.05% cyclosporine A (Cyporin N Eye Drops, Taejoon Pharm, Republic of Korea) and 0.15% hyaluronic acid (New Hyaluni Eye Drops, Taejoon Pharm) were used in this study.” NCT06936462 ↗ |
| Known as | OPTIVISC UK | “Patients included in the study had been received 2 ml high molecular weight (1.476 x 106 average Daltons) hyaluronic acid with concentration of 22mg/ml (OPTIVISC UK hyaluronic...” NCT04188561 ↗ |
| Known as | Orthovisc | “Intra-articular injection of hyaluronic acid (Orthovisc) into the temporomandibular joint following arthrocentesis.” NCT07479693 ↗1“Orthovisc injection” NCT00436969 ↗ |
| Known as | OSTEONIL | “Our objective is to evaluate what is the best dosage of viscosupplementation with hyaluronic acid (OSTEONIL®) associated with 1 ml (20 mg) of triamcinolone hexacetonide.” NCT01824485 ↗ |
| Known as | polyvinylpyrrolidone sodium hyaluronate | “0.8% polyvinylpyrrolidone sodium hyaluronate (HA) (Gengigel Prof, Ricerfarma SRL.) gel was impregnated on a sterile gelatin sponge” NCT06867055 ↗ |
| Known as | Q-Afta | “Participants in the experimental group will use a hyaluronic acid mouthwash (Q-Afta®, CIRA Pharma, Egypt).” NCT07662226 ↗ |
| Known as | REGENFAST | “The clinician will use hyaluronic acid (REGENFAST®) as adjuvant in the surgical treatment of the intra-bony defects in conjunction with minimally invasive surgery” NCT07292870 ↗ |
| Known as | Revaree | “Hyaluronic Acid Vaginal Insert (Revaree). A 2g vaginal insert that contains 5mg of HLA sodium salt and a base of semi-synthetic glycerides.” NCT04544475 ↗ |
| Known as | Revaree Plus | “Revaree Plus is a hyaluronic acid vaginal suppository” NCT07042581 ↗ |
| Known as | Sinovial | “Patients will receive intralesional treatment with Hyaluronic acid (0.8% highly purified sodium salt Hyaluronic acid16 mg/2 mL; Sinovial, IBSA, Lodi, Italy) weekly for 12 weeks.” NCT05855070 ↗ |
| Known as | sodium hyaluronate | “the control group, a sodium hyaluronate (hyaluronic acid/hyaluronan) vehicle control.” PMID 24430407 ↗ Jan 2014 |
| Known as | Synolis VA | “Synolis VA is a viscoelastic, sterile, non-pyrogenic, isotonic, buffered solution of 2% hyaluronic acid.” NCT05450458 ↗1“Hyaluronic acid (Synolis VA)” NCT05076526 ↗ |
| Known as | SYNVISC HA Injections | “Intra-articular injection of a hyaluronic acid treatment, such as SYNVISC® HA Injections.” NCT02136901 ↗ |
| Known as | Synvisc-One | “Intraarticular injection of 2 ml hyaluronic acid (Synvisc-One® Hylan G-F 20, Sanofi-Aventis)” NCT03800810 ↗2“Hyaluronic Acid - Synvisc-One®: A high molecular weight sodium hyaluronate (HA).” NCT03242707 ↗ “hyaluronic acid sodium salt, Synvisc-One (TRB Chemedica Ltd.)” NCT04326985 ↗ |
| Known as | Teosyal PureSense Global Action | “hyaluronic acid (HA; Teosyal® PureSense Global Action, Teoxane Laboratories, Geneva, Switzerland).” NCT03459833 ↗ |
| Known as | Theloz Duo | “Hyaluronic acid and Trehalos (Theloz Duo)” NCT05887336 ↗ |
| Action | Activate | “supports progesterone-mediated uterine quiescence through upregulation of the progesterone receptor membrane component-1 (PGRMC1)” NCT07305519 ↗ |
| Modality | Other / unclassified | “Hyaluronic acid (HA) is a biomaterial” NCT03871218 ↗ |
| Route | Other | “injection into the shoulder” NCT00436969 ↗ |
| Target | PGRMC1 | “through upregulation of the progesterone receptor membrane component-1 (PGRMC1)” NCT07305519 ↗ |